ZA201202054B - Fermentive production of isobutanol using highly effective ketol-acid reductoisomerase enzymes - Google Patents
Fermentive production of isobutanol using highly effective ketol-acid reductoisomerase enzymesInfo
- Publication number
- ZA201202054B ZA201202054B ZA2012/02054A ZA201202054A ZA201202054B ZA 201202054 B ZA201202054 B ZA 201202054B ZA 2012/02054 A ZA2012/02054 A ZA 2012/02054A ZA 201202054 A ZA201202054 A ZA 201202054A ZA 201202054 B ZA201202054 B ZA 201202054B
- Authority
- ZA
- South Africa
- Prior art keywords
- ketol
- isobutanol
- highly effective
- acid reductoisomerase
- fermentive production
- Prior art date
Links
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 title 2
- 108010000200 Ketol-acid reductoisomerase Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01008—Glycerol-3-phosphate dehydrogenase (NAD+) (1.1.1.8)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01086—Ketol-acid reductoisomerase (1.1.1.86)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01001—Pyruvate decarboxylase (4.1.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01072—Branched-chain-2-oxoacid decarboxylase (4.1.1.72)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/02—Aldehyde-lyases (4.1.2)
- C12Y401/02009—Phosphoketolase (4.1.2.9)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/01009—Dihydroxy-acid dehydratase (4.2.1.9), i.e. acetohydroxyacid dehydratase
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24684409P | 2009-09-29 | 2009-09-29 | |
| PCT/US2010/050724 WO2011041415A1 (en) | 2009-09-29 | 2010-09-29 | Fermentive production of isobutanol using highly effective ketol-acid reductoisomerase enzymes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201202054B true ZA201202054B (en) | 2014-05-28 |
Family
ID=43242464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2012/02054A ZA201202054B (en) | 2009-09-29 | 2012-03-20 | Fermentive production of isobutanol using highly effective ketol-acid reductoisomerase enzymes |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20110244536A1 (enExample) |
| EP (1) | EP2483411A1 (enExample) |
| JP (1) | JP5805094B2 (enExample) |
| CN (1) | CN102666866A (enExample) |
| AU (1) | AU2010300642B2 (enExample) |
| BR (1) | BR112012007168A2 (enExample) |
| CA (1) | CA2775892A1 (enExample) |
| IN (1) | IN2012DN02227A (enExample) |
| WO (1) | WO2011041415A1 (enExample) |
| ZA (1) | ZA201202054B (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9303225B2 (en) | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| CN101680007A (zh) | 2007-04-18 | 2010-03-24 | 纳幕尔杜邦公司 | 使用高活性酮醇酸还原异构酶来发酵生产异丁醇 |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| BRPI0909989A2 (pt) | 2008-06-05 | 2021-06-22 | Butamax Advanced Biofuels Llc | célula de levedura recombinante e método para a produção de um produto |
| CN102186983A (zh) | 2008-09-29 | 2011-09-14 | 布特马斯先进生物燃料有限责任公司 | 酵母中提高的异源Fe-S酶活性 |
| CN102186973B (zh) * | 2008-09-29 | 2017-08-15 | 布特马斯先进生物燃料有限责任公司 | 细菌的[2Fe‑2S]二羟酸脱水酶的鉴定和用途 |
| US9260708B2 (en) * | 2009-09-29 | 2016-02-16 | Butamax Advanced Biofuels Llc | Yeast production host cells |
| CN102762722B (zh) | 2009-12-29 | 2015-05-20 | 布特马斯先进生物燃料有限责任公司 | 用于发酵生产低级烷基醇的醇脱氢酶(adh) |
| KR20130027063A (ko) | 2010-02-17 | 2013-03-14 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | Ｆｅ-ｓ 클러스터 요구성 단백질의 활성 향상 |
