ZA200802186B - Prion-specific peptoid reagents - Google Patents

Prion-specific peptoid reagents

Info

Publication number
ZA200802186B
ZA200802186B ZA200802186A ZA200802186A ZA200802186B ZA 200802186 B ZA200802186 B ZA 200802186B ZA 200802186 A ZA200802186 A ZA 200802186A ZA 200802186 A ZA200802186 A ZA 200802186A ZA 200802186 B ZA200802186 B ZA 200802186B
Authority
ZA
South Africa
Prior art keywords
prion
peptoid reagents
specific
specific peptoid
reagents
Prior art date
Application number
ZA200802186A
Other languages
English (en)
Inventor
Peretz David
Zuckermann Ronald
Robert M Shimizu
Michael D Connolly
Gao Man
Timoteo Gulliver
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ZA200802186B publication Critical patent/ZA200802186B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ZA200802186A 2005-09-09 2008-03-07 Prion-specific peptoid reagents ZA200802186B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US71576105P 2005-09-09 2005-09-09
US72668605P 2005-10-14 2005-10-14
US75893406P 2006-01-13 2006-01-13
PCT/US2006/035226 WO2007030804A1 (en) 2005-09-09 2006-09-08 Prion-specific peptoid reagents

Publications (1)

Publication Number Publication Date
ZA200802186B true ZA200802186B (en) 2008-12-31

Family

ID=37651167

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200802186A ZA200802186B (en) 2005-09-09 2008-03-07 Prion-specific peptoid reagents

Country Status (14)

Country Link
US (2) US7834144B2 (https=)
EP (2) EP2383281A3 (https=)
JP (2) JP5209477B2 (https=)
KR (1) KR20080048527A (https=)
CN (1) CN101356186A (https=)
AU (1) AU2006287299B2 (https=)
BR (1) BRPI0615618A2 (https=)
CA (1) CA2621767A1 (https=)
DK (1) DK1931695T3 (https=)
ES (1) ES2404940T3 (https=)
IL (1) IL189992A0 (https=)
NZ (2) NZ566020A (https=)
WO (1) WO2007030804A1 (https=)
ZA (1) ZA200802186B (https=)

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FR2892820B1 (fr) * 2005-11-03 2008-02-01 Diagast Soc Par Actions Simpli Procede magnetique d'immunodiagnostic pour la mise en evidence de complexe anticorps/antigene, en particulier de groupe sanguin
US9150612B2 (en) * 2007-02-23 2015-10-06 The Research Foundation Of State University Of New York RNA targeting compounds and methods for making and using same
US9260476B2 (en) 2007-02-23 2016-02-16 The Research Foundation For The State University Of New York RNA targeting compounds and methods for making and using same
WO2008124100A1 (en) * 2007-04-04 2008-10-16 Novartis Ag Prion elisa
ATE530914T1 (de) * 2007-04-04 2011-11-15 Novartis Ag Prionentest
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CA2721982A1 (en) * 2008-04-30 2009-11-05 Novartis Ag Assay for pathogenic conformers
WO2010017412A1 (en) * 2008-08-06 2010-02-11 The Regents Of The University Of California Novel biomimetic peptoid polymers
US8828413B2 (en) * 2009-02-24 2014-09-09 New York University Peptoid oligomers, pharmaceutical compositions and methods of using the same
BRPI1013012A2 (pt) 2009-06-02 2016-10-18 Opko Health Inc identificação de pequenas moléculas reconhecidas por anticorpos em indivíduos com doenças neurodegenerativas
EP2496947A1 (en) * 2009-11-04 2012-09-12 Novartis AG Positively charged species as binding reagents in the separation of protein aggregates from monomers
US8952127B2 (en) 2010-06-04 2015-02-10 The Regents Of The University Of California Peptoids useful for catalyzing the mineralization of calcium carbonate
WO2013043669A1 (en) * 2011-09-21 2013-03-28 The Board Of Regents Of The University Of Texas System Peptoid compositions for the treatment of alzheimer's disease and polyglutamine expansion disorder
US10391068B2 (en) * 2012-08-06 2019-08-27 Trustees Of Boston University Prion protein ligands as therapeutic agents for neurodegenerative disorders
US9764953B2 (en) 2013-03-20 2017-09-19 The Regents Of The University Of California Peptoids useful for the mineralization of apatite
CN107529753A (zh) * 2015-03-11 2018-01-02 卢莫斯制药公司 环肌酸及其类似物的合成
MX391259B (es) 2015-10-14 2025-03-21 X Therma Inc Composiciones y métodos para reducir la formación de cristales de hielo.
EP3426672B1 (en) 2016-03-09 2021-09-01 Mike-Ann, LLC Peptoid affinity ligands
CA3057150A1 (en) 2017-04-12 2018-10-18 X-Therma, Inc. Novel peptoid polymers and methods of use
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Also Published As

Publication number Publication date
NZ594844A (en) 2013-04-26
US20120027677A1 (en) 2012-02-02
AU2006287299A1 (en) 2007-03-15
EP2383281A3 (en) 2012-01-04
CA2621767A1 (en) 2007-03-15
EP1931695B1 (en) 2013-04-10
IL189992A0 (en) 2008-08-07
JP2009507833A (ja) 2009-02-26
WO2007030804A1 (en) 2007-03-15
KR20080048527A (ko) 2008-06-02
US20070087972A1 (en) 2007-04-19
EP2383281A2 (en) 2011-11-02
DK1931695T3 (da) 2013-07-01
NZ566020A (en) 2012-08-31
AU2006287299B2 (en) 2012-08-23
CN101356186A (zh) 2009-01-28
US7834144B2 (en) 2010-11-16
JP5209477B2 (ja) 2013-06-12
JP2012162571A (ja) 2012-08-30
BRPI0615618A2 (pt) 2011-05-24
ES2404940T3 (es) 2013-05-29
EP1931695A1 (en) 2008-06-18

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