ZA201401789B - Process for the preparation of complexes of 68ga - Google Patents

Process for the preparation of complexes of 68ga

Info

Publication number
ZA201401789B
ZA201401789B ZA2014/01789A ZA201401789A ZA201401789B ZA 201401789 B ZA201401789 B ZA 201401789B ZA 2014/01789 A ZA2014/01789 A ZA 2014/01789A ZA 201401789 A ZA201401789 A ZA 201401789A ZA 201401789 B ZA201401789 B ZA 201401789B
Authority
ZA
South Africa
Prior art keywords
complexes
preparation
Prior art date
Application number
ZA2014/01789A
Other languages
English (en)
Inventor
Lorenza Fugazza
Maurizio Franco Mariani
Maria Azzurra Filammino
Original Assignee
Advanced Accelerator Applications S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Accelerator Applications S A filed Critical Advanced Accelerator Applications S A
Publication of ZA201401789B publication Critical patent/ZA201401789B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008Peptides; Proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA2014/01789A 2011-08-12 2014-03-11 Process for the preparation of complexes of 68ga ZA201401789B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000180A ITFI20110180A1 (it) 2011-08-12 2011-08-12 Processo per la preparazione di complessi di 68ga.
PCT/EP2012/065659 WO2013024013A2 (en) 2011-08-12 2012-08-10 Process for the preparation of complexes of 68ga.

Publications (1)

Publication Number Publication Date
ZA201401789B true ZA201401789B (en) 2015-01-28

Family

ID=44898621

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2014/01789A ZA201401789B (en) 2011-08-12 2014-03-11 Process for the preparation of complexes of 68ga

Country Status (19)

Country Link
US (2) US9375498B2 (https=)
EP (3) EP3718991A1 (https=)
JP (1) JP6161610B2 (https=)
CN (1) CN103889930B (https=)
AU (1) AU2012297008B2 (https=)
BR (2) BR112014003336B1 (https=)
CA (2) CA3045484C (https=)
CO (1) CO7020857A2 (https=)
DK (1) DK2742017T3 (https=)
ES (2) ES2560231T3 (https=)
IL (3) IL230904B (https=)
IN (1) IN2014CN01897A (https=)
IT (1) ITFI20110180A1 (https=)
MX (1) MX370081B (https=)
PL (1) PL2742017T3 (https=)
PT (1) PT2742017E (https=)
RU (2) RU2605090C2 (https=)
WO (1) WO2013024013A2 (https=)
ZA (1) ZA201401789B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11027030B2 (en) 2014-08-29 2021-06-08 Anmi S.A. Kit for radiolabelling
BE1021191B1 (fr) 2014-08-29 2015-10-27 Anmi S.A. Kit pour radiomarquage.
CN107405538B (zh) * 2015-01-30 2021-06-15 高级催化剂应用品国际有限公司 用于从来源于68Ge/68Ga发生器的洗脱物纯化Ga-68的工艺和用于所述工艺中的色谱柱
IL237525A (en) 2015-03-03 2017-05-29 Shalom Eli Method for labeling a prostate-specific membrane antigen with a radioactive isotope
GB201504064D0 (en) * 2015-03-10 2015-04-22 Accretion Biotechnology Ltd Method and kits for preparing radionuclide complexes
IL297323A (en) * 2020-04-29 2022-12-01 Novartis Ag Methods for radiological labeling of psma-binding ligands and their kits
RU2760273C1 (ru) * 2020-11-02 2021-11-23 Федеральное государственное бюджетное учреждение науки Ордена Трудового Красного Знамени Институт химии силикатов им. И.В. Гребенщикова Российской академии наук (ИХС РАН) Способ получения комплексов на основе изотопа галлий-68
EP4347541A2 (en) 2021-05-31 2024-04-10 Telix Pharmaceuticals (Innovations) Pty Ltd Improved prostate-specific membrane antigen targeting radiopharmaceuticals and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6056939A (en) * 1998-08-28 2000-05-02 Desreux; Jean F. Self-assembling heteropolymetallic chelates as imaging agents and radiopharmaceuticals
WO2003048207A2 (en) * 2001-11-28 2003-06-12 Immunomedics, Inc. Anti-dota antibody
GB0308408D0 (en) * 2003-04-11 2003-05-21 Amersham Plc Microwave activation
JP5139678B2 (ja) * 2003-07-24 2013-02-06 ブラッコ・イメージング・ソシエタ・ペル・アチオニ 安定な放射性医薬品組成物およびその製法
CN1874792A (zh) * 2003-09-03 2006-12-06 布里斯托尔-迈尔斯.斯奎布制药公司 包含基质金属蛋白酶底物的化合物及其使用方法
DE102004057225B4 (de) * 2004-11-26 2006-10-12 Johannes-Gutenberg-Universität Mainz Verfahren und Vorrichtung zur Isolierung eines chemisch und radiochemisch gereinigten 68Ga-Radionuklids und zum Markieren eines Markierungsvorläufers mit dem 68Ga-Radionuklid
EP2056886A2 (en) * 2006-08-28 2009-05-13 GE Healthcare Limited 68ga-labeled peptide-based radiopharmaceuticals
FR2942227B1 (fr) * 2009-02-13 2011-04-15 Guerbet Sa Utilisation de tampons pour la complexation de radionucleides
WO2010141833A2 (en) * 2009-06-05 2010-12-09 The General Hospital Corporation Vital fluorochrome conjugates and methods of use

