ZA201608331B - Aminoester derivatives - Google Patents

Aminoester derivatives

Info

Publication number
ZA201608331B
ZA201608331B ZA2016/08331A ZA201608331A ZA201608331B ZA 201608331 B ZA201608331 B ZA 201608331B ZA 2016/08331 A ZA2016/08331 A ZA 2016/08331A ZA 201608331 A ZA201608331 A ZA 201608331A ZA 201608331 B ZA201608331 B ZA 201608331B
Authority
ZA
South Africa
Prior art keywords
aminoester derivatives
aminoester
derivatives
Prior art date
Application number
ZA2016/08331A
Other languages
English (en)
Inventor
Armani Elisabetta
Amari Gabriele
Capaldi Carmelida
Blackaby Wesley
Linney Ian
Van De Pöel Hervé
Baker-Glenn Charles
Trivedi Naimisha
Original Assignee
Chiesi Farmaceutici S P A An Incorporated Business Forming A Joint Stock Company Of Italian Nat
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farmaceutici S P A An Incorporated Business Forming A Joint Stock Company Of Italian Nat filed Critical Chiesi Farmaceutici S P A An Incorporated Business Forming A Joint Stock Company Of Italian Nat
Publication of ZA201608331B publication Critical patent/ZA201608331B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA2016/08331A 2014-06-05 2016-12-02 Aminoester derivatives ZA201608331B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14171266 2014-06-05
PCT/EP2015/062417 WO2015185649A1 (en) 2014-06-05 2015-06-03 Aminoester derivatives

Publications (1)

Publication Number Publication Date
ZA201608331B true ZA201608331B (en) 2018-05-30

Family

ID=50884281

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2016/08331A ZA201608331B (en) 2014-06-05 2016-12-02 Aminoester derivatives

Country Status (32)

Country Link
US (2) US9763924B2 (cg-RX-API-DMAC7.html)
EP (1) EP3152201B1 (cg-RX-API-DMAC7.html)
JP (1) JP2017516824A (cg-RX-API-DMAC7.html)
KR (1) KR102420323B1 (cg-RX-API-DMAC7.html)
CN (1) CN106459020B (cg-RX-API-DMAC7.html)
AR (1) AR100732A1 (cg-RX-API-DMAC7.html)
AU (1) AU2015270539B2 (cg-RX-API-DMAC7.html)
BR (1) BR112016026725B1 (cg-RX-API-DMAC7.html)
CA (1) CA2953198C (cg-RX-API-DMAC7.html)
CL (1) CL2016003117A1 (cg-RX-API-DMAC7.html)
CY (1) CY1120698T1 (cg-RX-API-DMAC7.html)
DK (1) DK3152201T3 (cg-RX-API-DMAC7.html)
EA (1) EA032761B1 (cg-RX-API-DMAC7.html)
ES (1) ES2688826T3 (cg-RX-API-DMAC7.html)
GE (1) GEP20186922B (cg-RX-API-DMAC7.html)
HR (1) HRP20181967T1 (cg-RX-API-DMAC7.html)
HU (1) HUE042119T2 (cg-RX-API-DMAC7.html)
IL (1) IL249325B (cg-RX-API-DMAC7.html)
LT (1) LT3152201T (cg-RX-API-DMAC7.html)
MA (1) MA39947B1 (cg-RX-API-DMAC7.html)
MX (1) MX377669B (cg-RX-API-DMAC7.html)
PE (1) PE20161557A1 (cg-RX-API-DMAC7.html)
PH (1) PH12016502221A1 (cg-RX-API-DMAC7.html)
PL (1) PL3152201T3 (cg-RX-API-DMAC7.html)
PT (1) PT3152201T (cg-RX-API-DMAC7.html)
RS (1) RS57787B1 (cg-RX-API-DMAC7.html)
SG (1) SG11201610132RA (cg-RX-API-DMAC7.html)
SI (1) SI3152201T1 (cg-RX-API-DMAC7.html)
TN (1) TN2016000546A1 (cg-RX-API-DMAC7.html)
TW (1) TW201625600A (cg-RX-API-DMAC7.html)
WO (1) WO2015185649A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201608331B (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016177849A1 (en) 2015-05-07 2016-11-10 Chiesi Farmaceutici S.P.A. Aminoester derivatives
AR104822A1 (es) * 2015-06-01 2017-08-16 Chiesi Farm Spa Derivado de aminoésteres
TW201710254A (zh) * 2015-06-01 2017-03-16 吉斯藥品公司 胺基酯衍生物
CN106866474B (zh) * 2017-02-16 2018-12-28 陕西师范大学 一种手性α-芳基甘氨酸酯衍生物的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2022783A1 (en) 2007-08-08 2009-02-11 CHIESI FARMACEUTICI S.p.A. "Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors"
AR070562A1 (es) 2008-02-06 2010-04-21 Glaxo Group Ltd Farmacoforos duales - antagonistas muscarinicos de pde4
EP2216327A1 (en) * 2009-02-06 2010-08-11 CHIESI FARMACEUTICI S.p.A. Benzoic acid (1-phenyl-2-pyridin-4-yl)ethyl esters as phosphodiesterase inhibitors
WO2014086849A1 (en) 2012-12-05 2014-06-12 Chiesi Farmaceutici S.P.A. Phenylethylpyridine derivatives as pde4-inhibitors
HK1213245A1 (zh) 2012-12-05 2016-06-30 奇斯药制品公司 作为pde4抑制剂的苯乙基吡啶衍生物
TW201439089A (zh) 2012-12-05 2014-10-16 Chiesi Farma Spa 新穎化合物
CA2932487A1 (en) 2013-12-05 2015-06-11 Chiesi Farmaceutici S.P.A. Heteroaryl derivatives for the treatment of respiratory diseases
EP3077386B1 (en) 2013-12-05 2017-09-06 Chiesi Farmaceutici S.p.A. Benzhydryl derivatives for the treatment of respiratory diseases

