ZA744208B - Method for in vitro propagation and maintenance of cells - Google Patents

Method for in vitro propagation and maintenance of cells

Info

Publication number
ZA744208B
ZA744208B ZA00744208A ZA744208A ZA744208B ZA 744208 B ZA744208 B ZA 744208B ZA 00744208 A ZA00744208 A ZA 00744208A ZA 744208 A ZA744208 A ZA 744208A ZA 744208 B ZA744208 B ZA 744208B
Authority
ZA
South Africa
Prior art keywords
maintenance
cells
vitro propagation
vitro
propagation
Prior art date
Application number
ZA00744208A
Other languages
English (en)
Inventor
J Delente
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of ZA744208B publication Critical patent/ZA744208B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/0231—Chemically defined matrices, e.g. alginate gels, for immobilising, holding or storing cells, tissue or organs for preservation purposes; Chemically altering or fixing cells, tissue or organs, e.g. by cross-linking, for preservation purposes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/10—Hollow fibers or tubes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA00744208A 1973-07-02 1974-07-01 Method for in vitro propagation and maintenance of cells ZA744208B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/376,038 US3997396A (en) 1973-07-02 1973-07-02 Method for the in vitro propagation and maintenance of cells

Publications (1)

Publication Number Publication Date
ZA744208B true ZA744208B (en) 1975-06-25

Family

ID=23483444

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00744208A ZA744208B (en) 1973-07-02 1974-07-01 Method for in vitro propagation and maintenance of cells

Country Status (12)

