ZA200801362B - Solid pharmaceutical dosage form - Google Patents
Solid pharmaceutical dosage form Download PDFInfo
- Publication number
- ZA200801362B ZA200801362B ZA200801362A ZA200801362A ZA200801362B ZA 200801362 B ZA200801362 B ZA 200801362B ZA 200801362 A ZA200801362 A ZA 200801362A ZA 200801362 A ZA200801362 A ZA 200801362A ZA 200801362 B ZA200801362 B ZA 200801362B
- Authority
- ZA
- South Africa
- Prior art keywords
- dosage form
- weight
- solid
- surfactant
- water
- Prior art date
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
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- A61K9/2833—Organic macromolecular compounds
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- A—HUMAN NECESSITIES
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| EP1175205B1 (en) * | 1999-11-12 | 2006-06-14 | Abbott Laboratories | Solid dispersion comprising ritonavir, fenofibrate or griseofulvin |
| US20050048112A1 (en) | 2003-08-28 | 2005-03-03 | Jorg Breitenbach | Solid pharmaceutical dosage form |
| US8025899B2 (en) * | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
| US8377952B2 (en) * | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
| AU2012202831B2 (en) * | 2005-02-23 | 2015-01-22 | Abbvie Inc. | A solid pharmaceutical dosage formulation |
| KR20070025070A (ko) * | 2005-08-31 | 2007-03-08 | 주식회사 대웅제약 | 시부트라민 및 계면활성제를 함유하는 고체분산체 및 그의제조방법 |
| RU2008128424A (ru) * | 2005-12-14 | 2010-01-20 | Сипла Лимитед (In) | Фармацевтическая комбинация, включающая нуклеотидный и нуклеозидный ингибиторы обратной транскриптазы (такие как тенофовир и ламивудин) в различных частях дозы |
| DK1962808T3 (da) * | 2005-12-14 | 2010-11-08 | Hoffmann La Roche | HCV prodrug-formulering |
| US20090136570A1 (en) * | 2006-01-20 | 2009-05-28 | Bhagwant Rege | Taste-Masked Tablets and Granules |
| EP1832281A1 (en) * | 2006-03-10 | 2007-09-12 | Abbott GmbH & Co. KG | Process for producing a solid dispersion of an active ingredient |
| EP1880715A1 (en) * | 2006-07-19 | 2008-01-23 | Abbott GmbH & Co. KG | Pharmaceutically acceptable solubilizing composition and pharmaceutical dosage form containing same |
| CL2007002331A1 (es) * | 2006-08-10 | 2008-04-18 | Cipla Ltd | Composicion oral solida que comprede uno o mas farmacos antirretrovirales y al menos un polimero insoluble en agua, en relacion aproximadamente 1:1 hasta 1:6; proceso de elaboracion; y uso para el tratamiento del vih. |
| WO2008067164A2 (en) | 2006-11-15 | 2008-06-05 | Abbott Laboratories | Solid pharmaceutical dosage formulations |
| PL3150586T3 (pl) | 2007-02-23 | 2020-06-01 | Gilead Sciences, Inc. | Modulatory farmakokinetycznych właściwości środków terapeutycznych |
| PA8809601A1 (es) * | 2007-12-24 | 2009-07-23 | Cipla Ltd | Combinación anti-retroviral |
| EP3272337A3 (en) * | 2008-02-28 | 2018-02-14 | AbbVie Inc. | Tablets |
| WO2009153654A1 (en) * | 2008-06-17 | 2009-12-23 | Aurobindo Pharma Limited | Solid dosage forms of antiretrovirals |
| ME02640B (me) * | 2008-10-07 | 2017-06-20 | Kudos Pharm Ltd | Farmaceutske formulacije 514 |
| EP2391350A1 (en) | 2008-12-18 | 2011-12-07 | Ranbaxy Laboratories Limited | Atazanavir formulations |
| TW201043269A (en) * | 2009-04-14 | 2010-12-16 | Bristol Myers Squibb Co | Bioavailable compositions of amorphous alpha-(N-sulfonamido)acetamide compound |
