DE3070896D1 - Monoclonal antibody to human helper t cells, method of preparing it, hybrid cell line producing it, its diagnostic and therapeutic uses and diagnostic and therapeutic compositions comprising it - Google Patents
Monoclonal antibody to human helper t cells, method of preparing it, hybrid cell line producing it, its diagnostic and therapeutic uses and diagnostic and therapeutic compositions comprising itInfo
- Publication number
- DE3070896D1 DE3070896D1 DE8080301356T DE3070896T DE3070896D1 DE 3070896 D1 DE3070896 D1 DE 3070896D1 DE 8080301356 T DE8080301356 T DE 8080301356T DE 3070896 T DE3070896 T DE 3070896T DE 3070896 D1 DE3070896 D1 DE 3070896D1
- Authority
- DE
- Germany
- Prior art keywords
- diagnostic
- monoclonal antibody
- cells
- cell line
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3061—Blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/966—Chemistry: molecular biology and microbiology involving an enzyme system with high turnover rate or complement magnified assay, e.g. multi-enzyme systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/033,639 US4381295A (en) | 1979-04-26 | 1979-04-26 | Monoclonal antibody to human helper T cells and methods of preparing same |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3070896D1 true DE3070896D1 (en) | 1985-08-29 |
Family
ID=21871570
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE198080301356T Pending DE18794T1 (de) | 1979-04-26 | 1980-04-25 | Monoklonaler antikoerper gegen menschliche helfer-t-zellen, verfahren zu seiner herstellung, ihn produzierende hybridzellinie, seine diagnostischen und therapeutischen verwendungen und diesen antikoerper enthaltende diagnostische und therapeutische zusammensetzungen. |
DE8080301356T Expired DE3070896D1 (en) | 1979-04-26 | 1980-04-25 | Monoclonal antibody to human helper t cells, method of preparing it, hybrid cell line producing it, its diagnostic and therapeutic uses and diagnostic and therapeutic compositions comprising it |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE198080301356T Pending DE18794T1 (de) | 1979-04-26 | 1980-04-25 | Monoklonaler antikoerper gegen menschliche helfer-t-zellen, verfahren zu seiner herstellung, ihn produzierende hybridzellinie, seine diagnostischen und therapeutischen verwendungen und diesen antikoerper enthaltende diagnostische und therapeutische zusammensetzungen. |
Country Status (22)
Country | Link |
---|---|
US (1) | US4381295A (de) |
EP (1) | EP0018794B1 (de) |
JP (2) | JPS55145616A (de) |
AT (1) | ATE14454T1 (de) |
AU (1) | AU544792B2 (de) |
CA (1) | CA1170592A (de) |
DE (2) | DE18794T1 (de) |
DK (1) | DK154087C (de) |
ES (1) | ES8105151A1 (de) |
FI (1) | FI75363C (de) |
GR (1) | GR67298B (de) |
HK (1) | HK23786A (de) |
IE (1) | IE50459B1 (de) |
IL (1) | IL59919A (de) |
MY (1) | MY8600513A (de) |
NO (1) | NO159883C (de) |
NZ (1) | NZ193470A (de) |
PH (1) | PH16656A (de) |
PT (1) | PT71148B (de) |
SG (1) | SG6586G (de) |
YU (1) | YU44957B (de) |
ZA (1) | ZA802524B (de) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4381292A (en) * | 1980-11-14 | 1983-04-26 | The Board Of Trustees Of The Leland Stanford Jr. University | Anti-human T-lymphocyte monoclonal antibody |
US4824432A (en) * | 1981-03-24 | 1989-04-25 | S.V.S. Laboratories, Inc. | Method for treating AIDS and other immune deficiencies and immune disorders |
US4474893A (en) * | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
USRE32011E (en) * | 1981-12-14 | 1985-10-22 | Scripps Clinic And Research Foundation | Ultrapurification of factor VIII using monoclonal antibodies |
US4511662A (en) * | 1982-06-18 | 1985-04-16 | Bio-Rad Laboratories, Inc. | Simultaneous assay for T and B lymphocyte populations and subpopulations |
US4443427A (en) * | 1982-06-21 | 1984-04-17 | Sidney Farber Cancer Institute, Inc. | Monoclonal antibody |
US4582790A (en) * | 1983-02-15 | 1986-04-15 | Wisconsin Alumni Research Foundation | Monoclonal antibody to angiotension-converting enzyme and methods of preparing and using same |
US4550086A (en) * | 1983-02-16 | 1985-10-29 | Dana-Farber Cancer Institute, Inc. | Monoclonal antibodies that recognize human T cells |