Country Link
US (1) US3997396A (fr)
JP (1) JPS554395B2 (fr)
BE (1) BE817119A (fr)
CA (1) CA1107211A (fr)
CH (1) CH593339A5 (fr)
DE (1) DE2431450C2 (fr)
FR (1) FR2236004B1 (fr)
GB (1) GB1448176A (fr)
IL (1) IL45168A (fr)
IT (1) IT1015692B (fr)
NL (1) NL179923C (fr)
ZA (1) ZA744208B (fr)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201845A (en) * 1976-04-12 1980-05-06 Monsanto Company Cell culture reactor
US4087327A (en) * 1976-04-12 1978-05-02 Monsanto Company Mammalion cell culture process
JPS5730472Y2 (fr) * 1976-09-22 1982-07-03
US4229541A (en) * 1978-10-06 1980-10-21 Baxter Travenol Laboratories, Inc. In vitro cultivation of horseshoe crab amebocytes
JPS5642584A (en) * 1979-09-18 1981-04-20 Asahi Chem Ind Co Ltd Cell cultivation method
DE2940446C2 (de) * 1979-10-05 1982-07-08 B. Braun Melsungen Ag, 3508 Melsungen Züchtung von tierischen Zellen in Suspensions- und Monolayerkulturen in Fermentationsgefäßen
US4301249A (en) * 1980-07-23 1981-11-17 Merck & Co., Inc. High titer production of hepatitis A virus
CH651587A5 (de) * 1980-11-18 1985-09-30 Chemap Ag Verfahren und vorrichtung zur submersen zuechtung von zellkulturen.
JPS5876086A (ja) * 1981-10-28 1983-05-09 Ajinomoto Co Inc 浮遊性動物細胞の培養法
US4537860A (en) * 1982-12-08 1985-08-27 Monsanto Company Static cell culture maintenance system
US4546083A (en) * 1983-04-22 1985-10-08 Stolle Research & Development Corporation Method and device for cell culture growth
US4764471A (en) * 1984-01-04 1988-08-16 Nabisco Brands, Inc. Continuous bioreactor and process
JPH0646956B2 (ja) * 1984-01-27 1994-06-22 フ−パ−・トレ−デイング・カンパニ−・エヌ・ベ− 血清不含およびミトゲン不含インタ−ル−キン−２の試験管内の効率生産法
JPH06165690A (ja) * 1984-01-27 1994-06-14 Hooper Trading Co Nv 血清不含およびミトゲン不含インタールーキン−２の試験管内での効率生産方法
US5180676A (en) * 1984-06-14 1993-01-19 Teijin Limited Method of cultivating animal or plant cells
SE439814B (sv) * 1984-07-18 1985-07-01 Karl Gustav Hesselmar Fasthallningsanordning, for fastsettning i halrum, vilken expanderas till fasthallningsleget genom miljopaverkan
CA1275273C (fr) * 1984-10-09 1990-10-16 Micheal L. Gruenberg Dispositif de culture de cellules a fibres creuses et methode de fonctionnement
US4804628A (en) * 1984-10-09 1989-02-14 Endotronics, Inc. Hollow fiber cell culture device and method of operation
WO1986002379A1 (fr) * 1984-10-09 1986-04-24 Endotronics, Inc. Dispositif de culture a fibres creuses pour ameliorer la perfusion de substances nutritives et la concentration des produits, et procede de fonctionnement
US4748124A (en) * 1984-10-30 1988-05-31 E. I. Du Pont De Nemours And Company Compartmentalized cell-culture device and method
GB8428085D0 (en) * 1984-11-07 1984-12-12 Manchester Inst Science Tech Immobilisation of biological material
GB8508976D0 (en) * 1985-04-04 1985-05-09 Davies G A Reactor unit
FR2580514B1 (fr) * 1985-04-17 1989-08-18 Lyonnaise Eaux Ensemble composite de membranes de filtration et son utilisation dans un bioreacteur
US4647539A (en) * 1985-05-24 1987-03-03 Endotronics, Inc. Method and apparatus for growing cells in vitro
US4720462A (en) * 1985-11-05 1988-01-19 Robert Rosenson Culture system for the culture of solid tissue masses and method of using the same
US4661455A (en) * 1986-01-16 1987-04-28 Dorr-Oliver Incorporated Membrane cell culturing device
US4920055A (en) * 1986-02-04 1990-04-24 American Biogenetics Corporation Conversion of alcohols to aldehydes and hydrogen peroxide by substrate and product tolerant methanol oxidases
JPS647278Y2 (fr) * 1986-03-10 1989-02-27
WO1987006120A1 (fr) * 1986-04-18 1987-10-22 Marrow-Tech Incorporated Procede de reproduction de la moelle osseuse
US5510254A (en) * 1986-04-18 1996-04-23 Advanced Tissue Sciences, Inc. Three dimensional cell and tissue culture system
US5032508A (en) * 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5863531A (en) * 1986-04-18 1999-01-26 Advanced Tissue Sciences, Inc. In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework
US5266480A (en) * 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US5160490A (en) * 1986-04-18 1992-11-03 Marrow-Tech Incorporated Three-dimensional cell and tissue culture apparatus
US4963489A (en) * 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
DE3711699A1 (de) * 1987-04-07 1988-11-10 Fraunhofer Ges Forschung Medium zur kultivierung und proliferation von epithelialen zelltypen
US4975377A (en) * 1987-05-14 1990-12-04 Key Marc E Cell growth chambers and method of use thereof
