ZA201804528B - Method for processing solutions of biomolecules - Google Patents
Method for processing solutions of biomoleculesInfo
- Publication number
- ZA201804528B ZA201804528B ZA2018/04528A ZA201804528A ZA201804528B ZA 201804528 B ZA201804528 B ZA 201804528B ZA 2018/04528 A ZA2018/04528 A ZA 2018/04528A ZA 201804528 A ZA201804528 A ZA 201804528A ZA 201804528 B ZA201804528 B ZA 201804528B
- Authority
- ZA
- South Africa
- Prior art keywords
- biomolecules
- processing solutions
- mixing
- biomolecule
- liquids
- Prior art date
Links
- 239000007788 liquid Substances 0.000 abstract 3
- 238000009295 crossflow filtration Methods 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/18—Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/145—Ultrafiltration
- B01D61/146—Ultrafiltration comprising multiple ultrafiltration steps
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/16—Feed pretreatment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/20—Accessories; Auxiliary operations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/145—Extraction; Separation; Purification by extraction or solubilisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1017—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by filtration, e.g. using filters, frits, membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/18—Specific valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/19—Specific flow restrictors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/24—Specific pressurizing or depressurizing means
- B01D2313/243—Pumps
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2315/00—Details relating to the membrane module operation
- B01D2315/10—Cross-flow filtration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2315/00—Details relating to the membrane module operation
- B01D2315/16—Diafiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2317/00—Membrane module arrangements within a plant or an apparatus
- B01D2317/02—Elements in series
- B01D2317/022—Reject series
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2319/00—Membrane assemblies within one housing
- B01D2319/02—Elements in series
- B01D2319/022—Reject series
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
- B01D2321/20—By influencing the flow
- B01D2321/2008—By influencing the flow statically
- B01D2321/2016—Static mixers; Turbulence generators
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
- B01D2321/20—By influencing the flow
- B01D2321/2066—Pulsated flow
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/22—Controlling or regulating
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Peptides Or Proteins (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Extraction Or Liquid Replacement (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1600290.9A GB201600290D0 (en) | 2016-01-07 | 2016-01-07 | Process |
| PCT/GB2016/053981 WO2017118836A1 (en) | 2016-01-07 | 2016-12-19 | Method for processing solutions of biomolecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201804528B true ZA201804528B (en) | 2024-08-28 |
Family
ID=55445684
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2018/04528A ZA201804528B (en) | 2016-01-07 | 2018-07-06 | Method for processing solutions of biomolecules |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10682610B2 (https=) |
| EP (2) | EP3400092B1 (https=) |
| JP (1) | JP7080815B2 (https=) |
| KR (1) | KR102794486B1 (https=) |
| CN (1) | CN108883368B (https=) |
| AU (1) | AU2016384286B2 (https=) |
| CA (1) | CA3010545C (https=) |
| ES (1) | ES2971100T3 (https=) |
| GB (1) | GB201600290D0 (https=) |
| RU (1) | RU2750304C2 (https=) |
| SG (1) | SG11201805688XA (https=) |
| WO (1) | WO2017118836A1 (https=) |
| ZA (1) | ZA201804528B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3466432T (lt) | 2014-05-15 | 2020-12-28 | Insmed Incorporated | Būdai, skirti plaučių netuberkuliozinėms mikobakterinėms infekcijoms gydyti |
| GB201600290D0 (en) * | 2016-01-07 | 2016-02-24 | Fujifilm Diosynth Biotechnologies Uk Ltd | Process |
| GB201802593D0 (en) * | 2018-02-16 | 2018-04-04 | Fujifilm Diosynth Biotechnologies Uk Ltd | Rig |
| EP3773505B1 (en) | 2018-03-30 | 2026-04-29 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
| JP7449275B2 (ja) | 2018-05-02 | 2024-03-13 | インスメッド インコーポレイテッド | リポソーム薬物製剤の製造方法 |
| US20210253633A1 (en) * | 2018-06-08 | 2021-08-19 | Bristol-Myers Squibb Company | Single pass tangential flow filtration hybrid configurations for enhancing concentration of macromolecule solutions |
| GB201911686D0 (en) * | 2019-08-15 | 2019-10-02 | Fujifilm Diosynth Biotechnologies Uk Ltd | Process for purifying target substances |
| GB201911685D0 (en) * | 2019-08-15 | 2019-10-02 | Fujifilm Diosynth Biotechnologies Uk Ltd | Process for purifying monoclonal antibodies |
