ZA200802007B - 1,3-disubstituted indole derivatives for use as PPAR modulators - Google Patents

1,3-disubstituted indole derivatives for use as PPAR modulators

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Publication number
ZA200802007B
ZA200802007B ZA200802007A ZA200802007A ZA200802007B ZA 200802007 B ZA200802007 B ZA 200802007B ZA 200802007 A ZA200802007 A ZA 200802007A ZA 200802007 A ZA200802007 A ZA 200802007A ZA 200802007 B ZA200802007 B ZA 200802007B
Authority
ZA
South Africa
Prior art keywords
indole derivatives
ppar modulators
disubstituted indole
disubstituted
ppar
Prior art date
Application number
ZA200802007A
Other languages
English (en)
Inventor
Lin Jack
Lee Byunghun
Zhang Chao
Dean R Artis
Wang Weiru
Womack Patrick
Shi Shenghua
Zuckerman Rebecca
Prabha N Ibrahim
Original Assignee
Plexxikon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plexxikon Inc filed Critical Plexxikon Inc
Publication of ZA200802007B publication Critical patent/ZA200802007B/xx

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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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