ZA785488B - Novel cyclopeptides - Google Patents

Novel cyclopeptides

Info

Publication number
ZA785488B
ZA785488B ZA00785488A ZA785488A ZA785488B ZA 785488 B ZA785488 B ZA 785488B ZA 00785488 A ZA00785488 A ZA 00785488A ZA 785488 A ZA785488 A ZA 785488A ZA 785488 B ZA785488 B ZA 785488B
Authority
ZA
South Africa
Prior art keywords
novel cyclopeptides
cyclopeptides
novel
Prior art date
Application number
ZA00785488A
Other languages
English (en)
Inventor
H Rink
P Sieber
B Kamber
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of ZA785488B publication Critical patent/ZA785488B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ZA00785488A 1977-09-28 1978-09-27 Novel cyclopeptides ZA785488B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU78191A LU78191A1 (de) 1977-09-28 1977-09-28 Verfahren zur herstellung von neuen cyclopeptiden

Publications (1)

Publication Number Publication Date
ZA785488B true ZA785488B (en) 1979-09-26

Family

ID=19728716

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00785488A ZA785488B (en) 1977-09-28 1978-09-27 Novel cyclopeptides

Country Status (18)

Country Link
US (1) US4238481A (2)
EP (1) EP0001295B1 (2)
JP (1) JPS5459293A (2)
AT (1) AT370090B (2)
AU (1) AU523050B2 (2)
CA (1) CA1111841A (2)
DD (1) DD140142A5 (2)
DE (1) DE2861672D1 (2)
DK (1) DK151034C (2)
ES (1) ES473677A1 (2)
FI (1) FI68246C (2)
HU (1) HU184612B (2)
IE (1) IE47380B1 (2)
IL (1) IL55643A (2)
LU (1) LU78191A1 (2)
NO (1) NO148957C (2)
NZ (1) NZ188517A (2)
ZA (1) ZA785488B (2)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4328214A (en) * 1979-07-04 1982-05-04 Ciba-Geigy Corporation Cyclopeptides and pharmaceutical preparations thereof and also processes for their manufacture
NZ195303A (en) * 1979-10-31 1984-10-19 Merck & Co Inc Cyclic hexapeptide somatostatin analogues,and pharmaceutical compositions
US4369179A (en) * 1979-12-14 1983-01-18 Ciba-Geigy Corporation Acylpeptides
EP0031303A3 (de) * 1979-12-21 1981-11-04 Ciba-Geigy Ag Cyclooctapeptide und pharmazeutische Präparate davon, sowie Verfahren zur Herstellung derselben und ihre Anwendung
US4360516A (en) * 1981-04-13 1982-11-23 Merck & Co., Inc. Modified D-retro cyclic hexapeptide somatostatin analogs
ATE14226T1 (de) * 1981-12-24 1985-07-15 Ciba Geigy Ag Cyclische octapeptide und pharmazeutische praeparate davon, sowie verfahren zur herstellung derselben und ihre anwendung.
HUT42101A (en) * 1985-01-07 1987-06-29 Sandoz Ag Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds
US4798821A (en) * 1987-03-02 1989-01-17 Merck & Co., Inc. Antihypertensive therapy for diabetics
DE3845000C2 (de) * 1987-07-10 1998-11-19 Novartis Ag Anwendung von Octreotid zur Behandlung von Brustkrebs
JP2882679B2 (ja) * 1989-04-26 1999-04-12 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 線状ソマトスタチン類似体
US5633263A (en) * 1989-04-26 1997-05-27 The Administrators Of The Tulane Educational Fund Linear somatostatin analogs
US5504069A (en) * 1993-02-11 1996-04-02 Biomeasure, Inc. Inhibition of trauma-induced tumor growth
US5597894A (en) * 1995-06-05 1997-01-28 The Louisiana State University Medical Center Foundation Multi-tyrosinated somatostatin analogs
RU2177006C2 (ru) * 1995-09-29 2001-12-20 Биомежер Инкорпорэйтед Циклические пептидные аналоги соматостатина
AU7655098A (en) * 1997-05-13 1998-12-08 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Somatostatin and somatostatin agonists for decreasing body weight
ES2216290T3 (es) * 1997-05-13 2004-10-16 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Somatostatina y agonistas de la somatostatina para el tratamiento de insensibilidad a la insulina y de sindrome x.
US6004928A (en) * 1997-05-13 1999-12-21 Biomeasure, Incorporated Method of treating hyperlipidemia
US7026289B2 (en) * 1997-05-13 2006-04-11 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Method and compositions for treating hyperlipidemia and other conditions
US5968903A (en) * 1998-05-07 1999-10-19 Biomeasure, Incorporated Inhibition of H. pylori proliferation
JP3996897B2 (ja) 2001-06-08 2007-10-24 ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス ソマトスタチン−ドーパミンキメラ類似体
DE04759123T1 (de) * 2003-04-07 2005-08-18 Novetide Ltd. Verfahren zur herstellung cyclischer peptide
NZ564694A (en) 2003-04-22 2009-11-27 Sod Conseils Rech Applic Peptide vectors
CA2727082C (en) 2008-06-12 2019-02-26 Syntaxin Limited Fusion proteins for use in suppression of acromegaly
JP5799397B2 (ja) 2008-06-12 2015-10-28 イプセン・バイオイノベーション・リミテッドＩｐｓｅｎ Ｂｉｏｉｎｎｏｖａｔｉｏｎ Ｌｉｍｉｔｅｄ 癌の抑制
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
EP2654772B1 (en) 2010-12-22 2018-09-26 The Salk Institute for Biological Studies Cyclic crf antagonist peptides
EP3007704B1 (en) 2013-06-13 2021-01-06 Antisense Therapeutics Ltd Combination therapy for acromegaly
WO2025128794A1 (en) 2023-12-15 2025-06-19 Neurocrine Biosciences, Inc. Fatty acid conjugated cyclic peptides
TW202544027A (zh) 2024-04-19 2025-11-16 美商紐羅克里生物科學有限公司 促皮質素釋放因子受體２（ｃｒｆｒ２）促效劑
WO2026064495A1 (en) 2024-09-20 2026-03-26 Neurocrine Biosciences, Inc. Chemically modified peptides and use thereof
WO2026064486A1 (en) 2024-09-20 2026-03-26 Neurocrine Biosciences, Inc. Chemically modified peptides and use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4011182A (en) * 1975-03-21 1977-03-08 American Home Products Corporation Cyclic undecapeptide analogs of somatostatin and intermediates
US4000259A (en) * 1975-06-16 1976-12-28 American Home Products Corporation Cyclic dodecapeptide analogs of somatostatin and intermediates
NL7607987A (nl) * 1975-08-08 1977-02-10 Merck & Co Inc Werkwijze voor het bereiden van peptiden.
US3988304A (en) * 1975-08-25 1976-10-26 American Home Products Corporation Cyclic dodecapeptide derivatives of somatostatin and intermediates thereof
US4133805A (en) * 1975-12-16 1979-01-09 American Home Products Corporation Cyclic undecapeptides related to somatostatin and intermediates therefor
US4054558A (en) * 1976-05-24 1977-10-18 American Home Products Corporation Cyclic dodecapeptide and intermediates therefor
IT1105131B (it) * 1977-06-08 1985-10-28 Merck & Co Inc Peptidi analoghi della somatostatina dotati di piu' lunga e maggiore attivita' biologica e relativo procedimento di protezione
US4115554A (en) * 1977-08-29 1978-09-19 Merck & Co., Inc. Somatostatin analogs

