ZA201209305B - Method for purifying a fused pyrrolocarbazole derivative - Google Patents

Method for purifying a fused pyrrolocarbazole derivative

Info

Publication number
ZA201209305B
ZA201209305B ZA2012/09305A ZA201209305A ZA201209305B ZA 201209305 B ZA201209305 B ZA 201209305B ZA 2012/09305 A ZA2012/09305 A ZA 2012/09305A ZA 201209305 A ZA201209305 A ZA 201209305A ZA 201209305 B ZA201209305 B ZA 201209305B
Authority
ZA
South Africa
Prior art keywords
purifying
fused pyrrolocarbazole
pyrrolocarbazole derivative
derivative
fused
Prior art date
Application number
ZA2012/09305A
Other languages
English (en)
Inventor
Shawn P Allwein
Guy Piacenza
Arnaud Grandeury
Sebastien Rose
Original Assignee
Cephalon Inc
Teva Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc, Teva Sante filed Critical Cephalon Inc
Publication of ZA201209305B publication Critical patent/ZA201209305B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA2012/09305A 2010-05-18 2012-12-07 Method for purifying a fused pyrrolocarbazole derivative ZA201209305B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34583110P 2010-05-18 2010-05-18
PCT/US2011/036814 WO2011146488A1 (en) 2010-05-18 2011-05-17 Method for purifying a fused pyrrolocarbazole derivative

Publications (1)

Publication Number Publication Date
ZA201209305B true ZA201209305B (en) 2014-02-26

Family

ID=44168420

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2012/09305A ZA201209305B (en) 2010-05-18 2012-12-07 Method for purifying a fused pyrrolocarbazole derivative

Country Status (20)

Country Link
US (1) US8884014B2 (enExample)
EP (1) EP2571885B1 (enExample)
JP (2) JP5828594B2 (enExample)
KR (1) KR101815332B1 (enExample)
CN (1) CN102958934B (enExample)
AU (1) AU2011256264B2 (enExample)
BR (1) BR112012029374B1 (enExample)
CA (1) CA2799517C (enExample)
CL (1) CL2012003208A1 (enExample)
EA (1) EA021869B1 (enExample)
ES (1) ES2530015T3 (enExample)
IL (2) IL223016A0 (enExample)
MX (1) MX2012013304A (enExample)
MY (1) MY156830A (enExample)
NZ (1) NZ604135A (enExample)
PH (1) PH12012502250A1 (enExample)
SG (2) SG185645A1 (enExample)
UA (1) UA108498C2 (enExample)
WO (1) WO2011146488A1 (enExample)
ZA (1) ZA201209305B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR074374A1 (es) 2008-11-19 2011-01-12 Cephalon Inc Formas de un compuesto de pirrolocarbazol fusionado, composiciones que las comprenden y su uso en el tratamiento de la angiogénesis y los tumores sólidos.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200401316T4 (tr) * 2000-09-29 2004-07-21 Eli Lilly And Company Proliferatif hastalıkları tedavi etmek için yöntemler ve bileşikler
US7169802B2 (en) * 2003-12-23 2007-01-30 Cephalon, Inc. Fused pyrrolocarbazoles
JP2006241579A (ja) 2005-03-07 2006-09-14 Nippon Paint Co Ltd 化成処理剤及び表面処理金属
AR074374A1 (es) 2008-11-19 2011-01-12 Cephalon Inc Formas de un compuesto de pirrolocarbazol fusionado, composiciones que las comprenden y su uso en el tratamiento de la angiogénesis y los tumores sólidos.

Also Published As

Publication number Publication date
SG10201503541WA (en) 2015-06-29
BR112012029374A2 (pt) 2016-07-26
US20130123499A1 (en) 2013-05-16
KR101815332B1 (ko) 2018-01-04
AU2011256264A1 (en) 2013-01-10
WO2011146488A1 (en) 2011-11-24
IL242221B (en) 2018-06-28
IL242221A0 (en) 2015-11-30
US8884014B2 (en) 2014-11-11
CA2799517A1 (en) 2011-11-24
BR112012029374A8 (pt) 2017-12-26
CL2012003208A1 (es) 2013-05-17
ES2530015T3 (es) 2015-02-25
KR20140095116A (ko) 2014-08-01
CN102958934B (zh) 2015-06-17
SG185645A1 (en) 2012-12-28
MX2012013304A (es) 2013-04-03
IL223016A0 (en) 2013-02-03
BR112012029374B1 (pt) 2021-05-25
PH12012502250A1 (en) 2013-02-04
JP2016074668A (ja) 2016-05-12
AU2011256264B2 (en) 2016-09-15
EA201291269A1 (ru) 2013-05-30
CN102958934A (zh) 2013-03-06
NZ604135A (en) 2015-02-27
CA2799517C (en) 2019-01-22
UA108498C2 (en) 2015-05-12
EP2571885B1 (en) 2014-11-12
EP2571885A1 (en) 2013-03-27
HK1182100A1 (en) 2013-11-22
EA021869B1 (ru) 2015-09-30
JP5828594B2 (ja) 2015-12-09
JP2013526573A (ja) 2013-06-24
MY156830A (en) 2016-03-31

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