US4994388A (en) * 1988-04-15 1991-02-19 Solohill Engineering, Inc. Collagen-coated polystyrene microcarrier beads
US5081035A (en) * 1988-04-18 1992-01-14 The University Of Michigan Bioreactor system
US4999298A (en) * 1988-04-27 1991-03-12 W. R. Grace & Co.-Conn. Hollow fiber bioreactor culture system and method
WO1989011529A1 (fr) * 1988-05-23 1989-11-30 The Regents Of The University Of Minnesota Bioreacteur
US5605835A (en) * 1988-05-23 1997-02-25 Regents Of The University Of Minnesota Bioreactor device with application as a bioartificial liver
US5079168A (en) * 1988-08-10 1992-01-07 Endotronics, Inc. Cell culture apparatus
FR2639222B1 (fr) * 1988-11-18 1995-02-24 Cartier Claude Julien Appareil pour traiter les desequilibres vasculaires, metaboliques et fonctionnels et les oedemes d'un membre par variations de pression d'un fluide de densite elevee autour de ce membre
US5162225A (en) * 1989-03-17 1992-11-10 The Dow Chemical Company Growth of cells in hollow fibers in an agitated vessel
US4897359A (en) * 1989-03-27 1990-01-30 Bio-Response, Inc. Apparatus for oxygenating culture medium
US5190879A (en) * 1990-05-08 1993-03-02 Bowolfe, Inc. Controlled environment animal isolation systems
US5112760A (en) * 1990-06-05 1992-05-12 Centocor, Incorporated Mass transfer membrane for oxygenation of animal cell reactors
CA2098510A1 (fr) * 1990-12-13 1992-06-14 Kenneth W. Culver Production soutenue et continue de fortes concentrations de vecteurs viraux recombinants et transduction de cellules cibles utilisables a des fins de therapie genique
WO1995027040A1 (fr) * 1994-04-01 1995-10-12 Unisyn Technologies, Inc. Additifs pour un milieu de culture destine a des bioreacteurs a fibres creuses
DE19528871C2 (de) * 1994-08-24 1997-08-14 Forschungszentrum Juelich Gmbh Begasungs-Rohrmodul mit selektiv gasdurchlässiger Schlauchmembranen und damit versehene Reaktoren für Zellkulturtechnik sowie Wirbelschicht-Reaktoren für Zellkultivierung
US6133019A (en) * 1995-03-28 2000-10-17 Kinetic Biosystems, Inc. Centrifugal fermentation process
US5622819A (en) * 1995-03-28 1997-04-22 Kinetic Biosystems, Inc. Centrifugal fermentation process
US6916652B2 (en) * 1995-03-28 2005-07-12 Kinetic Biosystems, Inc. Biocatalyst chamber encapsulation system for bioremediation and fermentation
US6214617B1 (en) 1995-03-28 2001-04-10 Kinetic Biosystems, Inc. Centrifugal fermentation process
US20050266548A1 (en) * 1995-03-28 2005-12-01 Kbi Biopharma, Inc. Biocatalyst chamber encapsulation system for bioremediation and fermentation with improved rotor
US6660509B1 (en) 1995-03-28 2003-12-09 Kinetic Biosystems, Inc. Methods and devices for remediation and fermentation
US5702949A (en) * 1995-06-22 1997-12-30 University Of Utah Research Foundation Culture method for multilayer growth of anchorage-dependent cells
US20020182730A1 (en) * 1995-07-26 2002-12-05 Micheal L. Gruenberg Autologous immune cell therapy: cell compositions, methods and applications to treatment of human disease
US5827729A (en) * 1996-04-23 1998-10-27 Advanced Tissue Sciences Diffusion gradient bioreactor and extracorporeal liver device using a three-dimensional liver tissue
US6893877B2 (en) 1998-01-12 2005-05-17 Massachusetts Institute Of Technology Methods for screening substances in a microwell array
US6235196B1 (en) 1998-04-23 2001-05-22 Alliedsignal Inc. Biological wastewater treatment system
US6207448B1 (en) 1998-09-02 2001-03-27 Cedars-Sinai Medical Center Bioreactor and related method
US7560274B1 (en) * 1999-05-28 2009-07-14 Cellon S.A. Culture chamber
ATE373079T1 (de) * 1999-06-21 2007-09-15 Gen Hospital Corp Zellkultursysteme und verfahren für einrichtungen zur organunterstützung
AU2001236601A1 (en) 2000-01-31 2001-08-07 Robert A. Cuneo Methods and devices for remediation and fermentation
US6242248B1 (en) 2000-02-08 2001-06-05 Cedars-Sinai Medical Center Bioreactor and related method
WO2001058501A1 (fr) * 2000-02-09 2001-08-16 Minntech Corporation Appareil et procede de suppression de dioxyde de carbone dans un systeme bioreacteur
US20020151040A1 (en) 2000-02-18 2002-10-17 Matthew O' Keefe Apparatus and methods for parallel processing of microvolume liquid reactions
US7332271B2 (en) 2000-02-18 2008-02-19 Board Of Trustees Of The Leland Stanford Junior University Apparatus and methods for parallel processing of micro-volume liquid reactions
