ZA202002292B - Methods of treating heart failure with preserved ejection fraction - Google Patents
Methods of treating heart failure with preserved ejection fractionInfo
- Publication number
- ZA202002292B ZA202002292B ZA2020/02292A ZA202002292A ZA202002292B ZA 202002292 B ZA202002292 B ZA 202002292B ZA 2020/02292 A ZA2020/02292 A ZA 2020/02292A ZA 202002292 A ZA202002292 A ZA 202002292A ZA 202002292 B ZA202002292 B ZA 202002292B
- Authority
- ZA
- South Africa
- Prior art keywords
- methods
- heart failure
- ejection fraction
- treating heart
- preserved ejection
- Prior art date
Links
- 208000038003 heart failure with preserved ejection fraction Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762566668P | 2017-10-02 | 2017-10-02 | |
| PCT/IB2018/057648 WO2019069230A1 (en) | 2017-10-02 | 2018-10-02 | METHODS OF TREATING CARDIAC INSUFFICIENCY WITH PRESERVED EJECTION FRACTION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA202002292B true ZA202002292B (en) | 2022-12-21 |
Family
ID=63963334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2020/02292A ZA202002292B (en) | 2017-10-02 | 2020-05-04 | Methods of treating heart failure with preserved ejection fraction |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US11617754B2 (https=) |
| EP (1) | EP3691650A1 (https=) |
| JP (1) | JP2020536121A (https=) |
| KR (1) | KR20200102982A (https=) |
| CN (1) | CN111163782A (https=) |
| BR (1) | BR112020006472A2 (https=) |
| CA (1) | CA3078163A1 (https=) |
| IL (1) | IL273723A (https=) |
| MX (1) | MX2020003243A (https=) |
| TW (1) | TW201924689A (https=) |
| WO (1) | WO2019069230A1 (https=) |
| ZA (1) | ZA202002292B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111163782A (zh) | 2017-10-02 | 2020-05-15 | 普克塞尔公司 | 治疗射血分数保留型心力衰竭的方法 |
| MY203360A (en) | 2018-06-06 | 2024-06-26 | Metavant Sciences Gmbh | Methods of treating subjects having diabetes with chronic kidney disease |
| CA3103324A1 (en) | 2018-06-14 | 2019-12-19 | Poxel | Film-coated tablet comprising a triazine derivative for use in the treatment of diabetes |
| CN115770062B (zh) * | 2021-09-07 | 2025-10-10 | 深圳迈瑞生物医疗电子股份有限公司 | 一种超声波数据的处理方法、成像装置 |
| CN116440075B (zh) * | 2023-06-01 | 2025-05-06 | 苏州中化药品工业有限公司 | 一种干混悬剂及其制备方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2804113B1 (fr) | 2000-01-26 | 2004-06-18 | Lipha | Derives animes de dihydro-1,3,5-triazine et leurs applications en therapeutique |
| FR2853650B1 (fr) | 2003-04-10 | 2006-07-07 | Merck Sante Sas | Procede de dedoublement d'amines utiles pour le traitement de desordres associes au syndrome d'insulino-resistance |
| FR2896157B1 (fr) | 2006-01-13 | 2008-09-12 | Merck Sante Soc Par Actions Si | Combinaison de derives de triazine et d'agents de stimulation de secretion d'insuline. |
| FR2896159B1 (fr) | 2006-01-13 | 2008-09-12 | Merck Sante Soc Par Actions Si | Combinaison de derives de triazine et d'agents sensibilisateurs a l'insuline. |
| FR2896161B1 (fr) | 2006-01-13 | 2008-04-04 | Merck Sante Soc Par Actions Si | Utilisation de derives de triazines pour fabriquer un medicament ayant un effet cicatrisant ou angiogenique. |
| DE102008007314A1 (de) | 2008-02-02 | 2009-08-06 | Merck Patent Gmbh | Verfahren zur Herstellung von 3,6-Dihydro-1,3,5-triazinderivaten |
| KR101618198B1 (ko) | 2008-05-23 | 2016-05-04 | 뽁셀 에스아에스 | 3,6-디히드로-1,3,5-트리아진 유도체의 제조방법 |