Also Published As

Publication number Publication date
DK428478A (da) 1979-03-29
EP0001295A2 (de) 1979-04-04
DD140142A5 (de) 1980-02-13
AT370090B (de) 1983-02-25
HU184612B (en) 1984-09-28
JPS6218560B2 (2) 1987-04-23
DE2861672D1 (en) 1982-04-15
NZ188517A (en) 1981-04-24
NO148957B (no) 1983-10-10
ES473677A1 (es) 1980-05-16
NO783268L (no) 1979-03-29
DK151034C (da) 1988-02-22
IE47380B1 (en) 1984-03-07
EP0001295A3 (en) 1979-06-13
IL55643A (en) 1981-12-31
FI68246C (fi) 1985-08-12
IE781931L (en) 1979-03-28
NO148957C (no) 1984-01-18
CA1111841A (en) 1981-11-03
LU78191A1 (de) 1979-05-25
FI782907A7 (fi) 1979-03-29
AU523050B2 (en) 1982-07-08
JPS5459293A (en) 1979-05-12
EP0001295B1 (de) 1982-03-17
ATA698278A (de) 1982-07-15
AU4022978A (en) 1980-04-03
US4238481A (en) 1980-12-09
DK151034B (da) 1987-10-12
FI68246B (fi) 1985-04-30
IL55643A0 (en) 1978-12-17

Similar Documents

Publication Publication Date Title
ZA785488B (en) Novel cyclopeptides
GB2010944B (en) Sound-absorbingstructures
GB2005266B (en) 4-amino-4-arylcyclohexanols
GB1538356A (en) Polyester-polyimides
JPS53107794A (en) Abraisives
GB2003859A (en) 4-substituted-pyrazoles
JPS53125886A (en) Multicollimator
GB2013704B (en) Lightstick
GB2008935A (en) Coffeebrewer
GB2005568B (en) Electrographicprinter
JPS5416423A (en) Alphaafluoromethyllalphaaaminoalkanoate
JPS53129840A (en) Surgeearrester
GB2008914B (en) Cloches
IL56268A0 (en) 4a-aryl-octahydro-1h-2-pyarinidines
JPS5439050A (en) Phosphorylized nonapeptide
JPS543029A (en) N*nndisubstituted ppphenylendiamine
GB1556977A (en) Psrayer
GB2009167B (en) Benzoxazolyl-phenyl-stilbenes
JPS53116345A (en) Oxylanevarboxyamide
AU3918778A (en) Beta-substituted-diketones
JPS54146342A (en) Wiperrblade
GB2009186B (en) Stailizer
IL56112A0 (en) Imino-bridged benzocycloheptapyridines
JPS53137978A (en) Benzylpyrimidine
GB2004871A (en) Benzodifuranes