CA972356A - Prostaglandins - Google Patents

Prostaglandins

Info

Publication number
CA972356A
CA972356A CA129,135A CA129135A CA972356A CA 972356 A CA972356 A CA 972356A CA 129135 A CA129135 A CA 129135A CA 972356 A CA972356 A CA 972356A
Authority
CA
Canada
Prior art keywords
prostaglandins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA129,135A
Inventor
Gordon L. Bundy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Priority to CA208,119A priority Critical patent/CA972357A/en
Priority to CA210,904A priority patent/CA972360A/en
Priority to CA210,902A priority patent/CA972358A/en
Priority to CA210,903A priority patent/CA972359A/en
Priority to CA213,447A priority patent/CA972361A/en
Application granted granted Critical
Publication of CA972356A publication Critical patent/CA972356A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • C07C35/27—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system containing six carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA129,135A 1970-12-31 1971-12-02 Prostaglandins Expired CA972356A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA208,119A CA972357A (en) 1970-12-31 1974-08-29 Prostaglandins
CA210,904A CA972360A (en) 1970-12-31 1974-10-07 Prostaglandins
CA210,902A CA972358A (en) 1970-12-31 1974-10-07 Prostaglandins
CA210,903A CA972359A (en) 1970-12-31 1974-10-07 Prostaglandins
CA213,447A CA972361A (en) 1970-12-31 1974-11-12 Prostaglandins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10333870A 1970-12-31 1970-12-31

Publications (1)

Publication Number Publication Date
CA972356A true CA972356A (en) 1975-08-05

Family

ID=22294645

Family Applications (1)

Application Number Title Priority Date Filing Date
CA129,135A Expired CA972356A (en) 1970-12-31 1971-12-02 Prostaglandins

Country Status (10)

Country Link
AU (1) AU460611B2 (en)
BE (1) BE777612A (en)
CA (1) CA972356A (en)
CH (1) CH605726A5 (en)
DE (1) DE2165184A1 (en)
FR (1) FR2120163B1 (en)
GB (1) GB1331826A (en)
NL (1) NL7118204A (en)
SE (2) SE397087B (en)
ZA (1) ZA718157B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3864387A (en) * 1973-05-21 1975-02-04 Upjohn Co 5-Oxa phenyl-and phenoxy-substituted prostaglandin F{HD 1{301 {0 {B analogs
US3983163A (en) * 1973-05-21 1976-09-28 The Upjohn Company 5-Oxa phenyl- and phenoxy-substituted prostaglandin β, analogs
US3966795A (en) * 1973-05-21 1976-06-29 The Upjohn Company 5-Oxa-11-deoxyphenyl- and phenoxy-substituted prostaglandin F1.sub.α analogs
US3968144A (en) * 1973-05-21 1976-07-06 The Upjohn Company 5-Oxa-11-deoxy phenyl- and phenoxy-substituted prostalandin E1 analogs
US3983157A (en) * 1974-04-11 1976-09-28 The Upjohn Company 4-Oxa phenyl-substituted PGF compounds
US3983158A (en) * 1974-04-11 1976-09-28 The Upjohn Company 3-Oxa phenyl-substituted PGA compounds
US3980694A (en) * 1974-04-11 1976-09-14 The Upjohn Company 4-Oxa phenyl-substituted PGA compounds
CN110790737B (en) * 2019-11-07 2022-07-22 河南中烟工业有限责任公司 Preparation method of 2, 3-dihydro-3, 5-dihydroxy-6-ethyl-4H-pyran-4-one

Also Published As

Publication number Publication date
AU3667871A (en) 1973-06-14
FR2120163A1 (en) 1972-08-11
CH605726A5 (en) 1978-10-13
SE397087B (en) 1977-10-17
FR2120163B1 (en) 1975-10-10
NL7118204A (en) 1972-07-04
ZA718157B (en) 1972-09-27
DE2165184A1 (en) 1972-07-13
GB1331826A (en) 1973-09-26
SE7501733L (en) 1975-02-17
BE777612A (en) 1972-06-30
AU460611B2 (en) 1975-05-01

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