ZA201101097B - Pharmaceutical composition of n-[2,4-bis (1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide and administration thereof - Google Patents

Pharmaceutical composition of n-[2,4-bis (1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide and administration thereof

Info

Publication number
ZA201101097B
ZA201101097B ZA2011/01097A ZA201101097A ZA201101097B ZA 201101097 B ZA201101097 B ZA 201101097B ZA 2011/01097 A ZA2011/01097 A ZA 2011/01097A ZA 201101097 A ZA201101097 A ZA 201101097A ZA 201101097 B ZA201101097 B ZA 201101097B
Authority
ZA
South Africa
Prior art keywords
oxoquinoline
dimethylethyl
carboxamide
hydroxyphenyl
dihydro
Prior art date
Application number
ZA2011/01097A
Other languages
English (en)
Inventor
William Rowe
Patricia Hurter
Christopher Young
Kirk Dinehart
Marinus Jacobus Verwijs
Kirk Overhoff
Peter D J Grootenhuis
Martyn C Botfield
Alfredo Grossi
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41206223&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA201101097(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of ZA201101097B publication Critical patent/ZA201101097B/en

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
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    • A61K9/2022—Organic macromolecular compounds
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ZA2011/01097A 2008-08-13 2011-02-10 Pharmaceutical composition of n-[2,4-bis (1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide and administration thereof ZA201101097B (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US8870408P 2008-08-13 2008-08-13
US8880108P 2008-08-14 2008-08-14
US9009608P 2008-08-19 2008-08-19
US14616309P 2009-01-21 2009-01-21
US18152709P 2009-05-27 2009-05-27
US18334509P 2009-06-02 2009-06-02
PCT/US2009/004629 WO2010019239A2 (en) 2008-08-13 2009-08-13 Pharmaceutical composition and administrations thereof

Publications (1)

Publication Number Publication Date
ZA201101097B true ZA201101097B (en) 2012-05-30

Family

ID=41206223

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2011/01097A ZA201101097B (en) 2008-08-13 2011-02-10 Pharmaceutical composition of n-[2,4-bis (1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide and administration thereof

Country Status (27)

Country Link
US (1) US20120220625A1 (enExample)
EP (3) EP3842037A1 (enExample)
JP (2) JP5575768B2 (enExample)
KR (5) KR20240066199A (enExample)
CN (1) CN102231990B (enExample)
AU (2) AU2009282419B2 (enExample)
BR (1) BRPI0916877A2 (enExample)
CA (1) CA2733908C (enExample)
CY (2) CY1119945T1 (enExample)
DK (2) DK3345625T3 (enExample)
EA (1) EA021706B1 (enExample)
ES (2) ES2660143T3 (enExample)
HR (2) HRP20180328T1 (enExample)
HU (2) HUE035931T2 (enExample)
IL (3) IL211203A (enExample)
LT (2) LT2328618T (enExample)
ME (1) ME03019B (enExample)
MX (3) MX366161B (enExample)
NO (1) NO2328618T3 (enExample)
NZ (1) NZ591535A (enExample)
PL (2) PL3345625T3 (enExample)
PT (2) PT2328618T (enExample)
RS (2) RS61408B1 (enExample)
SI (2) SI3345625T1 (enExample)
SM (2) SMT201800074T1 (enExample)
WO (1) WO2010019239A2 (enExample)
ZA (1) ZA201101097B (enExample)

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CN1898221A (zh) 2003-09-06 2007-01-17 沃泰克斯药物股份有限公司 Atp－结合弹夹转运蛋白的调控剂
US7977322B2 (en) 2004-08-20 2011-07-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
HUE032540T2 (en) 2004-06-24 2017-09-28 Vertex Pharma Modulators of ATP-binding cassette transporters
ATE512145T1 (de) 2005-08-11 2011-06-15 Vertex Pharma Modulatoren des cystic fibrosis transmembrane conductance regulators
EP2395002B1 (en) 2005-11-08 2014-06-18 Vertex Pharmaceuticals Inc. Pharmaceutical composition containing a heterocyclic modulator of atp-binding cassette transporters.
CN101395147B (zh) 2005-12-28 2013-05-29 弗特克斯药品有限公司 作为atp-结合盒转运蛋白调节剂用于治疗囊性纤维化的1-(苯并[d][1,3]间二氧杂环戊烯-5-基)-n-(苯基)环丙烷-甲酰胺衍生物及相关化合物
CA2635581C (en) 2005-12-28 2017-02-28 Vertex Pharmaceuticals Incorporated Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
US7645789B2 (en) 2006-04-07 2010-01-12 Vertex Pharmaceuticals Incorporated Indole derivatives as CFTR modulators
USRE50453E1 (en) 2006-04-07 2025-06-10 Vertex Pharmaceuticals Incorporated Indole derivatives as CFTR modulators
US10022352B2 (en) 2006-04-07 2018-07-17 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
PT2674428T (pt) 2006-04-07 2016-07-14 Vertex Pharma Modeladores de transportadores de cassetes de ligação de atp
US8563573B2 (en) 2007-11-02 2013-10-22 Vertex Pharmaceuticals Incorporated Azaindole derivatives as CFTR modulators
NZ581259A (en) 2007-05-09 2012-07-27 Vertex Pharma Modulators of cystic fibrosis transmembrane conductance regulator
HUE028426T2 (en) 2007-08-24 2016-12-28 Vertex Pharma Isothiazolopyridinones for (inter alia) treating cystic fibrosis
ES2556080T3 (es) 2007-11-16 2016-01-12 Vertex Pharmaceuticals Incorporated Moduladores de isoquinolina de transportadores de casete de unión a ATP
UA102534C2 (xx) 2007-12-07 2013-07-25 Вертекс Фармасьютикалз Инкорпорейтед ТВЕРДА ФОРМА 3-(6-(1-(2,2-ДИФТОРБЕНЗО$d]$1,3]-ДІОКСОЛ-5-ІЛ)-ЦИКЛОПРОПАНКАРБОКСАМІДО)-3-МЕТИЛПІРИДИН-2-ІЛ)БЕНЗОЙНОЇ КИСЛОТИ (ВАРІАНТИ)$ТВЕРДАЯ ФОРМА 3-(6-(1-(2,2-ДИФТОРБЕНЗО$d]$1,3]-ДИОКСОЛ-5-ИЛ)-ЦИКЛОПРОПАНКАРБОКСАМИДО)-3-МЕТИЛПИРИДИН-2-ИЛ)БЕНЗОЙНОЙ КИСЛОТЫ (ВАРИАНТЫ)
UA95199C2 (en) * 2007-12-07 2011-07-11 Вертекс Фармасьютикалз Инкорпорейтед Aqueous formulation of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
US20100036130A1 (en) 2007-12-07 2010-02-11 Vertex Pharmaceuticals Incorporated Processes for producing cycloalkylcarboxamido-pyridine benzoic acids
LT2639223T (lt) 2007-12-07 2017-06-26 Vertex Pharmaceuticals Incorporated Cikloalkilkarboksiamido-piridino benzenkarboksirūgščių gamybos būdas
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