| WO2011151326A2 (en) | 2010-05-31 | 2011-12-08 | Vib Vzw | The use of transporters to modulate flavor production by yeast |
| CA2801576A1 (en) | 2010-06-17 | 2011-12-22 | Butamax(Tm) Advanced Biofuels Llc | Yeast production culture for the production of butanol |
| US9012190B2 (en) | 2011-06-15 | 2015-04-21 | Butamax Advanced Biofuels Llc | Use of thiamine and nicotine adenine dinucleotide for butanol production |
| HUE044304T2 (hu) | 2010-06-18 | 2019-10-28 | Butamax Tm Advanced Biofuels | Olajból nyert oldószerek kivonása alkoholeltávolításra extraháló fermentációban |
| US9040263B2 (en) | 2010-07-28 | 2015-05-26 | Butamax Advanced Biofuels Llc | Production of alcohol esters and in situ product removal during alcohol fermentation |
| US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
| BR112013005386A2 (pt) | 2010-09-07 | 2016-06-07 | Butamax Advanced Biofuels Llc | célula hospedeira recombinante, método, composição e uso de uma célula hospedeira |
| US8765425B2 (en) | 2011-03-23 | 2014-07-01 | Butamax Advanced Biofuels Llc | In situ expression of lipase for enzymatic production of alcohol esters during fermentation |
| US8759044B2 (en) | 2011-03-23 | 2014-06-24 | Butamax Advanced Biofuels Llc | In situ expression of lipase for enzymatic production of alcohol esters during fermentation |
| KR20140092759A (ko) | 2011-03-24 | 2014-07-24 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 숙주 세포 및 아이소부탄올의 제조 방법 |
| AU2012249389A1 (en) | 2011-04-29 | 2013-11-14 | Danisco Us Inc. | Production of mevalonate, isoprene, and isoprenoids using genes encoding polypeptides having thiolase, HMG-CoA synthase and HMG-CoA reductase enzymatic activities |
| BR112013032319A2 (pt) | 2011-06-17 | 2016-12-20 | Butamax Advanced Biofuels Llc | métodos da geração de coprodutos de destilação, coprodutos de destilação, método para atenuar o impacto de contaminantes de fermentação, método para a redução da contaminação por micotoxinas, método para a redução da variabilidade do teor de lipídeos, método para aumento do teor de triglicerídeos, método de produção de um coproduto de destilação para o combustível e método de produção de um coproduto destilação para o biodiesel |
| BR112014001943A2 (pt) | 2011-07-28 | 2018-08-07 | Butamax Advanced Biofuels Llc | método de converter alfa-cetoisovalerato a isobutiraldeído e método de produção de isobutanol |
| WO2013086222A2 (en) | 2011-12-09 | 2013-06-13 | Butamax(Tm) Advanced Biofuels Llc | Process to remove product alcohols from fermentation broth |
| EP2798072A2 (en) | 2011-12-30 | 2014-11-05 | Butamax Advanced Biofuels LLC | Fermentative production of alcohols |
| WO2013142338A1 (en) | 2012-03-23 | 2013-09-26 | Butamax(Tm) Advanced Biofuels Llc | Acetate supplemention of medium for butanologens |
| JP6321631B2 (ja) | 2012-05-11 | 2018-05-09 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | ケトール酸レダクトイソメラーゼ酵素及び使用方法 |
| US20140024064A1 (en) | 2012-07-23 | 2014-01-23 | Butamax(Tm) Advanced Biofuels Llc | Processes and systems for the production of fermentative alcohols |
| WO2014031831A1 (en) | 2012-08-22 | 2014-02-27 | Butamax Advanced Biofuels Llc | Production of fermentation products |
