UA123623C2 - Способи лікування депресії із застосуванням модуляторів nmda - Google Patents

Способи лікування депресії із застосуванням модуляторів nmda Download PDF

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Publication number
UA123623C2
UA123623C2 UAA201702145A UAA201702145A UA123623C2 UA 123623 C2 UA123623 C2 UA 123623C2 UA A201702145 A UAA201702145 A UA A201702145A UA A201702145 A UAA201702145 A UA A201702145A UA 123623 C2 UA123623 C2 UA 123623C2
Authority
UA
Ukraine
Prior art keywords
weeks
patient
period
during
depression
Prior art date
Application number
UAA201702145A
Other languages
English (en)
Ukrainian (uk)
Inventor
Рон Бйорч
Original Assignee
Наурекс, Інк.
Наурекс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Наурекс, Інк., Наурекс, Инк. filed Critical Наурекс, Інк.
Publication of UA123623C2 publication Critical patent/UA123623C2/uk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
UAA201702145A 2014-08-14 2015-08-13 Способи лікування депресії із застосуванням модуляторів nmda UA123623C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462037374P 2014-08-14 2014-08-14
PCT/US2015/045071 WO2016025721A1 (en) 2014-08-14 2015-08-13 Methods of treating depression using nmda modulators

Publications (1)

Publication Number Publication Date
UA123623C2 true UA123623C2 (uk) 2021-05-05

Family

ID=55304631

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201702145A UA123623C2 (uk) 2014-08-14 2015-08-13 Способи лікування депресії із застосуванням модуляторів nmda

Country Status (18)

Country Link
US (1) US20170296616A1 (enExample)
EP (1) EP3180015A4 (enExample)
JP (2) JP2017524721A (enExample)
KR (1) KR20170040351A (enExample)
CN (1) CN106659763A (enExample)
AU (2) AU2015301650A1 (enExample)
BR (1) BR112017002930A2 (enExample)
CA (1) CA2957937A1 (enExample)
CL (1) CL2017000378A1 (enExample)
CO (1) CO2017002356A2 (enExample)
IL (1) IL250557A0 (enExample)
MX (1) MX2017002052A (enExample)
PH (1) PH12017500275A1 (enExample)
RU (1) RU2017107033A (enExample)
SG (2) SG10201810016XA (enExample)
UA (1) UA123623C2 (enExample)
WO (1) WO2016025721A1 (enExample)
ZA (1) ZA201701526B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180102052A (ko) * 2015-10-16 2018-09-14 노오쓰웨스턴 유니버시티 조현병, 양극성 장애, 인지 손상 및 주요 우울 장애의 치료를 위한 비전형적 항정신병약과 nmda 조절제의 약제학적 병용
US10487055B2 (en) 2016-06-01 2019-11-26 Rhode Island Board Of Education Diindole compounds useful in treatment of nervous system disorders
US11358935B2 (en) 2016-11-28 2022-06-14 Biohaven Pharmaceutical Holding Company Ltd. Prodrugs of lanicemine and their method of use
EP3706734A1 (en) * 2017-11-10 2020-09-16 Naurex Inc. Methods of administration of nmda receptor agonists
US20200368310A1 (en) * 2017-12-05 2020-11-26 Naurex, INC Treatment with nmda receptor modulators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4086196A (en) 1975-03-28 1978-04-25 Armour Pharmaceutical Company Parathyroid hormone
US5763393A (en) 1996-05-17 1998-06-09 Neurotherapeutics L.P. Neuroactive peptides
EP2485751B1 (en) * 2009-10-05 2014-05-21 Northwestern University GLYX-13 for use in a method of treating refractory depression
US8951968B2 (en) * 2009-10-05 2015-02-10 Northwestern University Methods of treating depression and other related diseases
US9737531B2 (en) * 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans

Also Published As

Publication number Publication date
BR112017002930A2 (pt) 2017-12-05
CL2017000378A1 (es) 2017-11-03
SG10201810016XA (en) 2018-12-28
MX2017002052A (es) 2018-08-15
EP3180015A4 (en) 2018-02-14
JP2020128391A (ja) 2020-08-27
IL250557A0 (en) 2017-03-30
CO2017002356A2 (es) 2017-06-09
AU2015301650A1 (en) 2017-03-23
PH12017500275A1 (en) 2017-07-03
ZA201701526B (en) 2018-05-30
EP3180015A1 (en) 2017-06-21
JP2017524721A (ja) 2017-08-31
SG11201701134XA (en) 2017-03-30
RU2017107033A3 (enExample) 2019-02-12
KR20170040351A (ko) 2017-04-12
US20170296616A1 (en) 2017-10-19
CA2957937A1 (en) 2016-02-18
RU2017107033A (ru) 2018-09-14
AU2020203165A1 (en) 2020-06-04
WO2016025721A1 (en) 2016-02-18
CN106659763A (zh) 2017-05-10

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