ZA78793B - 1,3-disubstituted(2-thio)ureas - Google Patents

1,3-disubstituted(2-thio)ureas

Info

Publication number
ZA78793B
ZA78793B ZA00780793A ZA78793A ZA78793B ZA 78793 B ZA78793 B ZA 78793B ZA 00780793 A ZA00780793 A ZA 00780793A ZA 78793 A ZA78793 A ZA 78793A ZA 78793 B ZA78793 B ZA 78793B
Authority
ZA
South Africa
Prior art keywords
ureas
disubstituted
thio
Prior art date
Application number
ZA00780793A
Other languages
English (en)
Inventor
J Lannoy
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of ZA78793B publication Critical patent/ZA78793B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C07D223/10—Oxygen atoms attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/02—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D227/00—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00
    • C07D227/02—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D227/06—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D227/08—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ZA00780793A 1977-02-10 1978-02-09 1,3-disubstituted(2-thio)ureas ZA78793B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5494/77A GB1582351A (en) 1977-02-10 1977-02-10 Disubstituted ureas and thioureas

Publications (1)

Publication Number Publication Date
ZA78793B true ZA78793B (en) 1979-01-31

Family

ID=9797264

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00780793A ZA78793B (en) 1977-02-10 1978-02-09 1,3-disubstituted(2-thio)ureas

Country Status (33)

Country Link
US (1) US4216221A (el)
JP (1) JPS53101366A (el)
AT (1) AT359080B (el)
AU (1) AU516765B2 (el)
BE (1) BE863792A (el)
BG (2) BG29646A2 (el)
CA (1) CA1078858A (el)
CH (1) CH632999A5 (el)
CS (1) CS207603B2 (el)
DD (1) DD134097A5 (el)
DE (1) DE2805769A1 (el)
DK (1) DK57778A (el)
ES (1) ES466815A1 (el)
FI (1) FI66601C (el)
FR (1) FR2380262A1 (el)
GB (1) GB1582351A (el)
GR (1) GR66187B (el)
HU (1) HU176033B (el)
IL (1) IL54011A (el)
IN (1) IN148262B (el)
IT (1) IT1102355B (el)
LU (1) LU79047A1 (el)
NL (1) NL7801572A (el)
NO (1) NO780431L (el)
NZ (1) NZ186425A (el)
OA (1) OA05883A (el)
PH (1) PH14362A (el)
PL (2) PL112570B1 (el)
PT (1) PT67637B (el)
SE (1) SE426593B (el)
SU (2) SU936810A3 (el)
YU (1) YU29778A (el)
ZA (1) ZA78793B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4792604A (en) * 1987-03-20 1988-12-20 Gaf Corporation Manufacture of haloalkyl lactams
US5334720A (en) * 1991-03-07 1994-08-02 Fisons Corporation Diphenyl-1-(aminoalkyl)-2-piperidinone and -2-pyrrolidinone derivatives having anticonvulsant properties
DE4127404A1 (de) * 1991-08-19 1993-02-25 Thomae Gmbh Dr K Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE19519498A1 (de) * 1995-05-27 1996-05-09 Hermann Trey Integriertes Diebstahl- und Transportsicherungssystem mit Alarmeinrichtung für mobile Gegenstände oder mobile Behältnisse
BRPI0417157A (pt) * 2003-12-02 2007-03-06 Ucb Sa composto, composição farmacêutica, e, uso de um composto ou de uma composição farmacêutica
FR2937973B1 (fr) * 2008-11-04 2010-11-05 Galderma Res & Dev Modulateurs des recepteurs de la melanocortine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
WO2015103756A1 (en) * 2014-01-09 2015-07-16 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2850529A (en) * 1955-03-28 1958-09-02 Pfizer & Co C Bis quaternary ammonia alkyl ureas
GB1039113A (en) * 1964-08-06 1966-08-17 Ucb Sa New n-substituted lactams
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines

Also Published As

Publication number Publication date
SE426593B (sv) 1983-01-31
PH14362A (en) 1981-06-03
AU3315578A (en) 1979-08-16
YU29778A (en) 1983-01-21
CH632999A5 (fr) 1982-11-15
FI66601B (fi) 1984-07-31
IN148262B (el) 1980-12-27
FR2380262A1 (fr) 1978-09-08
FI66601C (fi) 1984-11-12
FR2380262B1 (el) 1982-04-23
NZ186425A (en) 1980-04-28
GB1582351A (en) 1981-01-07
ES466815A1 (es) 1978-10-01
PL204532A1 (pl) 1978-12-04
LU79047A1 (fr) 1978-09-28
DE2805769C2 (el) 1989-10-26
AT359080B (de) 1980-10-27
BG29571A3 (en) 1980-12-12
NL7801572A (nl) 1978-08-14
IT7848004A0 (it) 1978-02-10
BE863792A (fr) 1978-08-09
GR66187B (el) 1981-01-21
ATA92578A (de) 1980-03-15
BG29646A2 (en) 1981-01-15
IT1102355B (it) 1985-10-07
SU1097622A1 (ru) 1984-06-15
AU516765B2 (en) 1981-06-18
SE7801403L (sv) 1978-08-11
DE2805769A1 (de) 1978-08-17
IL54011A0 (en) 1978-04-30
PL112570B1 (en) 1980-10-31
JPH0140027B2 (el) 1989-08-24
PT67637B (pt) 1979-09-20
CS207603B2 (en) 1981-08-31
US4216221A (en) 1980-08-05
DD134097A5 (de) 1979-02-07
PT67637A (pt) 1978-03-01
HU176033B (en) 1980-11-28
IL54011A (en) 1981-05-20
FI780384A (fi) 1978-08-11
CA1078858A (en) 1980-06-03
JPS53101366A (en) 1978-09-04
NO780431L (no) 1978-08-11
OA05883A (fr) 1981-05-31
DK57778A (da) 1978-08-11
SU936810A3 (ru) 1982-06-15

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