PL2649044T3 - Sposób syntezy podstawionych pochodnych aminocykloheksanonu - Google Patents
Sposób syntezy podstawionych pochodnych aminocykloheksanonuInfo
- Publication number
- PL2649044T3 PL2649044T3 PL11802280T PL11802280T PL2649044T3 PL 2649044 T3 PL2649044 T3 PL 2649044T3 PL 11802280 T PL11802280 T PL 11802280T PL 11802280 T PL11802280 T PL 11802280T PL 2649044 T3 PL2649044 T3 PL 2649044T3
- Authority
- PL
- Poland
- Prior art keywords
- synthesising
- derivatives
- aminocyclohexanone derivatives
- substituted aminocyclohexanone
- synthesising substituted
- Prior art date
Links
- KMLPEYHLAKSCGX-UHFFFAOYSA-N 2-aminocyclohexan-1-one Chemical class NC1CCCCC1=O KMLPEYHLAKSCGX-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10015428 | 2010-12-08 | ||
| PCT/EP2011/006142 WO2012076165A1 (en) | 2010-12-08 | 2011-12-07 | Method for synthesising substituted aminocyclohexanone derivatives |
| EP11802280.5A EP2649044B1 (en) | 2010-12-08 | 2011-12-07 | Method for synthesising substituted aminocyclohexanone derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2649044T3 true PL2649044T3 (pl) | 2018-02-28 |
Family
ID=43856244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL11802280T PL2649044T3 (pl) | 2010-12-08 | 2011-12-07 | Sposób syntezy podstawionych pochodnych aminocykloheksanonu |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8658827B2 (pl) |
| EP (1) | EP2649044B1 (pl) |
| CN (1) | CN103339102A (pl) |
| AR (1) | AR084209A1 (pl) |
| CA (1) | CA2820413C (pl) |
| ES (1) | ES2653715T3 (pl) |
| HU (1) | HUE033692T2 (pl) |
| IL (1) | IL226721A (pl) |
| PL (1) | PL2649044T3 (pl) |
| PT (1) | PT2649044T (pl) |
| SI (1) | SI2649044T1 (pl) |
| WO (1) | WO2012076165A1 (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017226830B2 (en) | 2016-02-29 | 2021-06-24 | Grünenthal GmbH | Titration of cebranopadol |
| WO2017215591A1 (en) * | 2016-06-13 | 2017-12-21 | Syneurx International (Taiwan) Corp. | Use of lithium benzoate for treating central nervous system disorders |
| WO2024129782A1 (en) | 2022-12-12 | 2024-06-20 | Park Therapeutics, Inc. | Regimens and compositions useful for alleviating pain |
| KR20250145673A (ko) | 2023-02-15 | 2025-10-13 | 애드뉴리스 테라퓨틱스 인코포레이티드 | 통증 완화에 유용한 요법 및 조성물 |
| WO2026035694A1 (en) | 2024-08-05 | 2026-02-12 | Adneuris Therapeutics, Inc. | Cebranopadol useful for preventing or reducing opioid induced respiratory depression |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10252667A1 (de) | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| WO2005070407A1 (en) | 2004-01-21 | 2005-08-04 | Elan Pharmaceuticals, Inc. | Methods of treatment of amyloidosis using aspartyl-protease inihibitors |
| US7385085B2 (en) | 2004-07-09 | 2008-06-10 | Elan Pharmaceuticals, Inc. | Oxime derivative substituted hydroxyethylamine aspartyl protease inhibitors |
| AU2005265354A1 (en) | 2004-07-09 | 2006-01-26 | Elan Pharmaceuticals, Inc. | Oxime derivative hydroxyethylamine aspartyl-protease inhibitors |
| DE102005013287B3 (de) * | 2005-01-27 | 2006-10-12 | Misselhorn, Jürgen, Dipl.Ing. | Wärmekraftmaschine |
| DE102006033114A1 (de) | 2006-07-18 | 2008-01-24 | Grünenthal GmbH | Spirocyclische Azaindol-Derivate |
| DE102006033109A1 (de) * | 2006-07-18 | 2008-01-31 | Grünenthal GmbH | Substituierte Heteroaryl-Derivate |
| DE102007009235A1 (de) | 2007-02-22 | 2008-09-18 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| DE102007009319A1 (de) | 2007-02-22 | 2008-08-28 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| TW200940523A (en) * | 2008-03-17 | 2009-10-01 | Gruenenthal Gmbh | Substituted sulfonamide derivatives |
| PL2260042T3 (pl) * | 2008-03-27 | 2012-02-29 | Gruenenthal Gmbh | Podstawione spirocykliczne pochodne cykloheksanu |
| DK2257526T3 (da) * | 2008-03-27 | 2012-02-06 | Gruenenthal Gmbh | Spiro(5,5)undecan-derivater |
-
2011
- 2011-12-07 ES ES11802280.5T patent/ES2653715T3/es active Active
- 2011-12-07 PT PT118022805T patent/PT2649044T/pt unknown
- 2011-12-07 PL PL11802280T patent/PL2649044T3/pl unknown
- 2011-12-07 HU HUE11802280A patent/HUE033692T2/en unknown
- 2011-12-07 CN CN2011800585236A patent/CN103339102A/zh active Pending
- 2011-12-07 US US13/313,902 patent/US8658827B2/en active Active
- 2011-12-07 EP EP11802280.5A patent/EP2649044B1/en active Active
- 2011-12-07 AR ARP110104587A patent/AR084209A1/es not_active Application Discontinuation
- 2011-12-07 SI SI201131367T patent/SI2649044T1/en unknown
- 2011-12-07 WO PCT/EP2011/006142 patent/WO2012076165A1/en not_active Ceased
- 2011-12-07 CA CA2820413A patent/CA2820413C/en active Active
-
2013
- 2013-06-04 IL IL226721A patent/IL226721A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CA2820413C (en) | 2019-05-07 |
| US8658827B2 (en) | 2014-02-25 |
| AR084209A1 (es) | 2013-05-02 |
| ES2653715T3 (es) | 2018-02-08 |
| PT2649044T (pt) | 2017-12-07 |
| HUE033692T2 (en) | 2017-12-28 |
| IL226721A (en) | 2016-04-21 |
| EP2649044A1 (en) | 2013-10-16 |
| EP2649044B1 (en) | 2017-09-20 |
| CA2820413A1 (en) | 2012-06-14 |
| SI2649044T1 (en) | 2018-01-31 |
| US20120149914A1 (en) | 2012-06-14 |
| CN103339102A (zh) | 2013-10-02 |
| WO2012076165A1 (en) | 2012-06-14 |
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