ZA783125B - Compounds of the pregnane series with an oxygen function in the 19-position,processes for their manufacture and pharmaceutical preparations containing these compounds - Google Patents

Compounds of the pregnane series with an oxygen function in the 19-position,processes for their manufacture and pharmaceutical preparations containing these compounds

Info

Publication number
ZA783125B
ZA783125B ZA00783125A ZA783125A ZA783125B ZA 783125 B ZA783125 B ZA 783125B ZA 00783125 A ZA00783125 A ZA 00783125A ZA 783125 A ZA783125 A ZA 783125A ZA 783125 B ZA783125 B ZA 783125B
Authority
ZA
South Africa
Prior art keywords
compounds
manufacture
processes
pharmaceutical preparations
preparations containing
Prior art date
Application number
ZA00783125A
Other languages
English (en)
Inventor
M Biollaz
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of ZA783125B publication Critical patent/ZA783125B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C07J33/007—Cyclic thioketals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA00783125A 1977-05-31 1978-05-30 Compounds of the pregnane series with an oxygen function in the 19-position,processes for their manufacture and pharmaceutical preparations containing these compounds ZA783125B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU77457A LU77457A1 (de) 1977-05-31 1977-05-31

Publications (1)

Publication Number Publication Date
ZA783125B true ZA783125B (en) 1979-06-27

Family

ID=19728591

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00783125A ZA783125B (en) 1977-05-31 1978-05-30 Compounds of the pregnane series with an oxygen function in the 19-position,processes for their manufacture and pharmaceutical preparations containing these compounds

Country Status (27)

Country Link
US (1) US4309423A (de)
JP (1) JPS53149964A (de)
AT (1) AT365609B (de)
AU (1) AU520330B2 (de)
BE (1) BE867634A (de)
CA (1) CA1114367A (de)
DD (1) DD140146A5 (de)
DE (1) DE2823239A1 (de)
DK (1) DK240078A (de)
ES (5) ES470282A1 (de)
FI (1) FI781628A (de)
FR (3) FR2405712A1 (de)
GB (1) GB1603675A (de)
GR (1) GR71594B (de)
HU (1) HU181861B (de)
IL (1) IL54805A (de)
IT (1) IT7849581A0 (de)
LU (1) LU77457A1 (de)
NL (1) NL7805632A (de)
NO (1) NO781884L (de)
NZ (1) NZ187431A (de)
PH (1) PH14606A (de)
PL (1) PL207237A1 (de)
PT (1) PT68095A (de)
SE (1) SE7806244L (de)
SU (1) SU786906A3 (de)
ZA (1) ZA783125B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA18433A1 (fr) * 1978-05-26 1979-12-31 Ciba Geigy Ag Procede pour la synthese de la chaine laterale hydroxyacetyle de steroides du type pregnagne, nouveaux 21-hydroxy-20-oxo-17 alpha-pregnagnes et produits pharmaceutiques en renfermant
US4261985A (en) * 1978-11-22 1981-04-14 Ciba-Geigy Corporation Novel diuretics
US5002940A (en) * 1984-11-06 1991-03-26 Ciba-Geigy Corporation Solid drug formulations and stable suspensions
US4659704A (en) * 1985-05-21 1987-04-21 Ramot University Authority For Applied Research & Industrial Development Ltd. 19-hydroxyaldosterone and its preparation
FR2656309B1 (fr) * 1989-12-22 1992-05-07 Roussel Uclaf Nouveaux produits sterouides comportant en position 10, un radical ethyle substitue, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant.
FR2676740B1 (fr) * 1991-05-23 1993-11-05 Roussel Uclaf Nouveaux derives sterouides du pregna-4,9(11),17(20)-trie-3-one, leur preparation, leur application a la preparation de composes sterouides de type pregna-4,9(11),16-triene-3,20-dione et nouveaux intermediaires.
DE4433374A1 (de) * 1994-09-20 1996-03-21 Hoechst Ag 17-Desoxi-corticosteroid-21-/O/-Carbonsäure- ester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE60124289T2 (de) * 2000-09-18 2007-09-06 Applied Research Systems Ars Holding N.V. Verfahren zur herstellung von 21-hydroxy-6,19-oxidoprogesteron (21oh-6op)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1146651B (de) * 1956-07-28 1963-04-04 Giuseppe Giusi Vorschub-Schaltgetriebe fuer Maschinen zum Ausschneiden von runden Scheiben aus Kunststoffplatten, insbesondere Knopfrondellen
US3039926A (en) * 1958-10-10 1962-06-19 Pfizer & Co C 19-hydroxy pregnenes
CH425774A (de) * 1961-07-14 1966-12-15 Ciba Geigy Verfahren zur Herstellung von 19-Nor-steroiden
GB1041534A (en) * 1963-04-24 1966-09-07 Merck & Co Inc 20-spiroxane compounds
US3493564A (en) * 1968-02-29 1970-02-03 American Home Prod 2,19-epoxy-delta**4,6-steroids and intermediates for their synthesis
BR6915132D0 (pt) * 1969-04-02 1973-02-08 Ciba Geigy Processo para a obtencao de delta 4 6-ou delta 5(10) 6-3-oxo-19-nor-esteroides
US3849404A (en) * 1973-03-09 1974-11-19 Searle & Co Purification of 6,7-dihydro-17-hydroxy-3-oxo-3'h-cyclopropa(6,7)-17alpha-pregna-4,6-diene-21-carboxylic acid gamma-lactones
CA1049498A (en) * 1973-11-29 1979-02-27 Gunther Kruger Steroid compounds and processes therefor
JPS53116361A (en) * 1977-03-17 1978-10-11 Mitsubishi Chem Ind Ltd Preparation of 7 acylthioo44enee33oxosteroid

