ZA74509B - 6-(amidino-and imidoylaminoalkanoylamino)aracylamino penicillanic acids and their preparation - Google Patents

6-(amidino-and imidoylaminoalkanoylamino)aracylamino penicillanic acids and their preparation

Info

Publication number
ZA74509B
ZA74509B ZA740509A ZA74509A ZA74509B ZA 74509 B ZA74509 B ZA 74509B ZA 740509 A ZA740509 A ZA 740509A ZA 74509 A ZA74509 A ZA 74509A ZA 74509 B ZA74509 B ZA 74509B
Authority
ZA
South Africa
Prior art keywords
imidoylaminoalkanoylamino
aracylamino
amidino
preparation
penicillanic acids
Prior art date
Application number
ZA740509A
Other languages
English (en)
Inventor
E Hamanakak
J Stam
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/424,891 external-priority patent/US3951952A/en
Application filed by Pfizer filed Critical Pfizer
Publication of ZA74509B publication Critical patent/ZA74509B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/881Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with a hydrogen atom or an unsubstituted hydrocarbon radical, attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA740509A 1973-12-14 1974-01-24 6-(amidino-and imidoylaminoalkanoylamino)aracylamino penicillanic acids and their preparation ZA74509B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/424,891 US3951952A (en) 1972-08-02 1973-12-14 Broad spectrum antibiotics

Publications (1)

Publication Number Publication Date
ZA74509B true ZA74509B (en) 1974-12-24

Family

ID=23684297

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA740509A ZA74509B (en) 1973-12-14 1974-01-24 6-(amidino-and imidoylaminoalkanoylamino)aracylamino penicillanic acids and their preparation

Country Status (31)

Country Link
US (1) US4073783A (nl)
JP (3) JPS5089393A (nl)
KR (1) KR780000354B1 (nl)
AR (1) AR202472A1 (nl)
AT (1) AT326821B (nl)
BE (1) BE810266R (nl)
BG (1) BG24955A3 (nl)
CA (1) CA1023348A (nl)
CH (1) CH596218A5 (nl)
CS (1) CS194205B2 (nl)
DD (1) DD113008A6 (nl)
DE (1) DE2403512C2 (nl)
DK (1) DK150856C (nl)
EG (1) EG11025A (nl)
ES (1) ES422732A2 (nl)
FI (1) FI62840C (nl)
FR (1) FR2254310B2 (nl)
GB (1) GB1462421A (nl)
HU (1) HU167158B (nl)
IE (1) IE39964B1 (nl)
IL (1) IL44033A (nl)
IN (1) IN139932B (nl)
LU (1) LU69290A1 (nl)
NL (1) NL7401174A (nl)
NO (1) NO145794C (nl)
PH (1) PH15634A (nl)
RO (1) RO67596A (nl)
SE (1) SE421797B (nl)
SU (1) SU609468A3 (nl)
YU (1) YU22674A (nl)
ZA (1) ZA74509B (nl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024130A (en) * 1975-03-31 1977-05-17 Pfizer Inc. Process for the manufacture of alkali metal salts of 6-[2-phenyl-2-(imidoylaminoalkanoylamino)acetamido]penicillanic acids
US4168266A (en) * 1978-05-30 1979-09-18 E. R. Squibb & Sons, Inc. 6-[[[(2-Cyanomethyl)amino]-1,2-dioxoethyl]-amino]acyl penicillins
CN102190598B (zh) * 2011-03-28 2014-01-29 浙江工业大学 环丙烷肟酯衍生物及其制备方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3634405A (en) * 1969-08-01 1972-01-11 Bristol Myers Co Synthetic penicillins
US3579501A (en) * 1969-08-22 1971-05-18 Bristol Myers Co 6-(alpha-(3 - guanyl - 1 - ureido)phenyl- or thienyl-acetamido)penicillanic acids
DE2104580C3 (de) * 1971-02-01 1981-04-02 Bayer Ag, 5090 Leverkusen Acylureidopenicilline
BE790441A (fr) * 1971-10-23 1973-04-24 Bayer Ag Nouvelles penicillines, leur procede de preparation et medicament les contenant
BE794886A (fr) * 1972-02-22 1973-08-02 Pfizer Acides 6-(alpha-(omega-guanidinoalcanoylamino)acylamino)-penicillaniques
US3838153A (en) * 1972-05-16 1974-09-24 Pfizer 6-(alpha-(guanylureidoalkanoylamino)aracylamino)penicillanic acids

Also Published As

Publication number Publication date
FR2254310A2 (nl) 1975-07-11
NO145794B (no) 1982-02-22
DE2403512C2 (de) 1983-01-13
RO67596A (ro) 1980-02-15
FI62840C (fi) 1983-03-10
JPS5089393A (nl) 1975-07-17
SU609468A3 (ru) 1978-05-30
JPS6043072B2 (ja) 1985-09-26
DE2403512A1 (de) 1975-06-19
YU22674A (en) 1982-02-28
SE7400501L (nl) 1975-06-16
US4073783A (en) 1978-02-14
LU69290A1 (nl) 1974-09-25
FR2254310B2 (nl) 1977-04-22
JPS5756483A (en) 1982-04-05
BG24955A3 (en) 1978-06-15
CS194205B2 (en) 1979-11-30
AT326821B (de) 1975-12-29
JPS6048519B2 (ja) 1985-10-28
DK150856B (da) 1987-07-06
CA1023348A (en) 1977-12-27
DK45574A (nl) 1975-08-11
IN139932B (nl) 1976-08-21
IE39964B1 (en) 1979-02-14
IE39964L (en) 1975-06-14
FI740226A0 (nl) 1975-06-15
SE421797B (sv) 1982-02-01
HU167158B (nl) 1975-08-28
BE810266R (fr) 1974-07-29
ATA73374A (de) 1975-03-15
PH15634A (en) 1983-03-11
EG11025A (en) 1976-11-30
AR202472A1 (es) 1975-06-13
NO740281L (nl) 1975-07-14
IL44033A (en) 1977-10-31
NO145794C (no) 1982-06-09
NL7401174A (nl) 1975-06-17
AU6463674A (en) 1975-07-17
ES422732A2 (es) 1977-07-01
FI62840B (fi) 1982-11-30
JPS5874688A (ja) 1983-05-06
GB1462421A (en) 1977-01-26
DK150856C (da) 1987-11-16
KR780000354B1 (en) 1978-09-16
CH596218A5 (nl) 1978-03-15
DD113008A6 (nl) 1975-05-12

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