ZA201005780B - Certain chemical entities,compositions and methods - Google Patents

Certain chemical entities,compositions and methods

Info

Publication number
ZA201005780B
ZA201005780B ZA2010/05780A ZA201005780A ZA201005780B ZA 201005780 B ZA201005780 B ZA 201005780B ZA 2010/05780 A ZA2010/05780 A ZA 2010/05780A ZA 201005780 A ZA201005780 A ZA 201005780A ZA 201005780 B ZA201005780 B ZA 201005780B
Authority
ZA
South Africa
Prior art keywords
compositions
methods
chemical entities
certain chemical
certain
Prior art date
Application number
ZA2010/05780A
Other languages
English (en)
Inventor
Brian Stoltz
Jeff Gardina
Scott Collibee
Zhe Yang
Alex Muci
Bradley P Morgan
Luke W Ashcraft
Jianchao Wang
Gustave Bergnes
Original Assignee
Cytokinetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytokinetics Inc filed Critical Cytokinetics Inc
Publication of ZA201005780B publication Critical patent/ZA201005780B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
  • Medicinal Preparation (AREA)
ZA2010/05780A 2008-02-04 2010-08-13 Certain chemical entities,compositions and methods ZA201005780B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2606708P 2008-02-04 2008-02-04
PCT/US2009/000686 WO2009099594A1 (en) 2008-02-04 2009-02-02 Certain chemical entities, compositions and methods

Publications (1)

Publication Number Publication Date
ZA201005780B true ZA201005780B (en) 2011-04-28

Family

ID=40952391

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2010/05780A ZA201005780B (en) 2008-02-04 2010-08-13 Certain chemical entities,compositions and methods

Country Status (18)

