ZA742575B - Prostaglandin analogs - Google Patents

Prostaglandin analogs

Info

Publication number
ZA742575B
ZA742575B ZA00742575A ZA742575A ZA742575B ZA 742575 B ZA742575 B ZA 742575B ZA 00742575 A ZA00742575 A ZA 00742575A ZA 742575 A ZA742575 A ZA 742575A ZA 742575 B ZA742575 B ZA 742575B
Authority
ZA
South Africa
Prior art keywords
prostaglandin analogs
prostaglandin
analogs
Prior art date
Application number
ZA00742575A
Other languages
English (en)
Inventor
N Nelson
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of ZA742575B publication Critical patent/ZA742575B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA00742575A 1973-05-21 1974-04-23 Prostaglandin analogs ZA742575B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US361990A US3864387A (en) 1973-05-21 1973-05-21 5-Oxa phenyl-and phenoxy-substituted prostaglandin F{HD 1{301 {0 {B analogs

Publications (1)

Publication Number Publication Date
ZA742575B true ZA742575B (en) 1975-04-30

Family

ID=23424247

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00742575A ZA742575B (en) 1973-05-21 1974-04-23 Prostaglandin analogs

Country Status (15)

Country Link
US (1) US3864387A (de)
JP (1) JPS5738577B2 (de)
AU (1) AU476578B2 (de)
BE (1) BE815354A (de)
CH (1) CH610299A5 (de)
DE (1) DE2423155A1 (de)
DK (1) DK142079B (de)
GB (1) GB1448413A (de)
HU (1) HU173540B (de)
IL (2) IL44621A (de)
NL (1) NL7406557A (de)
PL (1) PL99931B1 (de)
SE (1) SE425311B (de)
SU (1) SU662008A3 (de)
ZA (1) ZA742575B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3933899A (en) * 1972-10-30 1976-01-20 The Upjohn Company PGE2 -oxa-phenylene compounds
US4031081A (en) * 1973-07-20 1977-06-21 The Upjohn Company Bicyclic intermediates for preparing 16-alkylated prostaglandin analogs
US3993686A (en) * 1973-11-12 1976-11-23 The Upjohn Company Phenyl substituted prostaglandins-C-type analogs
DE2365101A1 (de) * 1973-12-21 1975-07-10 Schering Ag Neue prostansaeurederivate und verfahren zu ihrer herstellung
US3996266A (en) * 1974-04-11 1976-12-07 The Upjohn Company 4-Oxa phenyl-substituted PGE compounds
US3980694A (en) * 1974-04-11 1976-09-14 The Upjohn Company 4-Oxa phenyl-substituted PGA compounds
US3996267A (en) * 1974-04-11 1976-12-07 The Upjohn Company 3-Oxo phenyl-substituted PGF compounds
US3983158A (en) * 1974-04-11 1976-09-28 The Upjohn Company 3-Oxa phenyl-substituted PGA compounds
US3983157A (en) * 1974-04-11 1976-09-28 The Upjohn Company 4-Oxa phenyl-substituted PGF compounds
US3974146A (en) * 1975-04-09 1976-08-10 The Upjohn Company Cyanolpoxy intermediates for prostaglandins and process for preparing same
USRE30053E (en) * 1975-06-23 1979-07-24 The Upjohn Company PG-type, 1,9-lactones
ES449162A1 (es) 1975-06-23 1977-12-16 Syntex Inc Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico.
US4638100A (en) * 1976-01-08 1987-01-20 The Upjohn Company Aromatic or inter-oxa 2-decarboxy-2-hydroxymethyl-PGFα compounds
HU174554B (hu) * 1976-02-23 1980-02-28 Chinoin Gyogyszer Es Vegyeszet Novyj sposob poluchenija biciklicheskikh ehnonnykh soedinenij
US4144251A (en) * 1976-03-02 1979-03-13 American Home Products Corporation 5-Unsaturated prostanoic acid derivatives
US4052552A (en) * 1976-08-20 1977-10-04 The Upjohn Company Thromboxane b analogs
US4054737A (en) * 1976-08-20 1977-10-18 The Upjohn Company Thromboxane B analogs
US4171948A (en) * 1977-12-27 1979-10-23 General Kinematics Corporation Slag handling apparatus
US4289785A (en) * 1980-08-06 1981-09-15 The Upjohn Company Method and compositions involving prostaglandins
US4289761A (en) * 1980-08-06 1981-09-15 The Upjohn Company Combination of 5-oxa-17-phenyl-PGF1 α's estrogenic compounds for menses induction
US4513103A (en) * 1983-10-21 1985-04-23 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane ethers useful in the treatment of thrombolytic disease
GB0112699D0 (en) 2001-05-24 2001-07-18 Resolution Chemicals Ltd Process for the preparation of prostglandins and analogues thereof
WO2004110972A1 (ja) * 2003-06-10 2004-12-23 Ono Pharmaceutical Co., Ltd. (2r)−2−プロピルオクタン酸の製造方法、その中間体
EP2454227B1 (de) 2009-07-13 2020-08-19 Patheon API Services Inc. Prostanoid-synthese
KR102311896B1 (ko) 2013-09-30 2021-10-14 패턴 에이피아이 서비시즈 인코포레이티드 복분해를 사용하는 프로스타글란딘 및 프로스타글란딘 중간체의 합성 경로

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA972356A (en) * 1970-12-31 1975-08-05 Gordon L. Bundy Prostaglandins
US4304907A (en) * 1972-05-10 1981-12-08 The Upjohn Company Bicyclo lactone intermediates for prostaglandin analogs

Also Published As

Publication number Publication date
BE815354A (fr) 1974-11-21
JPS5018442A (de) 1975-02-26
US3864387A (en) 1975-02-04
AU476578B2 (en) 1976-09-30
AU6835374A (en) 1975-10-30
HU173540B (hu) 1979-06-28
NL7406557A (de) 1974-11-25
DK142079B (da) 1980-08-25
SE425311B (sv) 1982-09-20
IL44621A0 (en) 1974-06-30
IL44621A (en) 1979-07-25
IL44620A (en) 1979-07-25
CH610299A5 (de) 1979-04-12
GB1448413A (en) 1976-09-08
JPS5738577B2 (de) 1982-08-16
PL99931B1 (pl) 1978-08-31
DE2423155A1 (de) 1974-12-12
SU662008A3 (ru) 1979-05-05
DK142079C (de) 1981-01-26

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