ES478126A1 - Procedimiento para la obtencion de compuestos esteroides de la serie pregnano. - Google Patents
Procedimiento para la obtencion de compuestos esteroides de la serie pregnano.Info
- Publication number
- ES478126A1 ES478126A1 ES478126A ES478126A ES478126A1 ES 478126 A1 ES478126 A1 ES 478126A1 ES 478126 A ES478126 A ES 478126A ES 478126 A ES478126 A ES 478126A ES 478126 A1 ES478126 A1 ES 478126A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- manufacture
- processes
- pregnane series
- pharmaceutical preparations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
- C07J33/007—Cyclic thioketals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
- C07J5/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
Abstract
Procedimiento para la obtención de compuestos esteroides de la serie pregnano, oxigenados en la posición 19 de fórmula I *** Donde R1 significa un átomo de hidrógeno y R2 significa un grupo alcanoiltio inferior alpha-orientado, ó R1 y R2 juntos significan un enlace carbono-carbono, R3 significa un grupo hidroximetilo libre o esterificado por un alcancilo inferior, y R4 significa un átomo de hidrógeno o el resto acilo de un ácido carboxílico Ac.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU77457A LU77457A1 (es) | 1977-05-31 | 1977-05-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES478126A1 true ES478126A1 (es) | 1979-05-16 |
Family
ID=19728591
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES470282A Expired ES470282A1 (es) | 1977-05-31 | 1978-05-29 | Procedimiento para la obtencion de compuestos esteroides de la serie pregnano |
ES478126A Expired ES478126A1 (es) | 1977-05-31 | 1979-02-27 | Procedimiento para la obtencion de compuestos esteroides de la serie pregnano. |
ES478128A Expired ES478128A1 (es) | 1977-05-31 | 1979-02-27 | Procedimiento para la obtencion de compuestos esteroides de la serie pregnano. |
ES478125A Expired ES478125A1 (es) | 1977-05-31 | 1979-02-27 | Procedimiento para la obtencion de compuestos esteroides de la serie pregnano. |
ES478127A Expired ES478127A1 (es) | 1977-05-31 | 1979-02-27 | Procedimiento para la obtencion de compuestos esteroides de la serie pregnano. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES470282A Expired ES470282A1 (es) | 1977-05-31 | 1978-05-29 | Procedimiento para la obtencion de compuestos esteroides de la serie pregnano |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES478128A Expired ES478128A1 (es) | 1977-05-31 | 1979-02-27 | Procedimiento para la obtencion de compuestos esteroides de la serie pregnano. |
ES478125A Expired ES478125A1 (es) | 1977-05-31 | 1979-02-27 | Procedimiento para la obtencion de compuestos esteroides de la serie pregnano. |
ES478127A Expired ES478127A1 (es) | 1977-05-31 | 1979-02-27 | Procedimiento para la obtencion de compuestos esteroides de la serie pregnano. |
Country Status (27)
Country | Link |
---|---|
US (1) | US4309423A (es) |
JP (1) | JPS53149964A (es) |
AT (1) | AT365609B (es) |
AU (1) | AU520330B2 (es) |
BE (1) | BE867634A (es) |
CA (1) | CA1114367A (es) |
DD (1) | DD140146A5 (es) |
DE (1) | DE2823239A1 (es) |
DK (1) | DK240078A (es) |
ES (5) | ES470282A1 (es) |
FI (1) | FI781628A (es) |
FR (3) | FR2405712A1 (es) |
GB (1) | GB1603675A (es) |
GR (1) | GR71594B (es) |
HU (1) | HU181861B (es) |
IL (1) | IL54805A (es) |
IT (1) | IT7849581A0 (es) |
LU (1) | LU77457A1 (es) |
NL (1) | NL7805632A (es) |
NO (1) | NO781884L (es) |
NZ (1) | NZ187431A (es) |
PH (1) | PH14606A (es) |
PL (1) | PL207237A1 (es) |
PT (1) | PT68095A (es) |
SE (1) | SE7806244L (es) |
SU (1) | SU786906A3 (es) |
ZA (1) | ZA783125B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MA18433A1 (fr) * | 1978-05-26 | 1979-12-31 | Ciba Geigy Ag | Procede pour la synthese de la chaine laterale hydroxyacetyle de steroides du type pregnagne, nouveaux 21-hydroxy-20-oxo-17 alpha-pregnagnes et produits pharmaceutiques en renfermant |
US4261985A (en) * | 1978-11-22 | 1981-04-14 | Ciba-Geigy Corporation | Novel diuretics |
US5002940A (en) * | 1984-11-06 | 1991-03-26 | Ciba-Geigy Corporation | Solid drug formulations and stable suspensions |
US4659704A (en) * | 1985-05-21 | 1987-04-21 | Ramot University Authority For Applied Research & Industrial Development Ltd. | 19-hydroxyaldosterone and its preparation |
