PT2649044T - Método para síntese de derivados de aminociclo-hexanona substituídos - Google Patents

Método para síntese de derivados de aminociclo-hexanona substituídos

Info

Publication number
PT2649044T
PT2649044T PT118022805T PT11802280T PT2649044T PT 2649044 T PT2649044 T PT 2649044T PT 118022805 T PT118022805 T PT 118022805T PT 11802280 T PT11802280 T PT 11802280T PT 2649044 T PT2649044 T PT 2649044T
Authority
PT
Portugal
Prior art keywords
synthesising
derivatives
aminocyclohexanone derivatives
substituted aminocyclohexanone
synthesising substituted
Prior art date
Application number
PT118022805T
Other languages
English (en)
Inventor
Griebel Carsten
Prühs Stefan
Mueller Marita
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of PT2649044T publication Critical patent/PT2649044T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C221/00Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • C07D491/107Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • C07D491/113Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
PT118022805T 2010-12-08 2011-12-07 Método para síntese de derivados de aminociclo-hexanona substituídos PT2649044T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10015428 2010-12-08

Publications (1)

Publication Number Publication Date
PT2649044T true PT2649044T (pt) 2017-12-07

Family

ID=43856244

Family Applications (1)

Application Number Title Priority Date Filing Date
PT118022805T PT2649044T (pt) 2010-12-08 2011-12-07 Método para síntese de derivados de aminociclo-hexanona substituídos

Country Status (12)

Country Link
US (1) US8658827B2 (pt)
EP (1) EP2649044B1 (pt)
CN (1) CN103339102A (pt)
AR (1) AR084209A1 (pt)
CA (1) CA2820413C (pt)
ES (1) ES2653715T3 (pt)
HU (1) HUE033692T2 (pt)
IL (1) IL226721A (pt)
PL (1) PL2649044T3 (pt)
PT (1) PT2649044T (pt)
SI (1) SI2649044T1 (pt)
WO (1) WO2012076165A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109562089A (zh) 2016-06-13 2019-04-02 心悦生医股份有限公司 苯甲酸锂用于治疗中枢神经系统疾病的用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10252667A1 (de) 2002-11-11 2004-05-27 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
US20060014790A1 (en) 2004-01-21 2006-01-19 Varghese John Methods of treatment of amyloidosis using spirocyclohexane aspartyl-protease inhibitors
AU2005265354A1 (en) 2004-07-09 2006-01-26 Elan Pharmaceuticals, Inc. Oxime derivative hydroxyethylamine aspartyl-protease inhibitors
US7385085B2 (en) 2004-07-09 2008-06-10 Elan Pharmaceuticals, Inc. Oxime derivative substituted hydroxyethylamine aspartyl protease inhibitors
DE102005013287B3 (de) * 2005-01-27 2006-10-12 Misselhorn, Jürgen, Dipl.Ing. Wärmekraftmaschine
DE102006033109A1 (de) * 2006-07-18 2008-01-31 Grünenthal GmbH Substituierte Heteroaryl-Derivate
DE102006033114A1 (de) 2006-07-18 2008-01-24 Grünenthal GmbH Spirocyclische Azaindol-Derivate
DE102007009235A1 (de) 2007-02-22 2008-09-18 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
DE102007009319A1 (de) 2007-02-22 2008-08-28 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
TW200940523A (en) * 2008-03-17 2009-10-01 Gruenenthal Gmbh Substituted sulfonamide derivatives
MX2010010337A (es) * 2008-03-27 2010-10-07 Gruenenthal Gmbh Derivados de espiro(5.5)undecano.
DK2260042T3 (da) * 2008-03-27 2011-10-31 Gruenenthal Gmbh Substituerede spirocykliske cyklohexan-derivater

Also Published As

Publication number Publication date
WO2012076165A1 (en) 2012-06-14
CN103339102A (zh) 2013-10-02
AR084209A1 (es) 2013-05-02
ES2653715T3 (es) 2018-02-08
CA2820413C (en) 2019-05-07
IL226721A (en) 2016-04-21
HUE033692T2 (en) 2017-12-28
CA2820413A1 (en) 2012-06-14
EP2649044B1 (en) 2017-09-20
US8658827B2 (en) 2014-02-25
SI2649044T1 (en) 2018-01-31
US20120149914A1 (en) 2012-06-14
EP2649044A1 (en) 2013-10-16
PL2649044T3 (pl) 2018-02-28

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PT2649044T (pt) Método para síntese de derivados de aminociclo-hexanona substituídos