| BR112015005439A8 (pt) | 2012-09-12 | 2022-01-11 | Butamax Advanced Biofuels Llc | Método para recuperar um produto alcoólico de um caldo de fermentação e sistema |
| WO2014047421A1 (en) | 2012-09-21 | 2014-03-27 | Butamax(Tm) Advanced Biofuels Llc | Production of renewable hydrocarbon compositions |
| CA2886157A1 (en) * | 2012-09-26 | 2014-04-03 | Butamax Advanced Biofuels Llc | Polypeptides with ketol-acid reductoisomerase activity |
| CA2884876A1 (en) | 2012-09-28 | 2014-04-03 | Butamax Advanced Biofuels Llc | Production of fermentation products |
| US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
| BR112015008077A2 (pt) | 2012-10-11 | 2017-12-05 | Butamax Advanced Biofuels Llc | métodos para a produção de um produto de fermentação |
| US9650624B2 (en) | 2012-12-28 | 2017-05-16 | Butamax Advanced Biofuels Llc | DHAD variants for butanol production |
| WO2014105840A1 (en) | 2012-12-31 | 2014-07-03 | Butamax Advanced Biofuels Llc | Fermentative production of alcohols |
| WO2014159309A1 (en) | 2013-03-12 | 2014-10-02 | Butamax Advanced Biofuels Llc | Processes and systems for the production of alcohols |
| US10006033B2 (en) * | 2013-03-14 | 2018-06-26 | The Regents Of The University Of California | Recombinant microorganisms having a methanol elongation cycle (MEC) |
| ES2735024T3 (es) | 2013-03-14 | 2019-12-13 | Du Pont | Glicerol-3-fosfato deshidrogenasa para la producción de butanol |
| BR112015020685A2 (pt) | 2013-03-15 | 2017-07-18 | Butamax Advanced Biofuels Llc | método para a recuperação do butanol, composição, métodos para a extração de álcool e de secagem |
| US9771602B2 (en) | 2013-03-15 | 2017-09-26 | Butamax Advanced Biofuels Llc | Competitive growth and/or production advantage for butanologen microorganism |
| WO2014144643A1 (en) | 2013-03-15 | 2014-09-18 | Butamax Advanced Biofuels Llc | Method for producing butanol using extractive fermentation |
| WO2014151645A1 (en) | 2013-03-15 | 2014-09-25 | Butamax Advanced Biofuels Llc | Process for maximizing biomass growth and butanol yield by feedback control |
| US9580705B2 (en) | 2013-03-15 | 2017-02-28 | Butamax Advanced Biofuels Llc | DHAD variants and methods of screening |
| US9663759B2 (en) | 2013-07-03 | 2017-05-30 | Butamax Advanced Biofuels Llc | Partial adaptation for butanol production |
| US10280438B2 (en) | 2014-08-11 | 2019-05-07 | Butamax Advanced Biofuels Llc | Method for the production of yeast |
| US11680280B2 (en) | 2018-01-09 | 2023-06-20 | Lygos, Inc. | Recombinant host cells and methods for the production of isobutyric acid |
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|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| FR2696190B1 (fr) * | 1992-09-25 | 1994-12-09 | Agronomique Inst Nat Rech | Acide nucléique codant pour une alpha-acétolactate synthase et ses applications. |
| FR2829363B1 (fr) * | 2001-09-10 | 2005-11-04 | Aventis Cropscience Sa | Utilisations d'inhibiteurs de l'acetohydroxyacide isomeroreductase pour le traitement des maladies fongiques des cultures |
| CN101160405B (zh) | 2005-04-12 | 2014-01-01 | 纳幕尔杜邦公司 | 处理生物质以获得目标化学物质 |
| JP5276986B2 (ja) * | 2005-10-26 | 2013-08-28 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 四炭素アルコールの発酵性生産 |
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| CN101680007A (zh) * | 2007-04-18 | 2010-03-24 | 纳幕尔杜邦公司 | 使用高活性酮醇酸还原异构酶来发酵生产异丁醇 |
