JPS53149964A - Pregnane systme compound having oxygen functionality in 199position process for preparing same and medical formulation containing same - Google Patents

Pregnane systme compound having oxygen functionality in 199position process for preparing same and medical formulation containing same

Info

Publication number
JPS53149964A
JPS53149964A JP6443978A JP6443978A JPS53149964A JP S53149964 A JPS53149964 A JP S53149964A JP 6443978 A JP6443978 A JP 6443978A JP 6443978 A JP6443978 A JP 6443978A JP S53149964 A JPS53149964 A JP S53149964A
Authority
JP
Japan
Prior art keywords
same
systme
pregnane
compound
formulation containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6443978A
Other languages
English (en)
Inventor
Biora Mishieru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of JPS53149964A publication Critical patent/JPS53149964A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C07J33/007—Cyclic thioketals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JP6443978A 1977-05-31 1978-05-31 Pregnane systme compound having oxygen functionality in 199position process for preparing same and medical formulation containing same Pending JPS53149964A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU77457A LU77457A1 (ja) 1977-05-31 1977-05-31

Publications (1)

Publication Number Publication Date
JPS53149964A true JPS53149964A (en) 1978-12-27

Family

ID=19728591

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6443978A Pending JPS53149964A (en) 1977-05-31 1978-05-31 Pregnane systme compound having oxygen functionality in 199position process for preparing same and medical formulation containing same

Country Status (27)

Country Link
US (1) US4309423A (ja)
JP (1) JPS53149964A (ja)
AT (1) AT365609B (ja)
AU (1) AU520330B2 (ja)
BE (1) BE867634A (ja)
CA (1) CA1114367A (ja)
DD (1) DD140146A5 (ja)
DE (1) DE2823239A1 (ja)
DK (1) DK240078A (ja)
ES (5) ES470282A1 (ja)
FI (1) FI781628A (ja)
FR (3) FR2405712A1 (ja)
GB (1) GB1603675A (ja)
GR (1) GR71594B (ja)
HU (1) HU181861B (ja)
IL (1) IL54805A (ja)
IT (1) IT7849581A0 (ja)
LU (1) LU77457A1 (ja)
NL (1) NL7805632A (ja)
NO (1) NO781884L (ja)
NZ (1) NZ187431A (ja)
PH (1) PH14606A (ja)
PL (1) PL207237A1 (ja)
PT (1) PT68095A (ja)
SE (1) SE7806244L (ja)
SU (1) SU786906A3 (ja)
ZA (1) ZA783125B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA18433A1 (fr) * 1978-05-26 1979-12-31 Ciba Geigy Ag Procede pour la synthese de la chaine laterale hydroxyacetyle de steroides du type pregnagne, nouveaux 21-hydroxy-20-oxo-17 alpha-pregnagnes et produits pharmaceutiques en renfermant
US4261985A (en) * 1978-11-22 1981-04-14 Ciba-Geigy Corporation Novel diuretics
US5002940A (en) * 1984-11-06 1991-03-26 Ciba-Geigy Corporation Solid drug formulations and stable suspensions
US4659704A (en) * 1985-05-21 1987-04-21 Ramot University Authority For Applied Research & Industrial Development Ltd. 19-hydroxyaldosterone and its preparation
FR2656309B1 (fr) * 1989-12-22 1992-05-07 Roussel Uclaf Nouveaux produits sterouides comportant en position 10, un radical ethyle substitue, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant.
FR2676740B1 (fr) * 1991-05-23 1993-11-05 Roussel Uclaf Nouveaux derives sterouides du pregna-4,9(11),17(20)-trie-3-one, leur preparation, leur application a la preparation de composes sterouides de type pregna-4,9(11),16-triene-3,20-dione et nouveaux intermediaires.
DE4433374A1 (de) * 1994-09-20 1996-03-21 Hoechst Ag 17-Desoxi-corticosteroid-21-/O/-Carbonsäure- ester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE60124289T2 (de) * 2000-09-18 2007-09-06 Applied Research Systems Ars Holding N.V. Verfahren zur herstellung von 21-hydroxy-6,19-oxidoprogesteron (21oh-6op)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1146651B (de) * 1956-07-28 1963-04-04 Giuseppe Giusi Vorschub-Schaltgetriebe fuer Maschinen zum Ausschneiden von runden Scheiben aus Kunststoffplatten, insbesondere Knopfrondellen
US3039926A (en) * 1958-10-10 1962-06-19 Pfizer & Co C 19-hydroxy pregnenes
CH425774A (de) * 1961-07-14 1966-12-15 Ciba Geigy Verfahren zur Herstellung von 19-Nor-steroiden
GB1041534A (en) * 1963-04-24 1966-09-07 Merck & Co Inc 20-spiroxane compounds
US3493564A (en) * 1968-02-29 1970-02-03 American Home Prod 2,19-epoxy-delta**4,6-steroids and intermediates for their synthesis
BR6915132D0 (pt) * 1969-04-02 1973-02-08 Ciba Geigy Processo para a obtencao de delta 4 6-ou delta 5(10) 6-3-oxo-19-nor-esteroides
US3849404A (en) * 1973-03-09 1974-11-19 Searle & Co Purification of 6,7-dihydro-17-hydroxy-3-oxo-3'h-cyclopropa(6,7)-17alpha-pregna-4,6-diene-21-carboxylic acid gamma-lactones
CA1049498A (en) * 1973-11-29 1979-02-27 Gunther Kruger Steroid compounds and processes therefor
JPS53116361A (en) * 1977-03-17 1978-10-11 Mitsubishi Chem Ind Ltd Preparation of 7 acylthioo44enee33oxosteroid

Also Published As

Publication number Publication date
ATA393178A (de) 1981-06-15
GB1603675A (en) 1981-11-25
FR2405958B1 (ja) 1982-01-15
LU77457A1 (ja) 1979-01-19
NO781884L (no) 1978-12-01
HU181861B (en) 1983-11-28
US4309423A (en) 1982-01-05
ZA783125B (en) 1979-06-27
FR2405712A1 (fr) 1979-05-11
FR2405712B1 (ja) 1982-09-10
IL54805A (en) 1982-11-30
IT7849581A0 (it) 1978-05-29
CA1114367A (en) 1981-12-15
AU3665078A (en) 1979-12-06
ES478127A1 (es) 1979-05-16
BE867634A (fr) 1978-11-30
NL7805632A (nl) 1978-12-04
DE2823239A1 (de) 1978-12-14
AT365609B (de) 1982-02-10
SE7806244L (sv) 1978-12-01
NZ187431A (en) 1980-05-27
ES470282A1 (es) 1979-09-16
FR2408623A1 (fr) 1979-06-08
AU520330B2 (en) 1982-01-28
FR2405958A1 (fr) 1979-05-11
DK240078A (da) 1978-12-01
FR2408623B1 (ja) 1982-03-05
PH14606A (en) 1981-10-02
ES478126A1 (es) 1979-05-16
ES478125A1 (es) 1979-05-16
SU786906A3 (ru) 1980-12-07
FI781628A (fi) 1978-12-01
GR71594B (ja) 1983-06-17
ES478128A1 (es) 1979-05-16
PT68095A (de) 1978-06-01
IL54805A0 (en) 1978-07-31
DD140146A5 (de) 1980-02-13
PL207237A1 (pl) 1979-06-04

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