Also Published As

Publication number Publication date
PH14606A (en) 1981-10-02
ATA393178A (de) 1981-06-15
PL207237A1 (pl) 1979-06-04
IL54805A (en) 1982-11-30
AU3665078A (en) 1979-12-06
FR2405958B1 (de) 1982-01-15
FR2405712B1 (de) 1982-09-10
DD140146A5 (de) 1980-02-13
CA1114367A (en) 1981-12-15
DK240078A (da) 1978-12-01
AT365609B (de) 1982-02-10
GB1603675A (en) 1981-11-25
FR2408623A1 (fr) 1979-06-08
IT7849581A0 (it) 1978-05-29
AU520330B2 (en) 1982-01-28
FR2405958A1 (fr) 1979-05-11
NZ187431A (en) 1980-05-27
GR71594B (de) 1983-06-17
ES478127A1 (es) 1979-05-16
SE7806244L (sv) 1978-12-01
NL7805632A (nl) 1978-12-04
FR2408623B1 (de) 1982-03-05
BE867634A (fr) 1978-11-30
FR2405712A1 (fr) 1979-05-11
FI781628A (fi) 1978-12-01
LU77457A1 (de) 1979-01-19
ES478125A1 (es) 1979-05-16
ES478128A1 (es) 1979-05-16
SU786906A3 (ru) 1980-12-07
PT68095A (de) 1978-06-01
HU181861B (en) 1983-11-28
ES478126A1 (es) 1979-05-16
ES470282A1 (es) 1979-09-16
IL54805A0 (en) 1978-07-31
NO781884L (no) 1978-12-01
JPS53149964A (en) 1978-12-27
DE2823239A1 (de) 1978-12-14
US4309423A (en) 1982-01-05

Similar Documents

Publication Publication Date Title
DE2861809D1 (en) Corticoids-17-alkylcarbonates, process for their preparation and preparations containing them
JPS5248289A (en) Input means into blood
JPS52122632A (en) Medical composition and process for preparing same
IL53063A (en) Phenoxy-amino-propanols,processes for their preparation and pharmaceutical compositions comprising them
IL53353A (en) Spirolactones,process for their preparation and pharmaceutical compositions containing them
IL51816A (en) Steroids,their preparation and pharmaceutical compositions containing them
GR61176B (en) Pharmaceutical compositions and process for the preparation thereof
DE3071385D1 (en) Antiinflammatory 5-substituted-2,3-diaryl-thiophenes, processes for their preparation and pharmaceutical compositions containing them
GB1544647A (en) 2-piperidinoalkyl-1-benzofurans-1,4-benzodioxans and 1,4-benzoxathians process for their manufacture and pharmaceutical preparations containing them
GR63669B (en) Process of dose reduction of one biological drastic substance although conserve the biological influenier
ZA765817B (en) Biological preparations
GB1534351A (en) Indolylalkylpiperidines process for their manufacture and pharmaceutical preparations containing them
ZA783125B (en) Compounds of the pregnane series with an oxygen function in the 19-position,processes for their manufacture and pharmaceutical preparations containing these compounds
AU503003B2 (en) Active carbon and preparation thereof
IL51586A (en) 3-oxo-17 beta-hydroxy-17 alpha-hydroxypropyl androstane and estrane derivatives,process for their preparation and pharmaceutical preparations containing them
AU8176175A (en) Pyrazolobenzazepines, process for their manufacture and pharmaceutical preparations containing them
AU8760075A (en) 3-fluorobenzodia zepines and processes for their preparation
IL49356A0 (en) Method for the chemical modification of proteins,substances used in this method and their preparation
ZA763138B (en) Stable solutions and processes for their preparations
IL53552A (en) 1-piperazinopropanol esters,their preparation and pharmaceutical compositions containing them
DE2861477D1 (en) (omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances
GR60560B (en) Penicillines,preparation process and use thereof as medicines
IL53030A (en) Derivatives of 9-chloroprednisolone,processes for their preparation and pharmaceutical compositions containing the same
ZA785599B (en) New piperazinopyrrolobenzodiazepines,process for their manufacture and pharmaceutical preparations containing them
DE2860317D1 (en) Medicines with sulfur containing esters, and their preparation