ZA744461B - New alkoxyalkyl-1,4-dihydropyridines, their preparation and their medicinal use - Google Patents

New alkoxyalkyl-1,4-dihydropyridines, their preparation and their medicinal use

Info

Publication number
ZA744461B
ZA744461B ZA00744461A ZA744461A ZA744461B ZA 744461 B ZA744461 B ZA 744461B ZA 00744461 A ZA00744461 A ZA 00744461A ZA 744461 A ZA744461 A ZA 744461A ZA 744461 B ZA744461 B ZA 744461B
Authority
ZA
South Africa
Prior art keywords
dihydropyridines
alkoxyalkyl
preparation
new
medicinal use
Prior art date
Application number
ZA00744461A
Other languages
English (en)
Inventor
K Stoepel
E Wehinger
W Vater
F Bossert
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA744461B publication Critical patent/ZA744461B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
ZA00744461A 1973-07-12 1974-07-11 New alkoxyalkyl-1,4-dihydropyridines, their preparation and their medicinal use ZA744461B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732335466 DE2335466A1 (de) 1973-07-12 1973-07-12 Alkoxyalkyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ZA744461B true ZA744461B (en) 1975-07-30

Family

ID=5886689

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00744461A ZA744461B (en) 1973-07-12 1974-07-11 New alkoxyalkyl-1,4-dihydropyridines, their preparation and their medicinal use

Country Status (21)

Country Link
JP (3) JPS6011030B2 (fi)
AT (1) AT337699B (fi)
AU (1) AU477107B2 (fi)
BE (1) BE817540A (fi)
CA (1) CA1025450A (fi)
CH (2) CH614196A5 (fi)
DD (1) DD118631A5 (fi)
DE (1) DE2335466A1 (fi)
DK (1) DK373974A (fi)
ES (5) ES428185A1 (fi)
FI (1) FI212074A (fi)
FR (1) FR2236497B1 (fi)
GB (1) GB1436289A (fi)
HU (1) HU171401B (fi)
IE (1) IE39602B1 (fi)
IL (1) IL45233A (fi)
LU (1) LU70498A1 (fi)
NL (1) NL7409344A (fi)
PL (2) PL91873B1 (fi)
SE (1) SE7409146L (fi)
ZA (1) ZA744461B (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
GB1591089A (en) * 1976-12-17 1981-06-10 Fujisawa Pharmaceutical Co 1,4-dihydropyridine derivatives and process for preparation thereof
JPS53146941U (fi) * 1977-04-26 1978-11-18
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
DE3312283A1 (de) * 1983-04-05 1984-10-18 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3312216A1 (de) * 1983-04-05 1984-10-11 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3432563A1 (de) * 1984-09-05 1986-03-13 Bayer Ag, 5090 Leverkusen Neue pyridylethyl-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimittel
GB8428552D0 (en) * 1984-11-12 1984-12-19 Sandoz Ltd Organic compounds
US4678796A (en) * 1984-11-30 1987-07-07 Warner-Lambert Company 2-alkylidene derivatives of 1,2,3,4-tetrahydropyridine-2,5-pyridine carboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
FI862343A (fi) 1985-06-17 1986-12-18 Warner Lambert Co Foerfarande foer framstaellning av terapeutiskt verkande 1,4-dihydropyridinfoereningar.
US4732898A (en) * 1986-04-29 1988-03-22 Warner-Lambert Company 2-(2-aryl-2-oxoalkylidene) analogs of-3,5-pyridinedicarboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
JPS6378289A (ja) * 1986-09-20 1988-04-08 株式会社富士通ゼネラル 車両の台数検出装置
AT399872B (de) * 1988-03-08 1995-08-25 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
AT399873B (de) * 1988-03-08 1995-08-25 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
GR1002248B (en) * 1988-03-08 1996-04-23 Egyt Gyogyszervegyeszeti Gyar 1,4-dihydropyridine derivatives preparation method
AT400241B (de) * 1988-03-08 1995-11-27 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
FR2672890A1 (fr) * 1991-02-20 1992-08-21 Inst Investigacion Desarrol Derives de 2,6-dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine, leur procede de preparation et leur utilisation comme capteurs de radicaux libres.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern

