ZA200810677B - Fusion proteins, uses thereof and processes for producing same - Google Patents

Fusion proteins, uses thereof and processes for producing same

Info

Publication number
ZA200810677B
ZA200810677B ZA200810677A ZA200810677A ZA200810677B ZA 200810677 B ZA200810677 B ZA 200810677B ZA 200810677 A ZA200810677 A ZA 200810677A ZA 200810677 A ZA200810677 A ZA 200810677A ZA 200810677 B ZA200810677 B ZA 200810677B
Authority
ZA
South Africa
Prior art keywords
processes
fusion proteins
producing same
producing
same
Prior art date
Application number
ZA200810677A
Other languages
English (en)
Inventor
Yoram Reiter
Roy Noy
Kfir Oved
Original Assignee
Teva Pharma
Technion Res & Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma, Technion Res & Dev Foundation filed Critical Teva Pharma
Publication of ZA200810677B publication Critical patent/ZA200810677B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA200810677A 2006-05-19 2007-05-17 Fusion proteins, uses thereof and processes for producing same ZA200810677B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80179806P 2006-05-19 2006-05-19

Publications (1)

Publication Number Publication Date
ZA200810677B true ZA200810677B (en) 2010-03-31

Family

ID=38723866

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200810677A ZA200810677B (en) 2006-05-19 2007-05-17 Fusion proteins, uses thereof and processes for producing same

Country Status (16)

Country Link
US (4) US7977457B2 (zh)
EP (1) EP2024507B1 (zh)
JP (1) JP5225266B2 (zh)
KR (1) KR101442209B1 (zh)
CN (1) CN101448951B (zh)
AU (1) AU2007254167B2 (zh)
BR (1) BRPI0712716A2 (zh)
CA (1) CA2652538C (zh)
EA (1) EA200870555A1 (zh)
ES (1) ES2549128T3 (zh)
HK (1) HK1122335A1 (zh)
IL (1) IL195191A (zh)
MX (1) MX2008014722A (zh)
NO (1) NO342211B1 (zh)
WO (1) WO2007136778A2 (zh)
ZA (1) ZA200810677B (zh)

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Also Published As

Publication number Publication date
ES2549128T3 (es) 2015-10-23
EP2024507B1 (en) 2015-07-22
EA200870555A1 (ru) 2009-04-28
WO2007136778A3 (en) 2008-03-27
KR20090048397A (ko) 2009-05-13
JP5225266B2 (ja) 2013-07-03
AU2007254167B2 (en) 2012-11-15
NO20085272L (no) 2009-02-18
CA2652538A1 (en) 2007-11-29
BRPI0712716A2 (pt) 2012-05-22
HK1122335A1 (zh) 2009-05-15
JP2009537175A (ja) 2009-10-29
AU2007254167A1 (en) 2007-11-29
CN101448951B (zh) 2013-04-10
KR101442209B1 (ko) 2014-11-18
CA2652538C (en) 2016-06-28
US20080014208A1 (en) 2008-01-17
EP2024507A2 (en) 2009-02-18
US20110150874A1 (en) 2011-06-23
US20150152161A1 (en) 2015-06-04
EP2024507A4 (en) 2009-09-23
MX2008014722A (es) 2011-04-15
IL195191A (en) 2017-01-31
CN101448951A (zh) 2009-06-03
WO2007136778A2 (en) 2007-11-29
NO342211B1 (no) 2018-04-16
US20170211076A1 (en) 2017-07-27
US7977457B2 (en) 2011-07-12
IL195191A0 (en) 2009-08-03

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