Country Link
US (2) US7989469B2 (enExample)
EP (1) EP2244711A4 (enExample)
JP (1) JP2011510985A (enExample)
KR (1) KR20100119773A (enExample)
CN (1) CN101983061A (enExample)
AR (1) AR072242A1 (enExample)
AU (1) AU2009210787A1 (enExample)
BR (1) BRPI0907502A2 (enExample)
CA (1) CA2713864A1 (enExample)
CL (1) CL2009000246A1 (enExample)
CO (1) CO6290673A2 (enExample)
EA (1) EA201001224A1 (enExample)
EC (2) ECSP10010430A (enExample)
IL (1) IL207367A0 (enExample)
MX (1) MX2010008518A (enExample)
TW (1) TW200946524A (enExample)
WO (1) WO2009099594A1 (enExample)
ZA (1) ZA201005780B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8299248B2 (en) 2006-08-02 2012-10-30 Cytokinetics, Incorporated Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
CA2713864A1 (en) * 2008-02-04 2009-08-13 Cytokinetics, Incorporated Certain chemical entities, compositions and methods
CN102127070A (zh) * 2010-01-15 2011-07-20 山东轩竹医药科技有限公司 吡啶并环衍生物
WO2013007167A1 (zh) * 2011-07-09 2013-01-17 山东轩竹医药科技有限公司 二肽基肽酶-iv抑制剂的盐的晶型i及其制备方法和应用
EA028060B1 (ru) 2011-07-13 2017-10-31 Сайтокинетикс, Инк. Комбинированная терапия бокового амиотрофического склероза
KR102163931B1 (ko) * 2012-04-11 2020-10-12 싸이토키네틱스, 인코포레이티드 골격근 피로에 대한 저항을 개선
PT3137622T (pt) 2014-04-29 2022-03-08 Cytokinetics Inc Métodos para reduzir o declínio da capacidade vital
TW201927738A (zh) * 2017-12-14 2019-07-16 丹麥商Ｎｍｄ藥品公司 用於治療神經肌肉病症的化合物
TWI794369B (zh) * 2017-12-14 2023-03-01 丹麥商Ｎｍｄ藥品公司 用於治療神經肌肉病症的化合物
BR112021023635A2 (pt) 2019-05-28 2022-02-01 Mankind Pharma Ltd Novos compostos para inibição de janus quinase 1
CA3213703A1 (en) * 2021-05-06 2022-11-10 Peter Ray Pkc-theta modulators
CN118702622A (zh) * 2024-08-30 2024-09-27 阜新达得利化工股份有限公司 一种3-溴-2-氰基吡啶的制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0206860D0 (en) 2002-03-22 2002-05-01 Glaxo Group Ltd Compounds
GB0212048D0 (en) 2002-05-24 2002-07-03 Merck Sharp & Dohme Therapeutic agents
AU2003294249A1 (en) 2002-11-08 2004-06-03 Trimeris, Inc. Hetero-substituted benzimidazole compounds and antiviral uses thereof
CA2530081A1 (en) 2003-07-01 2005-01-13 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
EP1694323A4 (en) 2003-12-19 2009-05-13 Elixir Pharmaceuticals Inc METHOD FOR TREATING A DISEASE
JP2007529422A (ja) 2004-01-29 2007-10-25 エリクシアー ファーマシューティカルズ， インコーポレイテッド 抗ウイルス治療
WO2005108374A1 (en) 2004-04-29 2005-11-17 Fmc Corporation Insecticidal diazole and triazole derivatives
GB0420719D0 (en) 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
EP1959962A2 (en) * 2005-12-16 2008-08-27 Cytokinetics, Inc. Certain chemical entities, compositions, and methods
US8227603B2 (en) 2006-08-01 2012-07-24 Cytokinetics, Inc. Modulating skeletal muscle
RS54542B1 (sr) 2006-08-02 2016-06-30 Cytokinetics, Inc. Određeni hemijski entiteti, kompozicije i metodi koji obuhvataju imidazopirimidine
EP2457913B1 (en) 2006-10-19 2017-04-19 Signal Pharmaceuticals, LLC Heteroaryl compounds, compositions thereof, and methods of treatment therewith
CL2007002994A1 (es) 2006-10-19 2008-02-08 Wyeth Corp Compuestos derivados heterociclicos que contienen sulfamoilo, inhibidores de hsp90; composicion farmaceutica; y uso para el tratamiento del cancer, tal como cancer de mama, de colon y prostata, entre otros.
WO2008075007A1 (en) * 2006-12-21 2008-06-26 Cancer Research Technology Limited Morpholino-substituted bicycloheteroaryl compounds and their use as anti cancer agents
US7851484B2 (en) 2007-03-30 2010-12-14 Cytokinetics, Inc. Certain chemical entities, compositions, and methods
CA2713864A1 (en) * 2008-02-04 2009-08-13 Cytokinetics, Incorporated Certain chemical entities, compositions and methods
US7998976B2 (en) 2008-02-04 2011-08-16 Cytokinetics, Inc. Certain chemical entities, compositions and methods
EP2379561B1 (en) 2008-11-25 2015-11-04 University Of Rochester Mlk inhibitors and methods of use

Also Published As

Publication number Publication date
EP2244711A4 (en) 2011-08-24
ECSP10010432A (es) 2011-01-31
ECSP10010430A (es) 2011-02-28
CL2009000246A1 (es) 2009-06-26
CN101983061A (zh) 2011-03-02
JP2011510985A (ja) 2011-04-07
TW200946524A (en) 2009-11-16
US20090253737A1 (en) 2009-10-08
WO2009099594A1 (en) 2009-08-13
CO6290673A2 (es) 2011-06-20
AU2009210787A1 (en) 2009-08-13
AR072242A1 (es) 2010-08-18
CA2713864A1 (en) 2009-08-13
US7989469B2 (en) 2011-08-02
EA201001224A1 (ru) 2011-08-30
KR20100119773A (ko) 2010-11-10
IL207367A0 (en) 2010-12-30
EP2244711A1 (en) 2010-11-03
US20110312975A1 (en) 2011-12-22
BRPI0907502A2 (pt) 2019-01-15
MX2010008518A (es) 2010-11-10

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