Also Published As

Publication number Publication date
IL249325B (en) 2018-12-31
US20170340616A1 (en) 2017-11-30
AR100732A1 (es) 2016-10-26
SI3152201T1 (sl) 2018-10-30
GEP20186922B (en) 2018-11-12
CN106459020B (zh) 2019-06-18
HUE042119T2 (hu) 2019-06-28
KR102420323B1 (ko) 2022-07-13
CN106459020A (zh) 2017-02-22
LT3152201T (lt) 2018-10-10
ES2688826T3 (es) 2018-11-07
EA032761B1 (ru) 2019-07-31
BR112016026725B1 (pt) 2024-02-27
EP3152201B1 (en) 2018-08-29
US10117860B2 (en) 2018-11-06
US9763924B2 (en) 2017-09-19
DK3152201T3 (en) 2018-11-19
EP3152201A1 (en) 2017-04-12
BR112016026725A2 (pt) 2017-08-15
TN2016000546A1 (en) 2018-04-04
MA39947B1 (fr) 2018-10-31
KR20170015294A (ko) 2017-02-08
MX377669B (es) 2025-03-11
EA201692227A1 (ru) 2017-05-31
PT3152201T (pt) 2018-10-26
HRP20181967T1 (hr) 2019-02-08
PH12016502221A1 (en) 2017-02-06
PE20161557A1 (es) 2017-02-07
CL2016003117A1 (es) 2017-06-23
CY1120698T1 (el) 2019-12-11
WO2015185649A9 (en) 2017-01-05
RS57787B1 (sr) 2018-12-31
JP2017516824A (ja) 2017-06-22
PL3152201T3 (pl) 2019-02-28
AU2015270539B2 (en) 2018-11-08
MA39947A (fr) 2017-04-12
WO2015185649A1 (en) 2015-12-10
CA2953198A1 (en) 2015-12-10
TW201625600A (zh) 2016-07-16
BR112016026725A8 (pt) 2021-06-29
US20150352091A1 (en) 2015-12-10
IL249325A0 (en) 2017-02-28
CA2953198C (en) 2023-06-13
AU2015270539A1 (en) 2016-12-22
SG11201610132RA (en) 2017-01-27
MX2016015958A (es) 2017-04-10

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