FR2656309B1 (fr) * | 1989-12-22 | 1992-05-07 | Roussel Uclaf | Nouveaux produits sterouides comportant en position 10, un radical ethyle substitue, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant. |
FR2676740B1 (fr) * | 1991-05-23 | 1993-11-05 | Roussel Uclaf | Nouveaux derives sterouides du pregna-4,9(11),17(20)-trie-3-one, leur preparation, leur application a la preparation de composes sterouides de type pregna-4,9(11),16-triene-3,20-dione et nouveaux intermediaires. |
DE4433374A1 (de) * | 1994-09-20 | 1996-03-21 | Hoechst Ag | 17-Desoxi-corticosteroid-21-/O/-Carbonsäure- ester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
DE60124289T2 (de) * | 2000-09-18 | 2007-09-06 | Applied Research Systems Ars Holding N.V. | Verfahren zur herstellung von 21-hydroxy-6,19-oxidoprogesteron (21oh-6op) |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1146651B (de) * | 1956-07-28 | 1963-04-04 | Giuseppe Giusi | Vorschub-Schaltgetriebe fuer Maschinen zum Ausschneiden von runden Scheiben aus Kunststoffplatten, insbesondere Knopfrondellen |
US3039926A (en) * | 1958-10-10 | 1962-06-19 | Pfizer & Co C | 19-hydroxy pregnenes |
CH425774A (de) * | 1961-07-14 | 1966-12-15 | Ciba Geigy | Verfahren zur Herstellung von 19-Nor-steroiden |
GB1041534A (en) * | 1963-04-24 | 1966-09-07 | Merck & Co Inc | 20-spiroxane compounds |
US3493564A (en) * | 1968-02-29 | 1970-02-03 | American Home Prod | 2,19-epoxy-delta**4,6-steroids and intermediates for their synthesis |
BR6915132D0 (pt) * | 1969-04-02 | 1973-02-08 | Ciba Geigy | Processo para a obtencao de delta 4 6-ou delta 5(10) 6-3-oxo-19-nor-esteroides |
US3849404A (en) * | 1973-03-09 | 1974-11-19 | Searle & Co | Purification of 6,7-dihydro-17-hydroxy-3-oxo-3'h-cyclopropa(6,7)-17alpha-pregna-4,6-diene-21-carboxylic acid gamma-lactones |
CA1049498A (en) * | 1973-11-29 | 1979-02-27 | Gunther Kruger | Steroid compounds and processes therefor |
JPS53116361A (en) * | 1977-03-17 | 1978-10-11 | Mitsubishi Chem Ind Ltd | Preparation of 7 acylthioo44enee33oxosteroid |
-
1977
- 1977-05-31 LU LU77457A patent/LU77457A1/xx unknown
-
1978
- 1978-05-23 FI FI781628A patent/FI781628A/fi not_active Application Discontinuation
- 1978-05-24 NL NL7805632A patent/NL7805632A/xx not_active Application Discontinuation
- 1978-05-26 FR FR7815730A patent/FR2405712A1/fr active Granted
- 1978-05-27 DE DE19782823239 patent/DE2823239A1/de not_active Withdrawn
- 1978-05-29 GR GR56369A patent/GR71594B/el unknown
- 1978-05-29 PT PT68095A patent/PT68095A/pt unknown
- 1978-05-29 IT IT7849581A patent/IT7849581A0/it unknown
- 1978-05-29 SU SU782618095A patent/SU786906A3/ru active
- 1978-05-29 ES ES470282A patent/ES470282A1/es not_active Expired
- 1978-05-29 IL IL54805A patent/IL54805A/xx unknown
- 1978-05-29 DD DD78205642A patent/DD140146A5/de unknown
- 1978-05-30 HU HU78CI1833A patent/HU181861B/hu unknown
- 1978-05-30 SE SE7806244A patent/SE7806244L/xx unknown
- 1978-05-30 GB GB24445/78A patent/GB1603675A/en not_active Expired
- 1978-05-30 DK DK240078A patent/DK240078A/da unknown
- 1978-05-30 NO NO78781884A patent/NO781884L/no unknown
- 1978-05-30 ZA ZA00783125A patent/ZA783125B/xx unknown
- 1978-05-30 AT AT0393178A patent/AT365609B/de not_active IP Right Cessation
- 1978-05-30 BE BE188175A patent/BE867634A/xx not_active IP Right Cessation
- 1978-05-30 AU AU36650/78A patent/AU520330B2/en not_active Expired
- 1978-05-30 NZ NZ187431A patent/NZ187431A/xx unknown
- 1978-05-31 PL PL20723778A patent/PL207237A1/xx unknown
- 1978-05-31 JP JP6443978A patent/JPS53149964A/ja active Pending
- 1978-05-31 CA CA304,525A patent/CA1114367A/en not_active Expired
- 1978-06-20 PH PH21285A patent/PH14606A/en unknown
- 1978-11-23 FR FR7833067A patent/FR2405958A1/fr active Granted
- 1978-11-23 FR FR7833066A patent/FR2408623A1/fr active Granted
-
1979
- 1979-02-27 ES ES478126A patent/ES478126A1/es not_active Expired
- 1979-02-27 ES ES478128A patent/ES478128A1/es not_active Expired
- 1979-02-27 ES ES478125A patent/ES478125A1/es not_active Expired
- 1979-02-27 ES ES478127A patent/ES478127A1/es not_active Expired
-
1980
- 1980-02-08 US US06/119,702 patent/US4309423A/en not_active Expired - Lifetime
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