Also Published As

Publication number Publication date
FR2236497B1 (fi) 1978-07-21
FR2236497A1 (fi) 1975-02-07
CH622507A5 (en) 1981-04-15
DK373974A (fi) 1975-03-03
JPS57131763A (en) 1982-08-14
DE2335466A1 (de) 1975-01-30
ES428185A1 (es) 1976-12-16
CA1025450A (en) 1978-01-31
IL45233A (en) 1978-06-15
JPS6011030B2 (ja) 1985-03-22
BE817540A (fr) 1975-01-13
ES448394A1 (es) 1977-07-16
SE7409146L (sv) 1975-01-13
DD118631A5 (fi) 1976-03-12
GB1436289A (en) 1976-05-19
ES448396A1 (es) 1977-09-16
AU477107B2 (en) 1976-10-14
IE39602B1 (en) 1978-11-22
CH614196A5 (en) 1979-11-15
ATA569674A (de) 1976-11-15
HU171401B (hu) 1978-01-28
JPS5943952B2 (ja) 1984-10-25
PL94266B1 (fi) 1977-07-30
JPS5040578A (fi) 1975-04-14
ES448397A1 (es) 1977-08-01
IE39602L (en) 1975-01-12
IL45233A0 (en) 1974-10-22
JPS5943951B2 (ja) 1984-10-25
JPS57131764A (en) 1982-08-14
FI212074A (fi) 1975-01-13
LU70498A1 (fi) 1975-03-27
PL91873B1 (fi) 1977-03-31
NL7409344A (nl) 1975-01-14
ES448395A1 (es) 1977-09-16
AT337699B (de) 1977-07-11
AU7096974A (en) 1976-01-08

Similar Documents

Publication Publication Date Title
IL48592A (en) 1-substituted-4-benzypiperidine derivatives,their preparation and pharmaceutical composistions comprising them
ZA744461B (en) New alkoxyalkyl-1,4-dihydropyridines, their preparation and their medicinal use
EG12207A (en) New amino-sugar compounds,their production and their medicinal use
IL44710A0 (en) Azolyl-amidines,their preparation and their use as herbicides
HK70276A (en) New 1-substituted pyrazol-5-ones, their production and their medicinal use
IL45609A0 (en) New isoquinoline derivatives,their preparation and pharmaceutical compositions containing them
ZA735974B (en) New 2-amino-1,4-dihydropyridines,their production and their medicinal use
HK55876A (en) New pyrazol-5-ones, their preparation and their pharmaceutical use
IL44222A0 (en) New diphenylpropylamines,their preparation and pharmaceutical compositions containing them
AU6972074A (en) Phthalayine derivatives, preparation and use
IL44895A0 (en) New thiazoloisoquinolines,their preparation and pharmaceutical compositions containing them
IL44849A0 (en) New nitrocarbostyrils,their preparation and pharmaceutical compositions containing them
IL49099A0 (en) New xanthene-9-carboxylates,their preparation and pharmaceutical compositions containing them
ZA74644B (en) New phenylguanidines,their preparation and their medicinal use
ZA741354B (en) New 2-amino-3, 4-dihydropyridines, their production and their medicinal use
GR60560B (en) Penicillines,preparation process and use thereof as medicines
IL44666A0 (en) Dichlorothiazolylureas,their preparation and their use as herbicides
ZA742384B (en) New pyrazol-5-ones, their preparation and their pharmaceutical use
ZA745909B (en) New acylamino-phenyl-acetamidine compounds, their production and their medicinal use
ZA742381B (en) New-1-substituted pyrazol-5-sones, their production and their medicinal use
ZA745608B (en) 3,3-methylene-bis-(4-hydroxy-5-azacoumarin) its preparation and use
IL44000A0 (en) 1-alkylideneaminouracils,their preparation and their use as herbicides
IL45421A0 (en) Thiadiazolylureas,their preparation and their use as herbicides
KE2657A (en) New benzoylphenylisothioureas, their production, and their medicinal use
ZA745657B (en) 7-monochloroacetamido-3-desacetoxycephalosporanic acid derivatives, their preparation and use