ZA200900383B - Polymorphic forms and process - Google Patents

Polymorphic forms and process

Info

Publication number
ZA200900383B
ZA200900383B ZA200900383A ZA200900383A ZA200900383B ZA 200900383 B ZA200900383 B ZA 200900383B ZA 200900383 A ZA200900383 A ZA 200900383A ZA 200900383 A ZA200900383 A ZA 200900383A ZA 200900383 B ZA200900383 B ZA 200900383B
Authority
ZA
South Africa
Prior art keywords
polymorphic forms
polymorphic
forms
Prior art date
Application number
ZA200900383A
Other languages
English (en)
Inventor
Kai Schiemann
Ulrich Emde
Tobias Schlueter
Christoph Saal
Michael Maiwald
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA200900383B publication Critical patent/ZA200900383B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA200900383A 2006-06-19 2009-01-16 Polymorphic forms and process ZA200900383B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06012525 2006-06-19

Publications (1)

Publication Number Publication Date
ZA200900383B true ZA200900383B (en) 2010-01-27

Family

ID=38687475

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200900383A ZA200900383B (en) 2006-06-19 2009-01-16 Polymorphic forms and process

Country Status (19)

Country Link
US (1) US8198452B2 (xx)
EP (1) EP2032581B1 (xx)
JP (1) JP5322928B2 (xx)
KR (1) KR20090020702A (xx)
CN (1) CN101472928A (xx)
AR (1) AR061379A1 (xx)
AU (1) AU2007263393B2 (xx)
BR (1) BRPI0712393A2 (xx)
CA (1) CA2656064C (xx)
EA (1) EA015994B1 (xx)
EC (1) ECSP099077A (xx)
ES (1) ES2537759T3 (xx)
IL (1) IL195844A0 (xx)
MX (1) MX2008016071A (xx)
NZ (1) NZ574236A (xx)
PE (1) PE20080337A1 (xx)
TW (1) TW200815453A (xx)
WO (1) WO2007147480A2 (xx)
ZA (1) ZA200900383B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005027170A1 (de) * 2005-06-13 2006-12-14 Merck Patent Gmbh Substituierte Tetrahydrochinoline
DE102007021862A1 (de) * 2007-05-10 2008-11-13 Merck Patent Gmbh Wässrige pharmazeutische Zubereitung

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3345355A1 (de) * 1983-12-15 1985-06-27 Hoechst Ag, 6230 Frankfurt Verfahren zur racematspaltung bicyclischer imino-(alpha)-carbonsaeureester
DE4203547A1 (de) * 1992-02-07 1993-08-12 Knoll Ag Verfahren zur racemattrennung von verapamil
JPH07247286A (ja) * 1994-01-18 1995-09-26 Sankyo Co Ltd 含窒素環状化合物の光学分割方法
JPH07330732A (ja) * 1994-06-10 1995-12-19 Kyorin Pharmaceut Co Ltd 光学活性な３−アミノ−１−ベンジルピペリジン誘導体
GB0010437D0 (en) * 2000-04-28 2000-06-14 Darwin Discovery Ltd Process
US20040002615A1 (en) * 2002-06-28 2004-01-01 Allen David Robert Preparation of chiral amino-nitriles
EP2033959B1 (de) * 2003-12-20 2011-04-27 Merck Patent GmbH Tetrahydropyranochinolinderivate

Also Published As

Publication number Publication date
ECSP099077A (es) 2009-02-27
CN101472928A (zh) 2009-07-01
ES2537759T3 (es) 2015-06-11
US20090176820A1 (en) 2009-07-09
JP2009541231A (ja) 2009-11-26
JP5322928B2 (ja) 2013-10-23
EA015994B1 (ru) 2012-01-30
KR20090020702A (ko) 2009-02-26
EA200802400A1 (ru) 2009-06-30
CA2656064C (en) 2013-11-05
AU2007263393B2 (en) 2012-03-01
MX2008016071A (es) 2009-01-15
EP2032581B1 (en) 2015-03-11
WO2007147480A3 (en) 2008-05-08
IL195844A0 (en) 2009-09-01
PE20080337A1 (es) 2008-04-25
US8198452B2 (en) 2012-06-12
AU2007263393A1 (en) 2007-12-27
BRPI0712393A2 (pt) 2012-10-16
TW200815453A (en) 2008-04-01
EP2032581A2 (en) 2009-03-11
WO2007147480A2 (en) 2007-12-27
CA2656064A1 (en) 2007-12-27
AR061379A1 (es) 2008-08-20
NZ574236A (en) 2010-11-26

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