ZA200809493B - Method of treatment of age-related macular degeneration (AMD) - Google Patents

Method of treatment of age-related macular degeneration (AMD)

Info

Publication number
ZA200809493B
ZA200809493B ZA200809493A ZA200809493A ZA200809493B ZA 200809493 B ZA200809493 B ZA 200809493B ZA 200809493 A ZA200809493 A ZA 200809493A ZA 200809493 A ZA200809493 A ZA 200809493A ZA 200809493 B ZA200809493 B ZA 200809493B
Authority
ZA
South Africa
Prior art keywords
amd
age
treatment
macular degeneration
related macular
Prior art date
Application number
ZA200809493A
Other languages
English (en)
Inventor
Ashley Bush
Colin Louis Masters
Penelope Jane Huggins
Jack Gordon Parsons
Gaik Beng Kok
Vijaya Kenche
Sous Mariana El
Original Assignee
Prana Biotechnology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prana Biotechnology Ltd filed Critical Prana Biotechnology Ltd
Publication of ZA200809493B publication Critical patent/ZA200809493B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200809493A 2006-04-14 2007-04-13 Method of treatment of age-related macular degeneration (AMD) ZA200809493B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79227806P 2006-04-14 2006-04-14

Publications (1)

Publication Number Publication Date
ZA200809493B true ZA200809493B (en) 2010-08-25

Family

ID=38608967

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA200809493A ZA200809493B (en) 2006-04-14 2007-04-13 Method of treatment of age-related macular degeneration (AMD)
ZA2010/05922A ZA201005922B (en) 2006-04-14 2010-08-19 Method of treatment of age-related macular degeneration (amd)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA2010/05922A ZA201005922B (en) 2006-04-14 2010-08-19 Method of treatment of age-related macular degeneration (amd)

Country Status (14)

Country Link
US (3) US20100144693A1 (de)
EP (2) EP2012789B1 (de)
JP (1) JP5290147B2 (de)
KR (2) KR20080109096A (de)
CN (3) CN102225930A (de)
AU (2) AU2007240120A1 (de)
BR (2) BRPI0710737A2 (de)
CA (1) CA2683756A1 (de)
DK (1) DK2012789T3 (de)
ES (1) ES2437997T3 (de)
IL (1) IL207495A (de)
NZ (2) NZ572591A (de)
WO (1) WO2007118276A1 (de)
ZA (2) ZA200809493B (de)

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US8889695B2 (en) * 2008-12-24 2014-11-18 Prana Biotechnology Limited Quinazolinone compounds
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US11008290B2 (en) * 2015-09-24 2021-05-18 University Of Florida Research Foundation, Incorporated Halogenated quinoline derivatives as antimicrobial agents
JP7116490B2 (ja) 2016-05-09 2022-08-10 アルデイラ セラピューティクス， インコーポレイテッド 眼の炎症性障害および疾患の組合せ処置
WO2018000047A1 (en) * 2016-07-01 2018-01-04 Prana Biotechnology Limited Method of treating immunoglobulin light chain amyloidosis
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JP2023532134A (ja) * 2020-07-02 2023-07-26 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ 網膜変性の処置において使用するための環式化合物
CN113214249B (zh) * 2021-04-23 2023-09-19 成都大学 吡啶并[1,2-a]嘧啶-4-硫酮化合物的合成方法

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Also Published As

Publication number Publication date
EP2012789A4 (de) 2011-02-16
CN101987849B (zh) 2013-05-08
AU2010206074A1 (en) 2010-08-19
JP2009533356A (ja) 2009-09-17
EP2514423A2 (de) 2012-10-24
CN102225930A (zh) 2011-10-26
ZA201005922B (en) 2013-09-25
BRPI0722382A2 (pt) 2012-06-05
NZ572591A (en) 2012-01-12
AU2007240120A2 (en) 2008-12-18
EP2514423A3 (de) 2012-12-19
ES2437997T3 (es) 2014-01-15
NZ590271A (en) 2011-12-22
US9163018B2 (en) 2015-10-20
EP2012789B1 (de) 2013-09-25
US20100144693A1 (en) 2010-06-10
BRPI0710737A2 (pt) 2011-05-10
US20140088122A1 (en) 2014-03-27
IL207495A (en) 2015-05-31
CA2683756A1 (en) 2007-10-25
CN101534826A (zh) 2009-09-16
KR20100110396A (ko) 2010-10-12
CN101987849A (zh) 2011-03-23
DK2012789T3 (da) 2013-12-16
AU2010206074B2 (en) 2012-08-30
US20110071167A1 (en) 2011-03-24
AU2007240120A1 (en) 2007-10-25
EP2012789A1 (de) 2009-01-14
WO2007118276A1 (en) 2007-10-25
JP5290147B2 (ja) 2013-09-18
IL207495A0 (en) 2010-12-30
KR20080109096A (ko) 2008-12-16

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