ZA201008024B - Anti-flt3 antibodies - Google Patents

Anti-flt3 antibodies

Info

Publication number
ZA201008024B
ZA201008024B ZA2010/08024A ZA201008024A ZA201008024B ZA 201008024 B ZA201008024 B ZA 201008024B ZA 2010/08024 A ZA2010/08024 A ZA 2010/08024A ZA 201008024 A ZA201008024 A ZA 201008024A ZA 201008024 B ZA201008024 B ZA 201008024B
Authority
ZA
South Africa
Prior art keywords
flt3 antibodies
flt3
antibodies
Prior art date
Application number
ZA2010/08024A
Other languages
English (en)
Inventor
Yiwen Li
Dan Lu
David Surguladze
James R Tonra
Original Assignee
Imclone Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41092183&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA201008024(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Imclone Llc filed Critical Imclone Llc
Publication of ZA201008024B publication Critical patent/ZA201008024B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
ZA2010/08024A 2008-05-30 2010-11-09 Anti-flt3 antibodies ZA201008024B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US13039408P 2008-05-30 2008-05-30
US13053908P 2008-05-30 2008-05-30
US13039508P 2008-05-30 2008-05-30
PCT/US2009/045365 WO2009155015A1 (en) 2008-05-30 2009-05-28 Anti-flt3 antibodies

Publications (1)

Publication Number Publication Date
ZA201008024B true ZA201008024B (en) 2012-04-25

Family

ID=41092183

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2010/08024A ZA201008024B (en) 2008-05-30 2010-11-09 Anti-flt3 antibodies

Country Status (18)

Country Link
US (3) US20090297529A1 (https=)
EP (1) EP2300500A1 (https=)
JP (1) JP2011521647A (https=)
KR (1) KR20110004455A (https=)
CN (1) CN102046659A (https=)
AR (1) AR071891A1 (https=)
AU (1) AU2009260517B2 (https=)
BR (1) BRPI0912173A2 (https=)
CA (1) CA2726522A1 (https=)
CL (1) CL2009001277A1 (https=)
EA (1) EA201071421A1 (https=)
IL (1) IL209142A0 (https=)
MX (1) MX2010013144A (https=)
NZ (1) NZ588791A (https=)
PE (1) PE20091963A1 (https=)
TW (1) TWI374032B (https=)
WO (1) WO2009155015A1 (https=)
ZA (1) ZA201008024B (https=)

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Also Published As

Publication number Publication date
CN102046659A (zh) 2011-05-04
TWI374032B (en) 2012-10-11
US20090297529A1 (en) 2009-12-03
EA201071421A1 (ru) 2011-08-30
PE20091963A1 (es) 2010-01-15
AU2009260517B2 (en) 2012-12-06
MX2010013144A (es) 2010-12-21
EP2300500A1 (en) 2011-03-30
US8071099B2 (en) 2011-12-06
CA2726522A1 (en) 2009-12-23
WO2009155015A1 (en) 2009-12-23
US20110091470A1 (en) 2011-04-21
JP2011521647A (ja) 2011-07-28
BRPI0912173A2 (pt) 2016-07-26
TW201010722A (en) 2010-03-16
IL209142A0 (en) 2011-01-31
NZ588791A (en) 2012-05-25
AR071891A1 (es) 2010-07-21
CL2009001277A1 (es) 2010-10-08
AU2009260517A1 (en) 2009-12-23
KR20110004455A (ko) 2011-01-13
US20110008355A1 (en) 2011-01-13

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