ZA201408043B - Pyrrolobenzodiazepines - Google Patents

Pyrrolobenzodiazepines

Info

Publication number
ZA201408043B
ZA201408043B ZA2014/08043A ZA201408043A ZA201408043B ZA 201408043 B ZA201408043 B ZA 201408043B ZA 2014/08043 A ZA2014/08043 A ZA 2014/08043A ZA 201408043 A ZA201408043 A ZA 201408043A ZA 201408043 B ZA201408043 B ZA 201408043B
Authority
ZA
South Africa
Prior art keywords
pyrrolobenzodiazepines
Prior art date
Application number
ZA2014/08043A
Other languages
English (en)
Inventor
Peter William Taylor
Khondaker Mirazur Rahman
David Edwin Thurston
Philip Wilson Howard
Original Assignee
Ucl Business Plc
Spirogen Sàrl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucl Business Plc, Spirogen Sàrl filed Critical Ucl Business Plc
Publication of ZA201408043B publication Critical patent/ZA201408043B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA2014/08043A 2012-04-30 2014-11-04 Pyrrolobenzodiazepines ZA201408043B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261640316P 2012-04-30 2012-04-30
PCT/GB2013/051097 WO2013164592A1 (en) 2012-04-30 2013-04-30 Pyrrolobenzodiazepines

Publications (1)

Publication Number Publication Date
ZA201408043B true ZA201408043B (en) 2017-08-30

Family

ID=48289484

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2014/08043A ZA201408043B (en) 2012-04-30 2014-11-04 Pyrrolobenzodiazepines

Country Status (14)

Country Link
US (1) US9321774B2 (enExample)
EP (1) EP2855481A1 (enExample)
JP (1) JP6125614B2 (enExample)
KR (1) KR101960130B1 (enExample)
CN (1) CN104540827B (enExample)
AU (1) AU2013255612B2 (enExample)
BR (1) BR112014027190B1 (enExample)
CA (1) CA2872205C (enExample)
HK (1) HK1208217A1 (enExample)
IN (1) IN2014MN02175A (enExample)
MX (1) MX2014013144A (enExample)
NZ (1) NZ701478A (enExample)
WO (1) WO2013164592A1 (enExample)
ZA (1) ZA201408043B (enExample)

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GB201702031D0 (en) 2017-02-08 2017-03-22 Medlmmune Ltd Pyrrolobenzodiazepine-antibody conjugates
EP3544636B1 (en) 2017-02-08 2021-03-31 ADC Therapeutics SA Pyrrolobenzodiazepine-antibody conjugates
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US11318211B2 (en) 2017-06-14 2022-05-03 Adc Therapeutics Sa Dosage regimes for the administration of an anti-CD19 ADC
EA039276B1 (ru) 2017-08-18 2021-12-27 Медимьюн Лимитед Пирролобензодиазепиновые конъюгаты
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EP3717021A1 (en) 2017-11-27 2020-10-07 Mersana Therapeutics, Inc. Pyrrolobenzodiazepine antibody conjugates
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GB201900929D0 (en) * 2019-01-23 2019-03-13 King S College London Nf-kappa b inhibitors
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WO2024005123A1 (ja) 2022-06-30 2024-01-04 東レ株式会社 癌の治療及び／又は予防用医薬組成物
CN121002040A (zh) 2022-12-14 2025-11-21 费恩治疗有限公司 细胞毒性化合物
WO2025262641A1 (en) 2024-06-19 2025-12-26 Pheon Therapeutics Ltd Antibody drug conjugates that bind cdcp1 and uses thereof

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Also Published As

Publication number Publication date
CA2872205C (en) 2020-07-21
BR112014027190B1 (pt) 2020-03-03
WO2013164592A1 (en) 2013-11-07
KR20150014935A (ko) 2015-02-09
JP2015516987A (ja) 2015-06-18
MX2014013144A (es) 2015-05-11
US20150126495A1 (en) 2015-05-07
CA2872205A1 (en) 2013-11-07
CN104540827A (zh) 2015-04-22
NZ701478A (en) 2016-08-26
AU2013255612A1 (en) 2014-11-20
JP6125614B2 (ja) 2017-05-10
US9321774B2 (en) 2016-04-26
CN104540827B (zh) 2018-03-23
BR112014027190A2 (pt) 2017-06-27
HK1208217A1 (en) 2016-02-26
KR101960130B1 (ko) 2019-03-19
IN2014MN02175A (enExample) 2015-08-28
EP2855481A1 (en) 2015-04-08
AU2013255612B2 (en) 2017-06-22

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