US20100261159A1 (en) 2000-10-10 2010-10-14 Robert Hess Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof
CA2425476C (fr) * 2000-10-10 2011-02-01 Biotrove, Inc. Dispositifs d'essai biologique, de synthese et de stockage, et procedes de fabrication, d'utilisation et de manipulation de tels dispositifs
US6635441B2 (en) * 2001-02-08 2003-10-21 Irm, Llc Multi-sample fermentor and method of using same
FR2821947B1 (fr) * 2001-03-12 2003-05-16 Canon Kk Procede et dispositif de validation de parametres definissant une image
US20030134341A1 (en) * 2001-09-19 2003-07-17 Medcell Biologics, Llc. Th1 cell adoptive immunotherapy
US20030134415A1 (en) * 2001-09-19 2003-07-17 Gruenberg Micheal L. Th1 cell adoptive immunotherapy
JP4355212B2 (ja) * 2001-12-21 2009-10-28 オーガノジェネシス インコーポレーテッド 細胞培養及び臓器補助用の可変容量チャンバ
DE10203644A1 (de) * 2002-01-30 2003-08-07 Fraunhofer Ges Forschung Kryokonservierung an textilen Geweben
US20030175272A1 (en) * 2002-03-07 2003-09-18 Medcell Biologics, Inc. Re-activated T-cells for adoptive immunotherapy
DE10393303D2 (de) * 2002-05-31 2005-06-23 Probiogen Ag Kultursysteme zur sterilen kontinuierlichen Kultivierung von Zellen
US8277753B2 (en) 2002-08-23 2012-10-02 Life Technologies Corporation Microfluidic transfer pin
AU2003302264A1 (en) 2002-12-20 2004-09-09 Biotrove, Inc. Assay apparatus and method using microfluidic arrays
AU2005222618A1 (en) 2004-03-12 2005-09-29 Biotrove, Inc. Nanoliter array loading
US7531351B2 (en) * 2004-06-14 2009-05-12 Probiogen Ag Liquid-gas-phase exposure reactor for cell culturing
US20060105453A1 (en) 2004-09-09 2006-05-18 Brenan Colin J Coating process for microfluidic sample arrays
US7754241B1 (en) 2004-11-12 2010-07-13 Clemson University Research Foundation Macromonomer for preparation of a degradable hydrogel
US9427496B2 (en) 2005-02-18 2016-08-30 Drexel University Method for creating an internal transport system within tissue scaffolds using computer-aided tissue engineering
ZA200602094B (en) * 2006-01-16 2007-11-28 Reliance Life Sciences Pvt Ltd Device for culturing and transporting cells
US8293531B1 (en) 2007-08-31 2012-10-23 Clemson University Research Foundation Three-dimensional ex vivo system
DK2421951T3 (da) * 2009-04-23 2013-08-26 Hemarina Bioreaktor der anvender oxygen-bærende molekyler
US8778669B2 (en) * 2009-07-22 2014-07-15 Corning Incorporated Multilayer tissue culture vessel
WO2012048298A2 (fr) 2010-10-08 2012-04-12 Caridianbct, Inc. Procédés et systèmes de culture et de récolte de cellules dans un système de bioréacteur à fibres creuses avec conditions de régulation
SG10201604543PA (en) 2011-06-06 2016-07-28 ReGenesys BVBA Expansion of stem cells in hollow fiber bioreactors
US20140017263A1 (en) 2012-06-28 2014-01-16 Clemson University Delivery Agents for Targeted Treatment of Elastin Degradation
US9005550B2 (en) 2012-10-29 2015-04-14 Corning Incorporated Multi-layered cell culture vessel with manifold grips
US9795573B2 (en) 2013-09-24 2017-10-24 Clemson University Multi-step connective tissue stabilization method and stabilized tissue formed thereby
CN105793411B (zh) 2013-11-16 2018-04-17 泰尔茂比司特公司 生物反应器中的细胞扩增
US20170080426A1 (en) * 2014-05-14 2017-03-23 University Of Limerick Device and method for testing compounds on living cells
DE102020102420A1 (de) 2020-01-31 2021-08-05 Rwth Aachen Gas-Flüssig-Reaktor zur blasenfreien Begasung einer Prozessflüssigkeit

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3027305A (en) * 1959-01-16 1962-03-27 Robert R Freeman Apparatus for the cultivation of microorganisms
DE2128744C3 (de) * 1971-06-09 1979-03-29 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen Verfahren zur Massenkultivation von Zellen und Geweben
US3821087A (en) * 1972-05-18 1974-06-28 Dedrick R Cell culture on semi-permeable tubular membranes

Also Published As

Publication number Publication date
US3997396A (en) 1976-12-14
IL45168A (en) 1976-10-31
FR2236004A1 (fr) 1975-01-31
NL179923C (nl) 1986-12-01
BE817119A (fr) 1975-01-02
JPS554395B2 (fr) 1980-01-30
NL7408821A (nl) 1975-01-06
NL179923B (nl) 1986-07-01
IT1015692B (it) 1977-05-20
CH593339A5 (fr) 1977-11-30
FR2236004B1 (fr) 1978-11-24
GB1448176A (en) 1976-09-02
IL45168A0 (en) 1974-10-22
DE2431450A1 (de) 1975-01-23
CA1107211A (fr) 1981-08-18
AU7066174A (en) 1976-01-08
JPS5036684A (fr) 1975-04-05
DE2431450C2 (de) 1986-10-16

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