ZA201701526B - Methods of treating depression using nmda modulators - Google Patents

Methods of treating depression using nmda modulators

Info

Publication number
ZA201701526B
ZA201701526B ZA2017/01526A ZA201701526A ZA201701526B ZA 201701526 B ZA201701526 B ZA 201701526B ZA 2017/01526 A ZA2017/01526 A ZA 2017/01526A ZA 201701526 A ZA201701526 A ZA 201701526A ZA 201701526 B ZA201701526 B ZA 201701526B
Authority
ZA
South Africa
Prior art keywords
methods
treating depression
nmda modulators
nmda
modulators
Prior art date
Application number
ZA2017/01526A
Other languages
English (en)
Inventor
Ron Burch
Original Assignee
Naurex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Naurex Inc filed Critical Naurex Inc
Publication of ZA201701526B publication Critical patent/ZA201701526B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA2017/01526A 2014-08-14 2017-03-01 Methods of treating depression using nmda modulators ZA201701526B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462037374P 2014-08-14 2014-08-14
PCT/US2015/045071 WO2016025721A1 (en) 2014-08-14 2015-08-13 Methods of treating depression using nmda modulators

Publications (1)

Publication Number Publication Date
ZA201701526B true ZA201701526B (en) 2018-05-30

Family

ID=55304631

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2017/01526A ZA201701526B (en) 2014-08-14 2017-03-01 Methods of treating depression using nmda modulators

Country Status (18)

Country Link
US (1) US20170296616A1 (enExample)
EP (1) EP3180015A4 (enExample)
JP (2) JP2017524721A (enExample)
KR (1) KR20170040351A (enExample)
CN (1) CN106659763A (enExample)
AU (2) AU2015301650A1 (enExample)
BR (1) BR112017002930A2 (enExample)
CA (1) CA2957937A1 (enExample)
CL (1) CL2017000378A1 (enExample)
CO (1) CO2017002356A2 (enExample)
IL (1) IL250557A0 (enExample)
MX (1) MX2017002052A (enExample)
PH (1) PH12017500275A1 (enExample)
RU (1) RU2017107033A (enExample)
SG (2) SG10201810016XA (enExample)
UA (1) UA123623C2 (enExample)
WO (1) WO2016025721A1 (enExample)
ZA (1) ZA201701526B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3362080A1 (en) * 2015-10-16 2018-08-22 Northwestern University Pharmaceutical combination of an atypical antipsychotic and an nmda modulator for the treatment of schizophrenia,bipolar disorder, cognitive impairment and major depressive disorder
US10487055B2 (en) 2016-06-01 2019-11-26 Rhode Island Board Of Education Diindole compounds useful in treatment of nervous system disorders
US11358935B2 (en) 2016-11-28 2022-06-14 Biohaven Pharmaceutical Holding Company Ltd. Prodrugs of lanicemine and their method of use
WO2018234568A2 (en) * 2017-06-23 2018-12-27 Develco Pharma Schweiz Ag Hydroxynorketamine for the use in the treatment of depression
WO2019094676A1 (en) * 2017-11-10 2019-05-16 Naurex Inc. Methods of administration of nmda receptor agonists
EP3720464A1 (en) * 2017-12-05 2020-10-14 Naurex Inc. Nmda receptor modulators (rapastinel) combination for use in combined treatment (sleep and cns disorder)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4086196A (en) 1975-03-28 1978-04-25 Armour Pharmaceutical Company Parathyroid hormone
US5763393A (en) 1996-05-17 1998-06-09 Neurotherapeutics L.P. Neuroactive peptides
US8951968B2 (en) * 2009-10-05 2015-02-10 Northwestern University Methods of treating depression and other related diseases
HRP20140784T1 (hr) * 2009-10-05 2014-10-10 Northwestern University Glyx-13 za uporabu u postupku tretiranja refraktornih depresija
US9737531B2 (en) * 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans

Also Published As

Publication number Publication date
KR20170040351A (ko) 2017-04-12
EP3180015A4 (en) 2018-02-14
EP3180015A1 (en) 2017-06-21
WO2016025721A1 (en) 2016-02-18
AU2015301650A1 (en) 2017-03-23
CA2957937A1 (en) 2016-02-18
IL250557A0 (en) 2017-03-30
BR112017002930A2 (pt) 2017-12-05
SG10201810016XA (en) 2018-12-28
CO2017002356A2 (es) 2017-06-09
RU2017107033A3 (enExample) 2019-02-12
US20170296616A1 (en) 2017-10-19
MX2017002052A (es) 2018-08-15
JP2020128391A (ja) 2020-08-27
CN106659763A (zh) 2017-05-10
PH12017500275A1 (en) 2017-07-03
RU2017107033A (ru) 2018-09-14
SG11201701134XA (en) 2017-03-30
JP2017524721A (ja) 2017-08-31
AU2020203165A1 (en) 2020-06-04
UA123623C2 (uk) 2021-05-05
CL2017000378A1 (es) 2017-11-03

Similar Documents

Publication Publication Date Title
IL286669A (en) Compounds and methods for modulating tmprss6 expression
IL279627A (en) A method for treating depression
IL259421B (en) ror - gamma modulators
ZA201802663B (en) Modulators of kras expression
SG11201700070QA (en) Modulators of toll-like receptors for the treatment of hiv
IL264482A (en) Spiro-lactam nmda modulators and methods of their use
EP3116851A4 (en) Analogs of fexaramine and methods of making and using
IL247847B (en) ror gamma modulator and their use
ZA201605332B (en) Trpa1 modulators
PL3303293T3 (pl) Modulatory ROR-gamma
PL3303291T3 (pl) Modulatory ROR-gamma
PL3303290T3 (pl) Modulatory ROR-gamma
ZA201701526B (en) Methods of treating depression using nmda modulators
PL3319942T3 (pl) MODULATORY ROR-GAMMA (RORγ)
GB201416832D0 (en) Methods of treatment
IL249434B (en) Use of active negative modulators of erythropoietin for treatment
EP3171941A4 (en) N-methyl-d-aspartate receptor modulators and methods of making and using same
EP3105471A4 (en) Apparatus for use of chain
IL247234A0 (en) Caspase-6 modulators
SG11201607445QA (en) Methods of modulating wars2
AU362355S (en) Surface-treatment apparatus
GB201413982D0 (en) Bridge distribution apparatus
HK1238136A1 (en) Methods of treating depression using nmda modulators
GB2524547B (en) Delta Sigma modulators
GB201400215D0 (en) Modulators