ZA785488B - Novel cyclopeptides - Google Patents

Novel cyclopeptides

Info

Publication number
ZA785488B
ZA785488B ZA00785488A ZA785488A ZA785488B ZA 785488 B ZA785488 B ZA 785488B ZA 00785488 A ZA00785488 A ZA 00785488A ZA 785488 A ZA785488 A ZA 785488A ZA 785488 B ZA785488 B ZA 785488B
Authority
ZA
South Africa
Prior art keywords
novel cyclopeptides
cyclopeptides
novel
Prior art date
Application number
ZA00785488A
Other languages
English (en)
Inventor
H Rink
P Sieber
B Kamber
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of ZA785488B publication Critical patent/ZA785488B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ZA00785488A 1977-09-28 1978-09-27 Novel cyclopeptides ZA785488B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU78191A LU78191A1 (de) 1977-09-28 1977-09-28 Verfahren zur herstellung von neuen cyclopeptiden

Publications (1)

Publication Number Publication Date
ZA785488B true ZA785488B (en) 1979-09-26

Family

ID=19728716

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00785488A ZA785488B (en) 1977-09-28 1978-09-27 Novel cyclopeptides

Country Status (18)

Country Link
US (1) US4238481A (show.php)
EP (1) EP0001295B1 (show.php)
JP (1) JPS5459293A (show.php)
AT (1) AT370090B (show.php)
AU (1) AU523050B2 (show.php)
CA (1) CA1111841A (show.php)
DD (1) DD140142A5 (show.php)
DE (1) DE2861672D1 (show.php)
DK (1) DK151034C (show.php)
ES (1) ES473677A1 (show.php)
FI (1) FI68246C (show.php)
HU (1) HU184612B (show.php)
IE (1) IE47380B1 (show.php)
IL (1) IL55643A (show.php)
LU (1) LU78191A1 (show.php)
NO (1) NO148957C (show.php)
NZ (1) NZ188517A (show.php)
ZA (1) ZA785488B (show.php)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4328214A (en) * 1979-07-04 1982-05-04 Ciba-Geigy Corporation Cyclopeptides and pharmaceutical preparations thereof and also processes for their manufacture
NZ195303A (en) * 1979-10-31 1984-10-19 Merck & Co Inc Cyclic hexapeptide somatostatin analogues,and pharmaceutical compositions
US4369179A (en) * 1979-12-14 1983-01-18 Ciba-Geigy Corporation Acylpeptides
DD155985A5 (de) * 1979-12-21 1982-07-21 Ciba Geigy Ag Verfahren zur herstellung cyclischr octapeptide
US4360516A (en) * 1981-04-13 1982-11-23 Merck & Co., Inc. Modified D-retro cyclic hexapeptide somatostatin analogs
EP0083305B1 (de) * 1981-12-24 1985-07-10 Ciba-Geigy Ag Cyclische Octapeptide und pharmazeutische Präparate davon, sowie Verfahren zur Herstellung derselben und ihre Anwendung
HUT42101A (en) * 1985-01-07 1987-06-29 Sandoz Ag Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds
US4798821A (en) * 1987-03-02 1989-01-17 Merck & Co., Inc. Antihypertensive therapy for diabetics
DE3822557C2 (de) * 1987-07-10 1998-07-02 Ciba Geigy Ag Arzneimittel, enthaltend Somatostatine
US5633263A (en) * 1989-04-26 1997-05-27 The Administrators Of The Tulane Educational Fund Linear somatostatin analogs
JP2882679B2 (ja) * 1989-04-26 1999-04-12 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 線状ソマトスタチン類似体
US5504069A (en) * 1993-02-11 1996-04-02 Biomeasure, Inc. Inhibition of trauma-induced tumor growth
US5597894A (en) * 1995-06-05 1997-01-28 The Louisiana State University Medical Center Foundation Multi-tyrosinated somatostatin analogs
RU2177006C2 (ru) * 1995-09-29 2001-12-20 Биомежер Инкорпорэйтед Циклические пептидные аналоги соматостатина
US7026289B2 (en) * 1997-05-13 2006-04-11 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Method and compositions for treating hyperlipidemia and other conditions
EP0980253B1 (en) * 1997-05-13 2004-03-31 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Somatostatin and somatostatin agonists for treating insulin insensitivity and syndrome x
DE69816808T2 (de) * 1997-05-13 2004-04-15 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Somatostatin agoniste zur reduzierung von körpergewicht
US6004928A (en) * 1997-05-13 1999-12-21 Biomeasure, Incorporated Method of treating hyperlipidemia
US5968903A (en) * 1998-05-07 1999-10-19 Biomeasure, Incorporated Inhibition of H. pylori proliferation
MXPA03011321A (es) 2001-06-08 2004-12-06 Conseils De Rech S Et D Aplica Analogos quimericos de somatostatina-dopamina.
US20040249121A1 (en) * 2003-04-07 2004-12-09 Avi Tovi Process for production of cyclic peptides
EP2662087A1 (en) 2003-04-22 2013-11-13 Ipsen Pharma Somatostatin vectors
WO2009150469A2 (en) 2008-06-12 2009-12-17 Syntaxin Limited Suppression of neuroendocrine diseases
JP5799397B2 (ja) 2008-06-12 2015-10-28 イプセン・バイオイノベーション・リミテッドＩｐｓｅｎ Ｂｉｏｉｎｎｏｖａｔｉｏｎ Ｌｉｍｉｔｅｄ 癌の抑制
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
JP6100699B2 (ja) 2010-12-22 2017-03-22 ザ ソルク インスティテュート フォー バイオロジカル スタディーズ 環状ｃｒｆアンタゴニストペプチド及びその薬学的に許容される塩
ES2862125T3 (es) 2013-06-13 2021-10-07 Antisense Therapeutics Ltd Terapia combinada para acromegalia
TW202540153A (zh) 2023-12-15 2025-10-16 美商紐羅克里生物科學有限公司 脂肪酸結合環肽
TW202544027A (zh) 2024-04-19 2025-11-16 美商紐羅克里生物科學有限公司 促皮質素釋放因子受體２（ｃｒｆｒ２）促效劑

