ZA718157B - Prostglandin analogs - Google Patents

Prostglandin analogs

Info

Publication number
ZA718157B
ZA718157B ZA718157A ZA718157A ZA718157B ZA 718157 B ZA718157 B ZA 718157B ZA 718157 A ZA718157 A ZA 718157A ZA 718157 A ZA718157 A ZA 718157A ZA 718157 B ZA718157 B ZA 718157B
Authority
ZA
South Africa
Prior art keywords
prostglandin
analogs
prostglandin analogs
Prior art date
Application number
ZA718157A
Inventor
G Bundy
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of ZA718157B publication Critical patent/ZA718157B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • C07C35/27Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system containing six carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA718157A 1970-12-31 1971-12-06 Prostglandin analogs ZA718157B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10333870A 1970-12-31 1970-12-31

Publications (1)

Publication Number Publication Date
ZA718157B true ZA718157B (en) 1972-09-27

Family

ID=22294645

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA718157A ZA718157B (en) 1970-12-31 1971-12-06 Prostglandin analogs

Country Status (10)

Country Link
AU (1) AU460611B2 (en)
BE (1) BE777612A (en)
CA (1) CA972356A (en)
CH (1) CH605726A5 (en)
DE (1) DE2165184A1 (en)
FR (1) FR2120163B1 (en)
GB (1) GB1331826A (en)
NL (1) NL7118204A (en)
SE (2) SE397087B (en)
ZA (1) ZA718157B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966795A (en) * 1973-05-21 1976-06-29 The Upjohn Company 5-Oxa-11-deoxyphenyl- and phenoxy-substituted prostaglandin F1.sub.α analogs
US3968144A (en) * 1973-05-21 1976-07-06 The Upjohn Company 5-Oxa-11-deoxy phenyl- and phenoxy-substituted prostalandin E1 analogs
US3864387A (en) * 1973-05-21 1975-02-04 Upjohn Co 5-Oxa phenyl-and phenoxy-substituted prostaglandin F{HD 1{301 {0 {B analogs
US3983163A (en) * 1973-05-21 1976-09-28 The Upjohn Company 5-Oxa phenyl- and phenoxy-substituted prostaglandin β, analogs
US3980694A (en) * 1974-04-11 1976-09-14 The Upjohn Company 4-Oxa phenyl-substituted PGA compounds
US3983157A (en) * 1974-04-11 1976-09-28 The Upjohn Company 4-Oxa phenyl-substituted PGF compounds
US3983158A (en) * 1974-04-11 1976-09-28 The Upjohn Company 3-Oxa phenyl-substituted PGA compounds
CN110790737B (en) * 2019-11-07 2022-07-22 河南中烟工业有限责任公司 Preparation method of 2, 3-dihydro-3, 5-dihydroxy-6-ethyl-4H-pyran-4-one

Also Published As

Publication number Publication date
SE7501733L (en) 1975-02-17
FR2120163A1 (en) 1972-08-11
DE2165184A1 (en) 1972-07-13
GB1331826A (en) 1973-09-26
CA972356A (en) 1975-08-05
SE397087B (en) 1977-10-17
FR2120163B1 (en) 1975-10-10
AU3667871A (en) 1973-06-14
AU460611B2 (en) 1975-05-01
NL7118204A (en) 1972-07-04
CH605726A5 (en) 1978-10-13
BE777612A (en) 1972-06-30

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