| CN110968509B (zh) * | 2019-11-25 | 2022-11-29 | 苏宁云计算有限公司 | 一种批量化自定义变量的方法和系统 |
| GB201918890D0 (en) | 2019-12-19 | 2020-02-05 | Ge Healthcare Bio Sciences Ab | A bioprocess fluid mixing system |
| CN114262357B (zh) * | 2021-12-29 | 2023-08-11 | 浙江旅游职业学院 | 一种基于ph偏移技术的亚麻蛋白改性设备及方法 |
| CN119173331A (zh) * | 2022-03-21 | 2024-12-20 | 建新公司 | 处理流体的方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3726613A (en) | 1970-10-12 | 1973-04-10 | Casimir W Von | Pulsefree peristaltic pump |
| DE2223354A1 (de) | 1972-05-12 | 1973-11-29 | Wolf Von Dipl Phys Casimir | Verfahren und vorrichtung zur glaettung der foerderleistung von schlauchpumpen |
| JPS58190447A (ja) * | 1982-04-30 | 1983-11-07 | 株式会社クラレ | 脈動発生装置 |
| SU1655546A1 (ru) * | 1989-06-21 | 1991-06-15 | Всесоюзный научно-исследовательский проектно-конструкторский институт прикладной биохимии | Установка дл концентрировани культурной жидкости |
| FR2737261B1 (fr) | 1995-07-27 | 1997-10-10 | Jean Francois Ognier | Pompe peristaltique |
| US6011148A (en) | 1996-08-01 | 2000-01-04 | Megabios Corporation | Methods for purifying nucleic acids |
| US20040256329A1 (en) | 2003-06-13 | 2004-12-23 | Peter Meserol | Photodynamic biological fluid pathogen inactivation/filtering apparatus and method |
| US7384549B2 (en) | 2005-12-29 | 2008-06-10 | Spf Innovations, Llc | Method and apparatus for the filtration of biological solutions |
| WO2010090864A2 (en) * | 2009-01-21 | 2010-08-12 | Smartflow Technologies, Inc. | Optimization of separation for viscous suspensions |
| US20130040282A1 (en) * | 2009-06-15 | 2013-02-14 | Biovec Transfusion, Llc | Device and method for removing additives in the blood products |
| US10265388B2 (en) | 2012-02-21 | 2019-04-23 | Cytonics Corporation | Systems, compositions, and methods for transplantation |
| EP2698162A1 (en) | 2012-08-15 | 2014-02-19 | Credentis AG | Method for producing a composition for treating a tooth lesion |
| US9533899B2 (en) * | 2013-03-12 | 2017-01-03 | General Electric Company | Gasification waste water treatment using air separation unit oxygen |
| EP3113865A4 (en) * | 2014-03-07 | 2017-11-01 | Agency For Science, Technology And Research | Apparatus and methods for fractionation of biological products |
| US10324070B2 (en) * | 2014-04-23 | 2019-06-18 | Chromatan Inc. | High efficiency continuous countercurrent tangential chromatography |
| CN107106701B (zh) | 2014-10-03 | 2020-11-06 | 西纳福克斯股份有限公司 | 磺酰胺接头、其缀合物及制备方法 |
| WO2017062622A1 (en) | 2015-10-06 | 2017-04-13 | Massachusetts Institute Of Technology | Supramolecular modification of proteins |
| GB201600290D0 (en) * | 2016-01-07 | 2016-02-24 | Fujifilm Diosynth Biotechnologies Uk Ltd | Process |
-
2016
- 2016-01-07 GB GBGB1600290.9A patent/GB201600290D0/en not_active Ceased
- 2016-12-19 CA CA3010545A patent/CA3010545C/en active Active
- 2016-12-19 RU RU2018128572A patent/RU2750304C2/ru active
- 2016-12-19 EP EP16816370.7A patent/EP3400092B1/en active Active
- 2016-12-19 CN CN201680083264.5A patent/CN108883368B/zh active Active
- 2016-12-19 ES ES16816370T patent/ES2971100T3/es active Active
- 2016-12-19 WO PCT/GB2016/053981 patent/WO2017118836A1/en not_active Ceased
- 2016-12-19 KR KR1020187022653A patent/KR102794486B1/ko active Active
- 2016-12-19 AU AU2016384286A patent/AU2016384286B2/en active Active
- 2016-12-19 EP EP23185630.3A patent/EP4273154A3/en active Pending
- 2016-12-19 SG SG11201805688XA patent/SG11201805688XA/en unknown
- 2016-12-19 JP JP2018535310A patent/JP7080815B2/ja active Active
- 2016-12-19 US US16/068,465 patent/US10682610B2/en active Active
-
2018
- 2018-07-06 ZA ZA2018/04528A patent/ZA201804528B/en unknown
-
2020
- 2020-05-01 US US16/864,234 patent/US11439956B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2971100T3 (es) | 2024-06-03 |
| CN108883368B (zh) | 2021-12-31 |
| CA3010545A1 (en) | 2017-07-13 |
| RU2018128572A3 (https=) | 2020-02-07 |
| US10682610B2 (en) | 2020-06-16 |
| AU2016384286B2 (en) | 2022-03-17 |
| US20190009215A1 (en) | 2019-01-10 |
| SG11201805688XA (en) | 2018-07-30 |
| EP3400092C0 (en) | 2023-11-22 |
| GB201600290D0 (en) | 2016-02-24 |
| RU2750304C2 (ru) | 2021-06-25 |
| EP3400092A1 (en) | 2018-11-14 |
| EP3400092B1 (en) | 2023-11-22 |
| CN108883368A (zh) | 2018-11-23 |
| AU2016384286A1 (en) | 2018-07-19 |
| JP7080815B2 (ja) | 2022-06-06 |
| RU2018128572A (ru) | 2020-02-07 |
| EP4273154A3 (en) | 2023-12-06 |
| KR20180100411A (ko) | 2018-09-10 |
| US20200269190A1 (en) | 2020-08-27 |
| WO2017118836A1 (en) | 2017-07-13 |
| CA3010545C (en) | 2023-10-03 |
| US11439956B2 (en) | 2022-09-13 |
| JP2019511453A (ja) | 2019-04-25 |
| EP4273154A2 (en) | 2023-11-08 |
| KR102794486B1 (ko) | 2025-04-11 |
| BR112018013650A2 (pt) | 2019-01-22 |
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