PL2328618T3 - Kompozycja farmaceutyczna n-[2,4-bis(1,1-dimetyloetylo)5-hydroksyfenylo]-1,4-dihydro-4-oksochinolino-3-karboksyamidu i jej podawanie - Google Patents
Kompozycja farmaceutyczna n-[2,4-bis(1,1-dimetyloetylo)5-hydroksyfenylo]-1,4-dihydro-4-oksochinolino-3-karboksyamidu i jej podawanieInfo
- Publication number
- PL2328618T3 PL2328618T3 PL09789125T PL09789125T PL2328618T3 PL 2328618 T3 PL2328618 T3 PL 2328618T3 PL 09789125 T PL09789125 T PL 09789125T PL 09789125 T PL09789125 T PL 09789125T PL 2328618 T3 PL2328618 T3 PL 2328618T3
- Authority
- PL
- Poland
- Prior art keywords
- oxoquinoline
- dimethylethyl
- carboxamide
- hydroxyphenyl
- dihydro
- Prior art date
Links
- PURKAOJPTOLRMP-UHFFFAOYSA-N ivacaftor Chemical group C1=C(O)C(C(C)(C)C)=CC(C(C)(C)C)=C1NC(=O)C1=CNC2=CC=CC=C2C1=O PURKAOJPTOLRMP-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Organic Chemistry (AREA)
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- Epidemiology (AREA)
- Pulmonology (AREA)
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- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
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Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8870408P | 2008-08-13 | 2008-08-13 | |
| US8880108P | 2008-08-14 | 2008-08-14 | |
| US9009608P | 2008-08-19 | 2008-08-19 | |
| US14616309P | 2009-01-21 | 2009-01-21 | |
| US18152709P | 2009-05-27 | 2009-05-27 | |
| US18334509P | 2009-06-02 | 2009-06-02 | |
| PCT/US2009/004629 WO2010019239A2 (en) | 2008-08-13 | 2009-08-13 | Pharmaceutical composition and administrations thereof |
| EP09789125.3A EP2328618B1 (en) | 2008-08-13 | 2009-08-13 | Pharmaceutical composition of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4- oxoquinoline-3-carboxamide and administration thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2328618T3 true PL2328618T3 (pl) | 2018-06-29 |
Family
ID=41206223
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09789125T PL2328618T3 (pl) | 2008-08-13 | 2009-08-13 | Kompozycja farmaceutyczna n-[2,4-bis(1,1-dimetyloetylo)5-hydroksyfenylo]-1,4-dihydro-4-oksochinolino-3-karboksyamidu i jej podawanie |
| PL17204189T PL3345625T3 (pl) | 2008-08-13 | 2009-08-13 | Kompozycja farmaceutyczna i jej podawania |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17204189T PL3345625T3 (pl) | 2008-08-13 | 2009-08-13 | Kompozycja farmaceutyczna i jej podawania |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US20120220625A1 (enExample) |
| EP (3) | EP3345625B1 (enExample) |
| JP (2) | JP5575768B2 (enExample) |
| KR (5) | KR20220057663A (enExample) |
| CN (1) | CN102231990B (enExample) |
| AU (2) | AU2009282419B2 (enExample) |
| BR (1) | BRPI0916877A2 (enExample) |
| CA (1) | CA2733908C (enExample) |
| CY (2) | CY1119945T1 (enExample) |
| DK (2) | DK3345625T3 (enExample) |
| EA (1) | EA021706B1 (enExample) |
| ES (2) | ES2857152T3 (enExample) |
| HR (2) | HRP20180328T1 (enExample) |
| HU (2) | HUE035931T2 (enExample) |
| IL (3) | IL211203A (enExample) |
| LT (2) | LT3345625T (enExample) |
| ME (1) | ME03019B (enExample) |
| MX (3) | MX373230B (enExample) |