| TWI471321B (zh) | 2009-06-08 | 2015-02-01 | Abbott Gmbh & Co Kg | Ｂｃｌ－２族群抑制劑之口服醫藥劑型 |
| WO2011013110A1 (en) | 2009-07-31 | 2011-02-03 | Ranbaxy Laboratories Limited | Unit dosage forms of hiv protease inhibitors |
| US20110034489A1 (en) | 2009-07-31 | 2011-02-10 | Ranbaxy Laboratories Limited | Solid dosage forms of hiv protease inhibitors |
| UA113500C2 (xx) | 2010-10-29 | 2017-02-10 | Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб | |
| EP2683378A4 (en) * | 2011-03-07 | 2014-09-03 | Hetero Research Foundation | AMORPHOUS FORM OF A MIXTURE OF LOPINAVIR AND RITONAVIR |
| CA2837266A1 (en) | 2011-05-27 | 2012-12-06 | Hetero Research Foundation | Amorphous ritonavir co-precipitated |
| WO2013025449A1 (en) * | 2011-08-16 | 2013-02-21 | Merck Sharp & Dohme Corp. | Use of inorganic matrix and organic polymer combinations for preparing stable amorphous dispersions |
| EP2564832A1 (en) | 2011-08-29 | 2013-03-06 | Hexal AG | Solid dosage form of HIV protease inhibitors |
| KR101794032B1 (ko) * | 2011-09-21 | 2017-11-07 | (주)바이오시네틱스 | 나노입자 제조방법 |
| ES2586912T3 (es) * | 2012-03-07 | 2016-10-19 | Ratiopharm Gmbh | Forma de dosificación que comprende lopinavir no cristalino y ritonavir cristalino |
| CA2866206A1 (en) | 2012-03-07 | 2013-09-12 | Ratiopharm Gmbh | Dosage form comprising lopinavir and ritonavir |
| CN103655571B (zh) * | 2012-09-11 | 2016-04-20 | 上海星泰医药科技有限公司 | 一种洛匹那韦和利托那韦复方高均匀度纳米共分散体及其制备方法 |
| WO2014048782A1 (en) | 2012-09-27 | 2014-04-03 | Basf Se | A storage-stable dust-free homogeneous particulate formulation comprising at least one water-soluble vitamin e-derivative and at least one hydrophilic polymer |
| US9744240B2 (en) | 2012-09-27 | 2017-08-29 | Basf Se | Storage-stable dust-free homogeneous particulate formulation comprising at least one water-soluble vitamin E-derivative and at least one hydrophilic polymer |
| JP6301339B2 (ja) | 2012-09-27 | 2018-03-28 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | 少なくとも１種の水溶性ビタミンｅ誘導体および少なくとも１種の親水性ポリマーを含む、保存において安定な無塵の均質な粒子製剤 |
| US9789063B2 (en) | 2012-09-27 | 2017-10-17 | Basf Se | Storage-stable dust-free homogeneous particulate formulation |
| RU2505286C1 (ru) | 2012-12-29 | 2014-01-27 | Открытое Акционерное Общество "Фармасинтез" | Фармацевтическая композиция для лечения вич-инфекции, способ ее получения и способ лечения |
| RU2543322C1 (ru) * | 2013-09-19 | 2015-02-27 | Открытое Акционерное Общество "Фармасинтез" | Фармацевтическая композиция для лечения вич-инфекции, способ ее получения и способ лечения |
| RU2619840C1 (ru) * | 2016-09-21 | 2017-05-18 | Общество с ограниченной ответственностью "Изварино Фарма" | Фармацевтическая композиция для лечения ВИЧ-инфекции |
| RU2659693C1 (ru) * | 2017-06-30 | 2018-07-03 | Общество с ограниченной ответственностью "Изварино Фарма" | Фармацевтическая композиция, обладающая активностью против ВИЧ-инфекции |
| US20190038754A1 (en) * | 2017-08-07 | 2019-02-07 | SE Tylose, USA, Inc. | Pharmaceutical composition in solid extruded form |
| US20210361639A1 (en) * | 2018-03-02 | 2021-11-25 | The University Of Liverpool | Solid compositions of actives, processes for preparing same and uses of such solid compositions |
