ZA200810173B - Fast assignment of adequate neoadjuvant chemotherapy for breast cancer patients based on the identification of constitutional BRCA1 mutations - Google Patents
Fast assignment of adequate neoadjuvant chemotherapy for breast cancer patients based on the identification of constitutional BRCA1 mutationsInfo
- Publication number
- ZA200810173B ZA200810173B ZA200810173A ZA200810173A ZA200810173B ZA 200810173 B ZA200810173 B ZA 200810173B ZA 200810173 A ZA200810173 A ZA 200810173A ZA 200810173 A ZA200810173 A ZA 200810173A ZA 200810173 B ZA200810173 B ZA 200810173B
- Authority
- ZA
- South Africa
- Prior art keywords
- constitutional
- adequate
- identification
- breast cancer
- cancer patients
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL379827A PL217731B1 (pl) | 2006-06-01 | 2006-06-01 | Sposób wykrywania genetycznie uwarunkowanej obniżonej odpowiedzi na chemioterapię cytostatykiem taksanowym, zastosowanie mutacji założycielskiej oraz zestawu do wykrywania takiej odpowiedzi |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200810173B true ZA200810173B (en) | 2009-11-25 |
Family
ID=38779112
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200810173A ZA200810173B (en) | 2006-06-01 | 2008-11-28 | Fast assignment of adequate neoadjuvant chemotherapy for breast cancer patients based on the identification of constitutional BRCA1 mutations |
Country Status (8)
Country | Link |
---|---|
US (1) | US20080241834A1 (pl) |
EP (1) | EP2032720B1 (pl) |
AU (1) | AU2007268378A1 (pl) |
CA (1) | CA2650448A1 (pl) |
PL (1) | PL217731B1 (pl) |
RU (1) | RU2008146886A (pl) |
WO (1) | WO2007139411A2 (pl) |
ZA (1) | ZA200810173B (pl) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL212012B1 (pl) * | 2008-07-06 | 2012-07-31 | Tomasz Byrski | Wykrywanie podwyższonej podatności na chemioterapię z zastosowaniem cytostatyków platynowych |
WO2011057125A2 (en) * | 2009-11-05 | 2011-05-12 | Myriad Genetics, Inc. | Compositions and methods for determining cancer susceptibility |
RU2445372C1 (ru) * | 2010-09-15 | 2012-03-20 | Учреждение Российской академии медицинских наук Российский онкологический научный центр им. Н.Н. Блохина РАМН | СПОСОБ ОПРЕДЕЛЕНИЯ ГЕНОТИПА ЧЕЛОВЕКА ПО ПОЛИМОРФИЗМУ В ПОЗИЦИИ 6174 ГЕНА BRCA2 (617delT) |
RU2445373C1 (ru) * | 2010-09-15 | 2012-03-20 | Учреждение Российской академии медицинских наук Российский онкологический научный центр им. Н.Н. Блохина РАМН | СПОСОБ ОПРЕДЕЛЕНИЯ ГЕНОТИПА ЧЕЛОВЕКА ПО ПОЛИМОРФИЗМУ В ПОЗИЦИИ 4343 ГЕНА BRCA1 (rs1799950) |
RU2445371C1 (ru) * | 2010-09-15 | 2012-03-20 | Учреждение Российской академии медицинских наук Российский онкологический научный центр им. Н.Н. Блохина РАМН | СПОСОБ ОПРЕДЕЛЕНИЯ ГЕНОТИПА ЧЕЛОВЕКА ПО ПОЛИМОРФИЗМУ В ПОЗИЦИИ 2579 ГЕНА BRCA1 (rs4986850) |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2601676B1 (fr) | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Procede de preparation du taxol et du desacetyl-10 taxol |
FR2601675B1 (fr) | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
US4876399A (en) | 1987-11-02 | 1989-10-24 | Research Corporation Technologies, Inc. | Taxols, their preparation and intermediates thereof |
US4942184A (en) | 1988-03-07 | 1990-07-17 | The United States Of America As Represented By The Department Of Health And Human Services | Water soluble, antineoplastic derivatives of taxol |
US4960790A (en) | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
US5278324A (en) | 1990-08-28 | 1994-01-11 | Virginia Tech Intellectual Properties, Inc. | Water soluble derivatives of taxol |
US5710287A (en) | 1991-09-23 | 1998-01-20 | Florida State University | Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them |