US4677056A (en) * | 1983-08-18 | 1987-06-30 | Sloan-Kettering Institute For Cancer Research | Monoclonal antibody subsetting human helper and killer T-cells and method |
IL69686A (en) * | 1983-09-11 | 1988-03-31 | Yeda Res & Dev | Compositions containing cell membrane proteins and process for their preparation |
USRE35277E (en) * | 1983-09-11 | 1996-06-18 | Yeda Research And Development Co. Ltd. | Cell membrane proteins, compositions containing them and procedure for their preparation |
US4645738A (en) * | 1983-09-30 | 1987-02-24 | Memorial Sloan-Kettering Institute Cancer Center | Method for differential diagnosis of T cell leukemias using monoclonal antibodies |
JPS60231699A (ja) * | 1983-11-09 | 1985-11-18 | Aichiken | 正常及び悪性ヒト造血器細胞に対するモノクローナル抗体 |
US4469630A (en) * | 1983-11-25 | 1984-09-04 | J. T. Baker Chemical Co. | Purification of monoclonal antibodies |
EP0146050B1 (de) | 1983-12-16 | 1990-07-04 | Denis M. Callewaert | Stellenselektiver Plasminogenaktivator und Verfahren zu seiner Herstellung und Verwendung |
US5130144B1 (en) * | 1984-02-06 | 1995-08-15 | Univ Johns Hopkins | Human stem cells and monoclonal antibodies |
US4965204A (en) * | 1984-02-06 | 1990-10-23 | The Johns Hopkins University | Human stem cells and monoclonal antibodies |
US4604235A (en) * | 1984-05-23 | 1986-08-05 | J. T. Baker Chemical Company | Purification of monoclonal antibodies |
FR2570278B1 (fr) * | 1984-09-14 | 1987-02-13 | Pasteur Institut | Compositions et procede pour proteger les lymphocytes t contre l'agent etiologique des lymphadenopathies et du syndrome d'immunodepression acquise |
EP0335426B1 (de) * | 1984-09-14 | 1991-07-03 | Institut Pasteur | Zubereitungen und Verfahren zum Schutz von T-Lymphozyten gegen das Krankheitsagens von Lymphadenopathie und vom erworbenen Immundepressionsyndrom |
US4695459A (en) * | 1984-12-26 | 1987-09-22 | The Board Of Trustees Of Leland Stanford Junior University | Method of treating autoimmune diseases that are mediated by Leu3/CD4 phenotype T cells |
US4661446A (en) * | 1985-02-19 | 1987-04-28 | Dana-Farber Cancer Institute, Inc. | Monoclonal antibodies and method of immunizing therewith |
US5776093A (en) * | 1985-07-05 | 1998-07-07 | Immunomedics, Inc. | Method for imaging and treating organs and tissues |
DE3541033A1 (de) * | 1985-11-19 | 1987-05-21 | Boehringer Mannheim Gmbh | Verfahren zur quantifizierung von zellpopulationen bzw. subpopulationen sowie hierfuer geeignetes reagenz |
GB8608068D0 (en) * | 1986-04-02 | 1986-05-08 | Cobbold S P | Monoclonal antibodies |
CA1296622C (en) * | 1986-08-12 | 1992-03-03 | Jeffrey E. Anderson | Method and apparatus for automated assessment of the immunoregulatory status of the mononuclear leukocyte immune system |
US5601819A (en) * | 1988-08-11 | 1997-02-11 | The General Hospital Corporation | Bispecific antibodies for selective immune regulation and for selective immune cell binding |
US5068178A (en) * | 1988-12-06 | 1991-11-26 | Genetic Systems Corporation | Method of enhancing direct immunofluorescence staining of cells |
US7037496B2 (en) * | 1989-12-27 | 2006-05-02 | Centocor, Inc. | Chimeric immunoglobulin for CD4 receptors |
JPH0424999U (de) * | 1990-06-26 | 1992-02-28 | ||
GB9021677D0 (en) * | 1990-10-05 | 1990-11-21 | Xaar Ltd | Method of testing multi-channel array pulsed droplet deposition apparatus |
CA2073031C (en) * | 1990-11-27 | 2002-10-01 | Linda C. Burkly | Anti-cd4 antibody homologs useful in prophylaxis and treatment of aids, arc and hiv infection |
US5747265A (en) * | 1992-10-30 | 1998-05-05 | T Cell Diagnostics, Inc. | Method for measuring the amount of a cell-associated molecule |
ES2108460T3 (es) | 1993-06-03 | 1997-12-16 | Therapeutic Antibodies Inc | Fragmentos de anticuerpos en terapeutica. |
US5961976A (en) * | 1996-06-03 | 1999-10-05 | United Biomedical, Inc. | Antibodies against a host cell antigen complex for pre- and post-exposure protection from infection by HIV |
DK0963377T3 (da) | 1996-08-30 | 2009-05-18 | Human Genome Sciences Inc | Interleukin-19 |
EP1034003A4 (de) | 1997-11-24 | 2004-07-14 | Johnson T Wong | Methoden zur behandlung von hiv oder anderer infektionen unter verwendung eines t-zell-aktivators oder eines viralen aktivators und einer antiretroviralen kombinationstherapie |