Also Published As

Publication number Publication date
RU2016144237A3 (https=) 2019-10-10
CN103889930A (zh) 2014-06-25
MX2014001691A (es) 2014-11-13
WO2013024013A3 (en) 2013-05-02
US9375498B2 (en) 2016-06-28
JP6161610B2 (ja) 2017-07-12
IL230904A0 (en) 2014-03-31
MX370081B (es) 2019-11-29
CA2844145A1 (en) 2013-02-21
CA2844145C (en) 2019-07-30
IL275979B (en) 2022-10-01
PL2742017T3 (pl) 2016-04-29
ES2560231T3 (es) 2016-02-18
ITFI20110180A1 (it) 2013-02-13
NZ622071A (en) 2015-07-31
CN103889930B (zh) 2017-03-29
EP3718991A1 (en) 2020-10-07
AU2012297008B2 (en) 2016-12-08
US20160263259A1 (en) 2016-09-15
AU2012297008A1 (en) 2014-03-20
RU2605090C2 (ru) 2016-12-20
EP2742017A2 (en) 2014-06-18
CA3045484A1 (en) 2013-02-21
US20140171637A1 (en) 2014-06-19
DK2742017T3 (da) 2016-02-08
RU2016144237A (ru) 2018-12-18
EP2955168A1 (en) 2015-12-16
EP2742017B1 (en) 2015-10-28
IL230904B (en) 2019-01-31
ES2835581T3 (es) 2021-06-22
BR122020011908B1 (pt) 2022-07-05
BR112014003336B1 (pt) 2021-03-09
IN2014CN01897A (https=) 2015-05-29
IL245849A0 (en) 2016-07-31
CA3045484C (en) 2022-10-11
RU2014109381A (ru) 2015-09-20
JP2014524423A (ja) 2014-09-22
RU2020120802A (ru) 2021-12-23
PT2742017E (pt) 2016-02-26
BR112014003336A2 (pt) 2017-03-14
EP2955168B1 (en) 2020-09-23
IL245849B (en) 2021-03-25
WO2013024013A2 (en) 2013-02-21
CO7020857A2 (es) 2014-08-11
NZ708281A (en) 2016-01-29
IL275979A (en) 2020-08-31
US9907868B2 (en) 2018-03-06
IL275979B2 (en) 2023-02-01

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