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4011182A (en) * 1975-03-21 1977-03-08 American Home Products Corporation Cyclic undecapeptide analogs of somatostatin and intermediates
US4000259A (en) * 1975-06-16 1976-12-28 American Home Products Corporation Cyclic dodecapeptide analogs of somatostatin and intermediates
NL7607987A (nl) * 1975-08-08 1977-02-10 Merck & Co Inc Werkwijze voor het bereiden van peptiden.
US3988304A (en) * 1975-08-25 1976-10-26 American Home Products Corporation Cyclic dodecapeptide derivatives of somatostatin and intermediates thereof
US4133805A (en) * 1975-12-16 1979-01-09 American Home Products Corporation Cyclic undecapeptides related to somatostatin and intermediates therefor
US4054558A (en) * 1976-05-24 1977-10-18 American Home Products Corporation Cyclic dodecapeptide and intermediates therefor
IE47421B1 (en) * 1977-06-08 1984-03-07 Merck & Co Inc Somatostatin analogs,process for their preparation and pharmaceutical compositions containing them
US4115554A (en) * 1977-08-29 1978-09-19 Merck & Co., Inc. Somatostatin analogs

Also Published As

Publication number Publication date
DK428478A (da) 1979-03-29
EP0001295A3 (en) 1979-06-13
DK151034C (da) 1988-02-22
NZ188517A (en) 1981-04-24
FI68246B (fi) 1985-04-30
EP0001295B1 (de) 1982-03-17
AT370090B (de) 1983-02-25
IE781931L (en) 1979-03-28
IL55643A (en) 1981-12-31
DE2861672D1 (en) 1982-04-15
JPS5459293A (en) 1979-05-12
NO783268L (no) 1979-03-29
IL55643A0 (en) 1978-12-17
LU78191A1 (de) 1979-05-25
AU523050B2 (en) 1982-07-08
NO148957C (no) 1984-01-18
DK151034B (da) 1987-10-12
IE47380B1 (en) 1984-03-07
ES473677A1 (es) 1980-05-16
FI782907A7 (fi) 1979-03-29
JPS6218560B2 (show.php) 1987-04-23
AU4022978A (en) 1980-04-03
EP0001295A2 (de) 1979-04-04
CA1111841A (en) 1981-11-03
ATA698278A (de) 1982-07-15
NO148957B (no) 1983-10-10
FI68246C (fi) 1985-08-12
HU184612B (en) 1984-09-28
US4238481A (en) 1980-12-09
DD140142A5 (de) 1980-02-13

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