US6790796B2 (en) | 2001-10-05 | 2004-09-14 | Albany International Corp. | Nonwovens forming or conveying fabrics with enhanced surface roughness and texture |
CA2645322A1 (en) * | 2006-03-16 | 2007-09-27 | Genentech, Inc. | Methods of treating lupus using cd4 antibodies |
US20080279848A1 (en) * | 2006-03-16 | 2008-11-13 | Genentech, Inc. | Methods of treating lupus using CD4 antibodies |
AR077718A1 (es) * | 2008-07-15 | 2011-09-21 | Genentech Inc | Metodos para tratar enfermedades autoinmunes usando anticuerpos anti cd4. formulacion farmaceutica |
WO2016043788A1 (en) | 2014-09-16 | 2016-03-24 | United Biomedical, Inc | Treatment and functional cure of hiv infection by monoclonal antibodies to cd4 mediating competitive hiv entry inhibition |
US11292839B2 (en) | 2016-08-13 | 2022-04-05 | Ubi Us Holdings, Llc | Treatment and sustained virologic remission of HIV infection by antibodies to CD4 in HAART stabilized patients |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4196265A (en) * | 1977-06-15 | 1980-04-01 | The Wistar Institute | Method of producing antibodies |
-
1979
- 1979-04-26 US US06/033,639 patent/US4381295A/en not_active Expired - Lifetime
-
1980
- 1980-04-01 CA CA000348981A patent/CA1170592A/en not_active Expired
- 1980-04-11 GR GR61667A patent/GR67298B/el unknown
- 1980-04-17 NZ NZ193470A patent/NZ193470A/en unknown
- 1980-04-24 AU AU57758/80A patent/AU544792B2/en not_active Expired
- 1980-04-24 IL IL59919A patent/IL59919A/xx unknown
- 1980-04-24 PT PT71148A patent/PT71148B/pt active IP Right Revival
- 1980-04-24 PH PH23948A patent/PH16656A/en unknown
- 1980-04-24 JP JP5369080A patent/JPS55145616A/ja active Granted
- 1980-04-25 DE DE198080301356T patent/DE18794T1/de active Pending
- 1980-04-25 NO NO801216A patent/NO159883C/no unknown
- 1980-04-25 DK DK180580A patent/DK154087C/da active
- 1980-04-25 DE DE8080301356T patent/DE3070896D1/de not_active Expired
- 1980-04-25 IE IE839/80A patent/IE50459B1/en not_active IP Right Cessation
- 1980-04-25 AT AT80301356T patent/ATE14454T1/de not_active IP Right Cessation
- 1980-04-25 ZA ZA00802524A patent/ZA802524B/xx unknown
- 1980-04-25 ES ES490943A patent/ES8105151A1/es not_active Expired
- 1980-04-25 YU YU1148/80A patent/YU44957B/xx unknown
- 1980-04-25 FI FI801343A patent/FI75363C/fi not_active IP Right Cessation
- 1980-04-25 EP EP80301356A patent/EP0018794B1/de not_active Expired
-
1986
- 1986-01-21 SG SG65/86A patent/SG6586G/en unknown
- 1986-04-03 HK HK237/86A patent/HK23786A/xx unknown
- 1986-12-30 MY MY513/86A patent/MY8600513A/xx unknown
-
1988
- 1988-04-26 JP JP63101497A patent/JPH0198477A/ja active Granted
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3070896D1 (en) | Monoclonal antibody to human helper t cells, method of preparing it, hybrid cell line producing it, its diagnostic and therapeutic uses and diagnostic and therapeutic compositions comprising it | |
AU545223B2 (en) | Hybrid cell line for producing monoclonal antibody | |
DE3070744D1 (en) | Hybrid cell line for producing complement-fixing, monoclonal antibody to human suppressor t cells, antibody, method of preparation of this antibody, diagnostic and therapeutic uses and pharmaceutical compositions comprising this antibody | |
DE3170352D1 (en) | Hybrid cell line for producing monoclonal antibody to a human t cell antigen, antibody, and methods | |
AU545181B2 (en) | Hybridoma for producing monoclonal antibodies | |
DE3070479D1 (en) | Hybrid cell line for producing monoclonal antibody to human thymocyte antigen, antibody, method of preparation of this antibody, diagnostic and therapeutic uses and pharmaceutical compositions comprising this antibody |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8328 | Change in the person/name/address of the agent |
Free format text: GRUENECKER, A., DIPL.-ING. KINKELDEY, H., DIPL.-ING. DR.-ING. STOCKMAIR, W., DIPL.-ING. DR.-ING. AE.E. CAL TECH SCHUMANN, K., DIPL.-PHYS. DR.RER.NAT. JAKOB, P., DIPL.-ING. BEZOLD, G., DIPL.-CHEM. DR.RER.NAT. MEISTER, W., DIPL.-ING. HILGERS, H., DIPL.-ING. MEYER-PLATH, H., DIPL.-ING. DR.-ING. KINKELDEY, U., DIPL.-BIOL. DR.RER.NAT. BOTT-BODENHAUSEN, M., DIPL.-PHYS. DR.RER.NAT., PAT.-ANW., 8000 MUENCHEN |
|
8363 | Opposition against the patent | ||
8331 | Complete revocation |