| NO (1) | NO2328618T3 (enExample) |
| NZ (1) | NZ591535A (enExample) |
| PL (2) | PL2328618T3 (enExample) |
| PT (2) | PT3345625T (enExample) |
| RS (2) | RS56894B1 (enExample) |
| SI (2) | SI2328618T1 (enExample) |
| SM (2) | SMT201800074T1 (enExample) |
| WO (1) | WO2010019239A2 (enExample) |
| ZA (1) | ZA201101097B (enExample) |
Families Citing this family (118)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1898221A (zh) | 2003-09-06 | 2007-01-17 | 沃泰克斯药物股份有限公司 | Atp-结合弹夹转运蛋白的调控剂 |
| US7977322B2 (en) | 2004-08-20 | 2011-07-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
| PT1773816E (pt) | 2004-06-24 | 2015-04-29 | Vertex Pharma | Moduladores de transportadores de cassete de ligação de atp |
| CA2618057A1 (en) | 2005-08-11 | 2007-02-22 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
| CN102775396B (zh) | 2005-11-08 | 2014-10-08 | 沃泰克斯药物股份有限公司 | Atp-结合弹夹转运蛋白的杂环调控剂 |
| US7691902B2 (en) | 2005-12-28 | 2010-04-06 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
| RS55940B1 (sr) | 2005-12-28 | 2017-09-29 | Vertex Pharma | Čvrsti oblici n-[2,4-bis(1,1-dimetiletil)-5-hidroksifenil]-1,4-dihidro-4-oksohinolin-3-karboksamida |
| USRE50453E1 (en) | 2006-04-07 | 2025-06-10 | Vertex Pharmaceuticals Incorporated | Indole derivatives as CFTR modulators |
| US7645789B2 (en) * | 2006-04-07 | 2010-01-12 | Vertex Pharmaceuticals Incorporated | Indole derivatives as CFTR modulators |
| PL2007756T3 (pl) | 2006-04-07 | 2016-01-29 | Vertex Pharma | Modulatory transporterów posiadających kasetę wiążącą ATP |
| US10022352B2 (en) | 2006-04-07 | 2018-07-17 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
| US8563573B2 (en) | 2007-11-02 | 2013-10-22 | Vertex Pharmaceuticals Incorporated | Azaindole derivatives as CFTR modulators |
| JP5497633B2 (ja) | 2007-05-09 | 2014-05-21 | バーテックス ファーマシューティカルズ インコーポレイテッド | Cftrのモジュレーター |
| AU2008302598B2 (en) | 2007-08-24 | 2014-07-17 | Vertex Pharmaceuticals Incorporated | Isothiazolopyridinones useful for the treatment of (inter alia) Cystic Fibrosis |
| CN101952254B (zh) | 2007-11-16 | 2012-09-05 | 沃泰克斯药物股份有限公司 | Atp结合盒转运蛋白的异喹啉调节剂 |
| EP2231606B1 (en) | 2007-12-07 | 2013-02-13 | Vertex Pharmaceuticals Incorporated | Processes for producing cycloalkylcarboxiamido-pyridine benzoic acids |
| EA201070699A1 (ru) * | 2007-12-07 | 2011-02-28 | Вертекс Фармасьютикалз Инкорпорейтед | Композиции 3-(6-(1-2,2-дифторбензо[d][1,3]диоксол-5-ил)циклопропанкарбоксамидо)-3-метилпиридин-2-ил)бензойной кислоты |
| NZ614151A (en) | 2007-12-07 | 2015-04-24 | Vertex Pharma | Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid |
| US20100036130A1 (en) | 2007-12-07 | 2010-02-11 | Vertex Pharmaceuticals Incorporated | Processes for producing cycloalkylcarboxamido-pyridine benzoic acids |
| ES2647531T3 (es) | 2008-02-28 | 2017-12-22 | Vertex Pharmaceuticals Incorporated | Derivados de heteroarilo como moduladores de CFTR |
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| US20100074949A1 (en) * | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
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