| WO2009085953A2 (en) | 2007-12-20 | 2009-07-09 | E. I. Du Pont De Nemours And Company | Ketol-acid reductoisomerase using nadh |
| US8372612B2 (en) * | 2007-12-21 | 2013-02-12 | Butamax(Tm) Advanced Biofuels Llc | Production of four carbon alcohols using improved strain |
| US8518678B2 (en) * | 2007-12-21 | 2013-08-27 | Butamax(Tm) Advanced Biofuels Llc | Strain comprising increased expression of a CFA coding region for butanol production |
| CA2710359C (en) * | 2007-12-23 | 2018-02-20 | Gevo, Inc. | Yeast organism producing isobutanol at a high yield |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| BRPI0909989A2 (pt) | 2008-06-05 | 2021-06-22 | Butamax Advanced Biofuels Llc | célula de levedura recombinante e método para a produção de um produto |
| CN102186983A (zh) | 2008-09-29 | 2011-09-14 | 布特马斯先进生物燃料有限责任公司 | 酵母中提高的异源Fe-S酶活性 |
| CN102186973B (zh) | 2008-09-29 | 2017-08-15 | 布特马斯先进生物燃料有限责任公司 | 细菌的[2Fe‑2S]二羟酸脱水酶的鉴定和用途 |
| CA2736420A1 (en) * | 2008-09-29 | 2010-04-01 | Butamaxtm Advanced Biofuels Llc | Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria |
| BRPI0913547A2 (pt) | 2008-09-29 | 2020-08-18 | Butamax Advanced Biofuels Llc | célula bacteriana ácido-lática recombinante, método para a produção de 2-butanol e método para a produção de 2-butanona |
| WO2010037119A1 (en) | 2008-09-29 | 2010-04-01 | Butamax™ Advanced Biofuels LLC | Enhanced iron-sulfur cluster formation for increased dihydroxy-acid dehydratase activity in lactic acid bacteria |
| AU2009320163B2 (en) | 2008-10-27 | 2014-10-02 | Butamax(Tm) Advanced Biofuels Llc | Carbon pathway optimized production hosts for the production of isobutanol |
| US8465964B2 (en) | 2008-11-13 | 2013-06-18 | Butamax (TM) Advanced Biofules LLC | Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis |
| ES2773130T3 (es) | 2014-06-18 | 2020-07-09 | Fotona D O O | Cabeza de tratamiento láser y sistema láser |
-
2010
- 2010-09-29 IN IN2227DEN2012 patent/IN2012DN02227A/en unknown
- 2010-09-29 CA CA2775892A patent/CA2775892A1/en not_active Abandoned
- 2010-09-29 AU AU2010300642A patent/AU2010300642B2/en not_active Ceased
- 2010-09-29 WO PCT/US2010/050724 patent/WO2011041415A1/en not_active Ceased
- 2010-09-29 JP JP2012532274A patent/JP5805094B2/ja not_active Expired - Fee Related
- 2010-09-29 EP EP10760891A patent/EP2483411A1/en not_active Withdrawn
- 2010-09-29 BR BR112012007168A patent/BR112012007168A2/pt not_active IP Right Cessation
- 2010-09-29 CN CN2010800522425A patent/CN102666866A/zh active Pending
- 2010-09-29 US US12/893,077 patent/US20110244536A1/en not_active Abandoned
-
2012
- 2012-03-20 ZA ZA2012/02054A patent/ZA201202054B/en unknown
-
2016
- 2016-07-14 US US15/209,841 patent/US20160319307A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2483411A1 (en) | 2012-08-08 |
| IN2012DN02227A (enExample) | 2015-08-21 |
| CA2775892A1 (en) | 2011-04-07 |
| JP5805094B2 (ja) | 2015-11-04 |
| AU2010300642A1 (en) | 2012-04-05 |
| US20160319307A1 (en) | 2016-11-03 |
| CN102666866A (zh) | 2012-09-12 |
| BR112012007168A2 (pt) | 2019-09-24 |
| US20110244536A1 (en) | 2011-10-06 |
| JP2013505740A (ja) | 2013-02-21 |
| AU2010300642B2 (en) | 2015-05-14 |
| WO2011041415A1 (en) | 2011-04-07 |
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