IL44621A - 5-oxa- -aryl-prostaglandin f 1 compounds - Google Patents

5-oxa- -aryl-prostaglandin f 1 compounds

Info

Publication number
IL44621A
IL44621A IL44621A IL4462174A IL44621A IL 44621 A IL44621 A IL 44621A IL 44621 A IL44621 A IL 44621A IL 4462174 A IL4462174 A IL 4462174A IL 44621 A IL44621 A IL 44621A
Authority
IL
Israel
Prior art keywords
prostaglandin
oxa
aryl
compounds
Prior art date
Application number
IL44621A
Other languages
English (en)
Other versions
IL44621A0 (en
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of IL44621A0 publication Critical patent/IL44621A0/xx
Publication of IL44621A publication Critical patent/IL44621A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL44621A 1973-05-21 1974-04-12 5-oxa- -aryl-prostaglandin f 1 compounds IL44621A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US361990A US3864387A (en) 1973-05-21 1973-05-21 5-Oxa phenyl-and phenoxy-substituted prostaglandin F{HD 1{301 {0 {B analogs

Publications (2)

Publication Number Publication Date
IL44621A0 IL44621A0 (en) 1974-06-30
IL44621A true IL44621A (en) 1979-07-25

Family

ID=23424247

Family Applications (2)

Application Number Title Priority Date Filing Date
IL44621A IL44621A (en) 1973-05-21 1974-04-12 5-oxa- -aryl-prostaglandin f 1 compounds
IL44620A IL44620A (en) 1973-05-21 1974-04-12 5-oxa- -aryl-prostaglandin f1 compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL44620A IL44620A (en) 1973-05-21 1974-04-12 5-oxa- -aryl-prostaglandin f1 compounds

Country Status (15)

Country Link
US (1) US3864387A (xx)
JP (1) JPS5738577B2 (xx)
AU (1) AU476578B2 (xx)
BE (1) BE815354A (xx)
CH (1) CH610299A5 (xx)
DE (1) DE2423155A1 (xx)
DK (1) DK142079B (xx)
GB (1) GB1448413A (xx)
HU (1) HU173540B (xx)
IL (2) IL44621A (xx)
NL (1) NL7406557A (xx)
PL (1) PL99931B1 (xx)
SE (1) SE425311B (xx)
SU (1) SU662008A3 (xx)
ZA (1) ZA742575B (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3933899A (en) * 1972-10-30 1976-01-20 The Upjohn Company PGE2 -oxa-phenylene compounds
US4031081A (en) * 1973-07-20 1977-06-21 The Upjohn Company Bicyclic intermediates for preparing 16-alkylated prostaglandin analogs
US3993686A (en) * 1973-11-12 1976-11-23 The Upjohn Company Phenyl substituted prostaglandins-C-type analogs
DE2365101A1 (de) * 1973-12-21 1975-07-10 Schering Ag Neue prostansaeurederivate und verfahren zu ihrer herstellung
US3983158A (en) * 1974-04-11 1976-09-28 The Upjohn Company 3-Oxa phenyl-substituted PGA compounds
US3980694A (en) * 1974-04-11 1976-09-14 The Upjohn Company 4-Oxa phenyl-substituted PGA compounds
US3996266A (en) * 1974-04-11 1976-12-07 The Upjohn Company 4-Oxa phenyl-substituted PGE compounds
US3983157A (en) * 1974-04-11 1976-09-28 The Upjohn Company 4-Oxa phenyl-substituted PGF compounds
US3996267A (en) * 1974-04-11 1976-12-07 The Upjohn Company 3-Oxo phenyl-substituted PGF compounds
US3974146A (en) * 1975-04-09 1976-08-10 The Upjohn Company Cyanolpoxy intermediates for prostaglandins and process for preparing same
USRE30053E (en) * 1975-06-23 1979-07-24 The Upjohn Company PG-type, 1,9-lactones
ES449162A1 (es) 1975-06-23 1977-12-16 Syntex Inc Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico.
US4638100A (en) * 1976-01-08 1987-01-20 The Upjohn Company Aromatic or inter-oxa 2-decarboxy-2-hydroxymethyl-PGFα compounds
HU174554B (hu) * 1976-02-23 1980-02-28 Chinoin Gyogyszer Es Vegyeszet Novyj sposob poluchenija biciklicheskikh ehnonnykh soedinenij
US4144251A (en) * 1976-03-02 1979-03-13 American Home Products Corporation 5-Unsaturated prostanoic acid derivatives
US4054737A (en) * 1976-08-20 1977-10-18 The Upjohn Company Thromboxane B analogs
US4052552A (en) * 1976-08-20 1977-10-04 The Upjohn Company Thromboxane b analogs
US4171948A (en) * 1977-12-27 1979-10-23 General Kinematics Corporation Slag handling apparatus
US4289761A (en) * 1980-08-06 1981-09-15 The Upjohn Company Combination of 5-oxa-17-phenyl-PGF1 α's estrogenic compounds for menses induction
US4289785A (en) * 1980-08-06 1981-09-15 The Upjohn Company Method and compositions involving prostaglandins
US4513103A (en) * 1983-10-21 1985-04-23 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane ethers useful in the treatment of thrombolytic disease
GB0112699D0 (en) 2001-05-24 2001-07-18 Resolution Chemicals Ltd Process for the preparation of prostglandins and analogues thereof
JP4742868B2 (ja) * 2003-06-10 2011-08-10 小野薬品工業株式会社 （２ｒ）−２−プロピルオクタン酸の製造方法、その中間体
ES2824842T3 (es) 2009-07-13 2021-05-13 Patheon Api Services Inc Síntesis de prostanoides
KR102311896B1 (ko) 2013-09-30 2021-10-14 패턴 에이피아이 서비시즈 인코포레이티드 복분해를 사용하는 프로스타글란딘 및 프로스타글란딘 중간체의 합성 경로

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA972356A (en) * 1970-12-31 1975-08-05 Gordon L. Bundy Prostaglandins
US4304907A (en) * 1972-05-10 1981-12-08 The Upjohn Company Bicyclo lactone intermediates for prostaglandin analogs

Also Published As

Publication number Publication date
IL44621A0 (en) 1974-06-30
PL99931B1 (pl) 1978-08-31
ZA742575B (en) 1975-04-30
GB1448413A (en) 1976-09-08
CH610299A5 (xx) 1979-04-12
DK142079B (da) 1980-08-25
NL7406557A (xx) 1974-11-25
JPS5738577B2 (xx) 1982-08-16
SE425311B (sv) 1982-09-20
SU662008A3 (ru) 1979-05-05
IL44620A (en) 1979-07-25
DK142079C (xx) 1981-01-26
BE815354A (fr) 1974-11-21
AU6835374A (en) 1975-10-30
JPS5018442A (xx) 1975-02-26
US3864387A (en) 1975-02-04
AU476578B2 (en) 1976-09-30
DE2423155A1 (de) 1974-12-12
HU173540B (hu) 1979-06-28

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