| BRPI0916197B1 (pt) | 2008-07-29 | 2018-01-23 | Poxel | Processo para isolar componentes enantioméricos de uma mistura de enantiômeros |
| TW201033182A (en) | 2008-12-12 | 2010-09-16 | Poxel | Tetrahydrotriazine compounds for treating diseases associated with AMPK activity |
| US8592370B2 (en) | 2008-12-12 | 2013-11-26 | Poxel S.A.S. | Combination of insulin with triazine derivatives |
| JP5536869B2 (ja) | 2009-03-26 | 2014-07-02 | ポクセル・エスアーエス | 優先晶出法を利用したジヒドロ−１，３，５トリアジンラセミ体のエナンチオマー分離のための方法 |
| FR2948027A1 (fr) * | 2009-07-17 | 2011-01-21 | Merck Sante Sas | Derives amines de dihydro-1,3,5-triazine pour leur utilisation dans le traitement des maladies associees a une ischemie et/ou une reperfusion |
| WO2011154496A1 (en) * | 2010-06-09 | 2011-12-15 | Poxel | Treatment of type 1 diabetes |
| TWI436768B (zh) * | 2010-06-09 | 2014-05-11 | Poxel | 第２型糖尿病之治療 |
| US8742103B2 (en) | 2010-12-01 | 2014-06-03 | Poxel | Separation of triazine derivatives enantiomers using tartaric acid |
| US9211263B2 (en) | 2012-01-06 | 2015-12-15 | Elcelyx Therapeutics, Inc. | Compositions and methods of treating metabolic disorders |
| US20160151461A1 (en) * | 2013-03-14 | 2016-06-02 | The Trustees Of The University Of Pennsylvania | Cardio-Metabolic and Vascular Effects of GLP-1 Metabolites |
| CA2812519A1 (en) | 2013-04-05 | 2014-10-05 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
| EP3110449B1 (en) * | 2014-02-28 | 2023-06-28 | Boehringer Ingelheim International GmbH | Medical use of a dpp-4 inhibitor |
| US10285973B2 (en) | 2014-11-10 | 2019-05-14 | Merck Sharp & Dohme Corp. | SGLT-2 inhibitors for treating metabolic disorders in patients with renal impairment or chronic kidney disease |
| BR112018016001A2 (en) * | 2016-03-16 | 2018-12-18 | Boehringer Ingelheim International Gmbh | pharmaceutical composition, treatment methods and uses thereof |
| CN111163782A (zh) | 2017-10-02 | 2020-05-15 | 普克塞尔公司 | 治疗射血分数保留型心力衰竭的方法 |
| MY203360A (en) | 2018-06-06 | 2024-06-26 | Metavant Sciences Gmbh | Methods of treating subjects having diabetes with chronic kidney disease |
-
2018
- 2018-10-02 CN CN201880063705.4A patent/CN111163782A/zh active Pending
- 2018-10-02 MX MX2020003243A patent/MX2020003243A/es unknown
- 2018-10-02 KR KR1020207011597A patent/KR20200102982A/ko not_active Ceased
- 2018-10-02 JP JP2020539153A patent/JP2020536121A/ja active Pending
- 2018-10-02 CA CA3078163A patent/CA3078163A1/en active Pending
- 2018-10-02 EP EP18792513.6A patent/EP3691650A1/en not_active Withdrawn
- 2018-10-02 WO PCT/IB2018/057648 patent/WO2019069230A1/en not_active Ceased
- 2018-10-02 BR BR112020006472-6A patent/BR112020006472A2/pt not_active IP Right Cessation
- 2018-10-02 US US16/652,911 patent/US11617754B2/en active Active
- 2018-10-02 TW TW107134796A patent/TW201924689A/zh unknown
-
2020
- 2020-03-31 IL IL273723A patent/IL273723A/en unknown
- 2020-05-04 ZA ZA2020/02292A patent/ZA202002292B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019069230A1 (en) | 2019-04-11 |
| CA3078163A1 (en) | 2019-04-11 |
| IL273723A (en) | 2020-05-31 |
| CN111163782A (zh) | 2020-05-15 |
| TW201924689A (zh) | 2019-07-01 |
| US11617754B2 (en) | 2023-04-04 |
| US20200316078A1 (en) | 2020-10-08 |
| MX2020003243A (es) | 2020-09-18 |
| JP2020536121A (ja) | 2020-12-10 |
| KR20200102982A (ko) | 2020-09-01 |
| EP3691650A1 (en) | 2020-08-12 |
| BR112020006472A2 (pt) | 2020-10-06 |
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