ZA200803414B - Novel dihydropseudoerythromycin derivatives - Google Patents

Novel dihydropseudoerythromycin derivatives

Info

Publication number
ZA200803414B
ZA200803414B ZA200803414A ZA200803414A ZA200803414B ZA 200803414 B ZA200803414 B ZA 200803414B ZA 200803414 A ZA200803414 A ZA 200803414A ZA 200803414 A ZA200803414 A ZA 200803414A ZA 200803414 B ZA200803414 B ZA 200803414B
Authority
ZA
South Africa
Prior art keywords
derivatives
novel
novel dihydropseudoerythromycin
dihydropseudoerythromycin derivatives
compound
Prior art date
Application number
ZA200803414A
Other languages
English (en)
Inventor
Omura Satoshi
Sunazuka Toshiaki
Nagai Kenichiro
Shima Hideaki
Yamabe Haruko
Original Assignee
Kitasato Inst
Aphoenix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kitasato Inst, Aphoenix Inc filed Critical Kitasato Inst
Publication of ZA200803414B publication Critical patent/ZA200803414B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
ZA200803414A 2005-10-14 2006-10-13 Novel dihydropseudoerythromycin derivatives ZA200803414B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2005301070 2005-10-14

Publications (1)

Publication Number Publication Date
ZA200803414B true ZA200803414B (en) 2009-09-30

Family

ID=37942921

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200803414A ZA200803414B (en) 2005-10-14 2006-10-13 Novel dihydropseudoerythromycin derivatives

Country Status (18)

Country Link
US (1) US8133871B2 (fr)
EP (1) EP1950219B1 (fr)
JP (1) JP5118973B2 (fr)
KR (1) KR101384927B1 (fr)
CN (1) CN101326192B (fr)
AT (1) ATE513842T1 (fr)
AU (1) AU2006300215B2 (fr)
BR (1) BRPI0617391A2 (fr)
CA (1) CA2625055C (fr)
EA (1) EA015737B1 (fr)
ES (1) ES2369898T3 (fr)
IL (1) IL190643A (fr)
MY (1) MY147211A (fr)
NZ (1) NZ567772A (fr)
PL (1) PL1950219T3 (fr)
UA (1) UA94065C2 (fr)
WO (1) WO2007043710A1 (fr)
ZA (1) ZA200803414B (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102007011485A1 (de) 2007-03-07 2008-09-11 Grünenthal GmbH Darreichungsform mit erschwertem Missbrauch
EP2249811A1 (fr) 2008-01-25 2010-11-17 Grünenthal GmbH Forme posologique pharmaceutique
EP2273983B1 (fr) 2008-05-09 2016-07-20 Grünenthal GmbH Procédé de préparation d'une formulation de poudre intermédiaire et d'une forme galénique solide finale en utilisant une étape de congélation par pulvérisation
PL2456424T3 (pl) 2009-07-22 2013-12-31 Gruenenthal Gmbh Stabilizowana przed utlenianiem odporna na naruszenie postać dawkowania
PL2456427T3 (pl) 2009-07-22 2015-07-31 Gruenenthal Gmbh Wytłaczana na gorąco postać dawki o kontrolowanym uwalnianiu
AU2011297901B2 (en) 2010-09-02 2014-07-31 Grunenthal Gmbh Tamper resistant dosage form comprising inorganic salt
MX2013002293A (es) 2010-09-02 2013-05-09 Gruenenthal Gmbh Forma de dosificacion resistente a alteracion que comprende un polimero anionico.
US20130028972A1 (en) 2011-07-29 2013-01-31 Grunenthal Gmbh Tamper-resistant tablet providing immediate drug release
PE20141638A1 (es) 2011-07-29 2014-11-22 Gruenenthal Chemie Tableta a prueba de manipulacion que proporciona liberacion de farmaco inmediato
US20130225697A1 (en) 2012-02-28 2013-08-29 Grunenthal Gmbh Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
EA201401139A1 (ru) 2012-04-18 2015-03-31 Грюненталь Гмбх Устойчивая к разрушению и к сбросу дозы фармацевтическая лекарственная форма
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
MX2015016254A (es) 2013-05-29 2016-04-20 Gruenenthal Gmbh Forma de dosificacion resistente al uso indebido con perfil de liberacion bimodal.
JP6445537B2 (ja) 2013-05-29 2018-12-26 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング １個または複数の粒子を含有する改変防止（ｔａｍｐｅｒ−ｒｅｓｉｓｔａｎｔ）剤形
JP6449871B2 (ja) 2013-07-12 2019-01-09 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング エチレン−酢酸ビニルポリマーを含有する改変防止剤形
JP6480936B2 (ja) 2013-11-26 2019-03-13 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング クライオミリングによる粉末状医薬組成物の調製
WO2015173195A1 (fr) 2014-05-12 2015-11-19 Grünenthal GmbH Formulation pour capsule à libération immédiate résistant aux manipulations illicites comprenant du tapentadol
EP3148512A1 (fr) 2014-05-26 2017-04-05 Grünenthal GmbH Microparticules protégées contre une libération massive dans l'éthanol
WO2016154533A1 (fr) * 2015-03-25 2016-09-29 President And Fellows Of Harvard College Synthèse de désosamines
WO2016170097A1 (fr) 2015-04-24 2016-10-27 Grünenthal GmbH Forme galénique inviolable avec libération immédiate et résistance à l'extraction par solvant.
JP2018526414A (ja) 2015-09-10 2018-09-13 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 乱用抑止性の即放性製剤を用いた経口過剰摂取に対する保護

