ZA735236B - 6-(alpha-(amidino-and imidoylaminoalkanoylamino)-aracylamino)penicillanic acids and their preparation - Google Patents

6-(alpha-(amidino-and imidoylaminoalkanoylamino)-aracylamino)penicillanic acids and their preparation

Info

Publication number
ZA735236B
ZA735236B ZA735236A ZA735236A ZA735236B ZA 735236 B ZA735236 B ZA 735236B ZA 735236 A ZA735236 A ZA 735236A ZA 735236 A ZA735236 A ZA 735236A ZA 735236 B ZA735236 B ZA 735236B
Authority
ZA
South Africa
Prior art keywords
imidoylaminoalkanoylamino
aracylamino
amidino
alpha
preparation
Prior art date
Application number
ZA735236A
Other languages
English (en)
Inventor
E Hamanaka
J Stam
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA735236B publication Critical patent/ZA735236B/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/66Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/36Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA735236A 1972-08-02 1973-08-01 6-(alpha-(amidino-and imidoylaminoalkanoylamino)-aracylamino)penicillanic acids and their preparation ZA735236B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27706472A 1972-08-02 1972-08-02

Publications (1)

Publication Number Publication Date
ZA735236B true ZA735236B (en) 1974-07-31

Family

ID=23059254

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA735236A ZA735236B (en) 1972-08-02 1973-08-01 6-(alpha-(amidino-and imidoylaminoalkanoylamino)-aracylamino)penicillanic acids and their preparation

Country Status (30)

Country Link
JP (1) JPS5318039B2 (fi)
AR (1) AR206879A1 (fi)
AT (1) AT327382B (fi)
AU (1) AU472676B2 (fi)
BE (1) BE803094A (fi)
BG (1) BG25798A3 (fi)
CA (1) CA1015355A (fi)
CH (1) CH574447A5 (fi)
CS (1) CS168459B2 (fi)
DD (1) DD106849A5 (fi)
DE (1) DE2338389A1 (fi)
DK (1) DK137047B (fi)
EG (1) EG10896A (fi)
ES (1) ES417461A1 (fi)
FI (1) FI56840C (fi)
FR (1) FR2194415B1 (fi)
GB (1) GB1418656A (fi)
HU (1) HU167653B (fi)
IE (1) IE37961B1 (fi)
IL (1) IL42820A (fi)
LU (1) LU68143A1 (fi)
NL (1) NL7310696A (fi)
NO (1) NO144831C (fi)
PH (1) PH12770A (fi)
PL (1) PL96500B1 (fi)
RO (2) RO63748A (fi)
SE (1) SE415977B (fi)
SU (2) SU576944A3 (fi)
YU (1) YU36966B (fi)
ZA (1) ZA735236B (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024130A (en) * 1975-03-31 1977-05-17 Pfizer Inc. Process for the manufacture of alkali metal salts of 6-[2-phenyl-2-(imidoylaminoalkanoylamino)acetamido]penicillanic acids
US4073780A (en) * 1976-06-03 1978-02-14 Pfizer Inc. 4-Pyridylformimidoylglycyl-D-phenylglycine

Also Published As

Publication number Publication date
BG25798A3 (en) 1978-12-12
AT327382B (de) 1976-01-26
DE2338389A1 (de) 1974-02-28
JPS5318039B2 (fi) 1978-06-13
FI56840B (fi) 1979-12-31
JPS4945089A (fi) 1974-04-27
PL96500B1 (pl) 1977-12-31
CA1015355A (en) 1977-08-09
IL42820A (en) 1977-06-30
CH574447A5 (fi) 1976-04-15
SU576944A3 (ru) 1977-10-15
SU576945A3 (ru) 1977-10-15
YU36966B (en) 1984-08-31
IE37961B1 (en) 1977-11-23
CS168459B2 (fi) 1976-06-29
FR2194415B1 (fi) 1976-12-31
FI56840C (fi) 1980-04-10
PH12770A (en) 1979-08-17
GB1418656A (en) 1975-12-24
ES417461A1 (es) 1976-03-01
NL7310696A (fi) 1974-02-05
ATA680773A (de) 1975-04-15
NO144831B (no) 1981-08-10
DK137047C (fi) 1978-08-07
HU167653B (fi) 1975-11-28
EG10896A (en) 1976-07-31
AU472676B2 (en) 1976-06-03
RO63748A (fr) 1979-01-15
BE803094A (fr) 1974-02-01
IL42820A0 (en) 1973-10-25
DK137047B (da) 1978-01-09
AU5843373A (en) 1975-01-30
NO144831C (no) 1981-11-18
FR2194415A1 (fi) 1974-03-01
DD106849A5 (fi) 1974-07-05
AR206879A1 (es) 1976-08-31
SE415977B (sv) 1980-11-17
YU208673A (en) 1982-02-25
IE37961L (en) 1974-02-02
RO68719A2 (ro) 1980-08-15
LU68143A1 (fi) 1974-02-11

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