US5283253A (en) | 1991-09-23 | 1994-02-01 | Florida State University | Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them |
WO1993021173A1 (en) | 1992-04-17 | 1993-10-28 | Abbott Laboratories | Taxol derivatives |
CA2119261C (en) | 1992-12-23 | 2006-01-31 | Michael A. Poss | Novel sidechain-bearing taxanes and intermediates thereof |
US5840929A (en) | 1995-04-14 | 1998-11-24 | Bristol-Myers Squibb Company | C4 methoxy ether derivatives of paclitaxel |
US5773629A (en) | 1996-06-14 | 1998-06-30 | Industrial Technology Research Institute | Synthesis of (4S, 5R) -2, 4-diphenyl-5-carboxy-oxazoline derivative as taxol side-chain precursor |
US5773464A (en) | 1996-09-30 | 1998-06-30 | Bristol-Myers Squibb Company | C-10 epoxy taxanes |
US5977386A (en) | 1996-12-24 | 1999-11-02 | Bristol-Myers Squibb Company | 6-thio-substituted paclitaxels |
US5902822A (en) | 1997-02-28 | 1999-05-11 | Bristol-Myers Squibb Company | 7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels |
US6017935A (en) | 1997-04-24 | 2000-01-25 | Bristol-Myers Squibb Company | 7-sulfur substituted paclitaxels |
CA2328771A1 (en) | 1997-12-31 | 1999-07-08 | Bristol-Myers Squibb Company | 2-aroyl-4-acyl paclitaxel (taxol) analogs |
JP2003506446A (ja) | 1999-08-11 | 2003-02-18 | ブリストル−マイヤーズ スクイブ カンパニー | パクリタキセルc−4メチルカーボネート類縁体の製造法 |
PL185957B1 (pl) | 1999-10-08 | 2003-09-30 | Tomasz Byrski | Sposób i zestaw diagnostyczny do wykrywania mutacji genów BRCA1 i BRCA2 w polskich rodzinach z agregacją raków sutka i/lub jajnika |
AR030188A1 (es) | 2000-02-02 | 2003-08-13 | Univ Florida State Res Found | Compuestos de taxano sustituidos con esteres en el c7; composiciones farmaceuticas que los contienen y proceso para tratar un sujeto mamifero que sufre de una condicion que responde a los taxanos |
US6750246B1 (en) | 2000-02-03 | 2004-06-15 | Bristol-Myers Squibb Company | C-4 carbonate taxanes |
US6916942B2 (en) | 2000-02-03 | 2005-07-12 | Bristol-Myers Squibb Company | Process for the preparation of C-4 carbonate taxanes |
US20030092019A1 (en) * | 2001-01-09 | 2003-05-15 | Millennium Pharmaceuticals, Inc. | Methods and compositions for diagnosing and treating neuropsychiatric disorders such as schizophrenia |
GB0226595D0 (en) * | 2002-11-15 | 2002-12-24 | Univ Belfast | Cancer therapy determination |
PL209997B1 (pl) | 2004-01-15 | 2011-11-30 | Tomasz Byrski | Sposób i zestaw do wykrywania wysokiej genetycznie uwarunkowanej predyspozycji do raka sutka i/lub jajnika u osoby pochodzenia polskiego oraz zastosowanie wybranych mutacji w obrębie genu BRCA1 |
US7563570B2 (en) * | 2004-10-29 | 2009-07-21 | Pangaea Biotech | Method of determining a chemotherapeutic regimen for non small cell lung cancer based on BRCA1 expression |
-
2006
- 2006-06-01 PL PL379827A patent/PL217731B1/pl unknown
-
2007
- 2007-06-01 CA CA002650448A patent/CA2650448A1/en not_active Abandoned
- 2007-06-01 US US11/809,574 patent/US20080241834A1/en not_active Abandoned
- 2007-06-01 AU AU2007268378A patent/AU2007268378A1/en not_active Abandoned
- 2007-06-01 WO PCT/PL2007/000035 patent/WO2007139411A2/en active Application Filing
- 2007-06-01 EP EP07747744.6A patent/EP2032720B1/en not_active Not-in-force
- 2007-06-01 RU RU2008146886/15A patent/RU2008146886A/ru unknown
-
2008
- 2008-11-28 ZA ZA200810173A patent/ZA200810173B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO2007139411A2 (en) | 2007-12-06 |
WO2007139411A3 (en) | 2008-07-17 |
PL379827A1 (pl) | 2007-12-10 |
PL217731B1 (pl) | 2014-08-29 |
AU2007268378A1 (en) | 2007-12-06 |
EP2032720B1 (en) | 2014-05-21 |
CA2650448A1 (en) | 2007-12-06 |
US20080241834A1 (en) | 2008-10-02 |
RU2008146886A (ru) | 2010-07-20 |
EP2032720A2 (en) | 2009-03-11 |
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