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
EP1489090B1 (fr) * 2000-08-17 2006-02-01 The Kitasato Institute Nouveaux dérivés de la pseudoérythromycine
JP2004522726A (ja) * 2000-12-01 2004-07-29 コーサン バイオサイエンシーズ， インコーポレイテッド モチリド化合物
US20020094962A1 (en) * 2000-12-01 2002-07-18 Gary Ashley Motilide compounds
US20040067896A1 (en) * 2002-07-25 2004-04-08 The Kitasato Institute Novel pseudoerythromycin derivatives
AU2002368309A1 (en) * 2002-10-29 2004-05-25 The Kitasato Institute Novel macrolide derivatives havaing effect of potentiating antifungal activity

Also Published As

Publication number Publication date
IL190643A0 (en) 2008-11-03
US8133871B2 (en) 2012-03-13
CA2625055A1 (fr) 2007-04-19
ATE513842T1 (de) 2011-07-15
US20090131341A1 (en) 2009-05-21
CA2625055C (fr) 2013-12-24
EP1950219A1 (fr) 2008-07-30
KR101384927B1 (ko) 2014-04-11
CN101326192A (zh) 2008-12-17
MY147211A (en) 2012-11-14
JPWO2007043710A1 (ja) 2009-07-16
EP1950219A4 (fr) 2010-02-03
AU2006300215B2 (en) 2012-06-21
UA94065C2 (en) 2011-04-11
ES2369898T3 (es) 2011-12-07
PL1950219T3 (pl) 2011-11-30
NZ567772A (en) 2010-07-30
BRPI0617391A2 (pt) 2011-07-26
WO2007043710A1 (fr) 2007-04-19
IL190643A (en) 2012-03-29
KR20080064861A (ko) 2008-07-09
JP5118973B2 (ja) 2013-01-16
EA200801083A1 (ru) 2009-02-27
CN101326192B (zh) 2012-06-20
WO2007043710A9 (fr) 2007-06-07
EA015737B1 (ru) 2011-10-31
AU2006300215A1 (en) 2007-04-19
EP1950219B1 (fr) 2011-06-22

Similar Documents

Publication Publication Date Title
ZA200803414B (en) Novel dihydropseudoerythromycin derivatives
EP1864665A4 (fr) Agent immunosuppressif et agent anti-tumoral comprenant un compose heterocyclique en tant que principe actif
WO2009057079A3 (fr) Nouveaux dérivés de pyrimidine
TNSN08407A1 (en) Organic compounds
WO2008120725A1 (fr) Nouveau dérivé de pyrrolinone et composition médicale le contenant
GEP20135803B (en) Dioxa-bicyclo[3.2.1.]octane-2,3,4-triol derivatives
TW200626598A (en) Pyrrazolo-pyrimidine derivatives
TW200800939A (en) Novel insecticides
EP2075011A3 (fr) Promédicaments contenant des liens disulfures bio-clivables
TW200744588A (en) Pharmaceutical composition for external use
MX2008001793A (es) Derivados de bisamida biciclica y uso de los mismos como insecticidas.
EP1736465A4 (fr) Dérivés d'aniline
GEP20094605B (en) Pyrazole derivatives, compositions containing such compounds and methods of use thereof
WO2009016560A3 (fr) Dérivés de trans-3-aza-bicyclo[3.1.0]hexane
WO2006100082A3 (fr) Derives d'oxindole substitues, medicaments contenant ces derives et leur utilisation
MX2007000392A (es) Derivados de 2-pirrolidona sustituida como fungicidas e insecticidas.
WO2009060835A8 (fr) Nouvelle petite molécule de liaison de l'ubiquitine
TW200633964A (en) Tetralin and indane derivatives and uses thereof
TW200728298A (en) Thiophene compounds and thrombopoietin receptor activators
MY186650A (en) Heteroaryl pyrrolidinyl and piperidinyl ketone derivatives
WO2007068728A3 (fr) Pyrrolopyridinones n-substituees actives en tant qu'inhibiteurs de kinase
IL229594A (en) Derived Lactone Derivatives, Pharmaceutical Compositions Containing Them and Their Uses in the Preparation of Medical Preparations for Cancer Treatment
WO2008093838A1 (fr) Dérivé de pyridyl imidazolidine ayant un groupe sulfamoyle, et utilisation pharmaceutique de ce dérivé
WO2007018941A3 (fr) Composes
WO2009075250A1 (fr) Agent phytosanitaire