| CN108186578A (zh) * | 2018-03-27 | 2018-06-22 | 聊城大学 | 一种利托那韦固体分散体的制备方法 |
| EP3569225A1 (en) | 2018-05-18 | 2019-11-20 | Pharmaceutical Oriented Services Ltd | Solid dispersion containing ritonavir |
| TWI799599B (zh) * | 2019-06-06 | 2023-04-21 | 華納國際生物科技股份有限公司 | 醫藥或保健品自乳化固體分散組成物 |
| CN114146061B (zh) * | 2020-09-07 | 2023-06-30 | 歌礼生物科技（杭州）有限公司 | 包含固体分散体的蛋白酶抑制剂增效组合物及其制备方法 |
| CN113318076B (zh) * | 2021-06-02 | 2022-09-23 | 聊城大学 | 一种兼具增溶及抑晶效果的利托那韦固体分散体及其制备方法 |
| CN114557967B (zh) * | 2022-03-17 | 2023-06-02 | 乐普制药科技有限公司 | 一种利托那韦固体分散体的制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2525108B1 (fr) | 1982-04-19 | 1989-05-12 | Elan Corp Ltd | Medicaments a haut degre de solubilite et procede pour leur obtention |
| DE3830353A1 (de) | 1988-09-07 | 1990-03-15 | Basf Ag | Verfahren zur kontinuierlichen herstellung von festen pharmazeutischen formen |
| US5539122A (en) * | 1989-05-23 | 1996-07-23 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| US5354866A (en) * | 1989-05-23 | 1994-10-11 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| US5542206A (en) | 1994-10-11 | 1996-08-06 | Lisch; Albert | Lure and tackle stacking container |
| US5914332A (en) * | 1995-12-13 | 1999-06-22 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| US6232333B1 (en) * | 1996-11-21 | 2001-05-15 | Abbott Laboratories | Pharmaceutical composition |
| US6027747A (en) * | 1997-11-11 | 2000-02-22 | Terracol; Didier | Process for the production of dry pharmaceutical forms and the thus obtained pharmaceutical compositions |
| DE19841244A1 (de) * | 1998-09-09 | 2000-03-16 | Knoll Ag | Verfahren und Vorrichtung zum Herstellen von Tabletten |
| EP1027886B1 (en) | 1999-02-10 | 2008-07-09 | Pfizer Products Inc. | Pharmaceutical solid dispersions |
| US20030104048A1 (en) * | 1999-02-26 | 2003-06-05 | Lipocine, Inc. | Pharmaceutical dosage forms for highly hydrophilic materials |
| DE19913692A1 (de) * | 1999-03-25 | 2000-09-28 | Basf Ag | Mechanisch stabile pharmazeutische Darreichungsformen, enthaltend flüssige oder halbfeste oberflächenaktive Substanzen |
| DE19913606A1 (de) | 1999-03-25 | 2000-09-28 | Basf Ag | Pulverförmige Solubilisationshilfsstoffe für feste pharmazeutische Darreichungsformen |
| CA2371109C (en) | 1999-06-04 | 2011-04-26 | Laman A. Alani | Improved pharmaceutical formulations |
| EP1175205B1 (en) * | 1999-11-12 | 2006-06-14 | Abbott Laboratories | Solid dispersion comprising ritonavir, fenofibrate or griseofulvin |
| PT1227797E (pt) | 1999-11-12 | 2005-05-31 | Abbott Lab | Formulacoes farmaceuticas de dispersao solida |
| WO2003000294A1 (en) | 2001-06-22 | 2003-01-03 | Pfizer Products Inc. | Pharmaceutical compositions containing a solid dispersion of a poorly-soluble drug in a matrix and a solubility-enhancing polymer |
| ATE395044T1 (de) * | 2002-02-01 | 2008-05-15 | Pfizer Prod Inc | Pharmazeutische zusammensetzungen amorpher dispersionen von wirkstoffen und lipophiler mikrophasenbildender materialien |
| DE10213242A1 (de) * | 2002-03-25 | 2003-10-16 | Abbott Gmbh & Co Kg | Testsystem zur Evaluierung der Kompatibilität biologisch aktiver Substanzen mit Copolymeren |
| DE10247037A1 (de) * | 2002-10-09 | 2004-04-22 | Abbott Gmbh & Co. Kg | Herstellung von festen Dosierungsformen unter Verwendung eines vernetzten nichtthermoplastischen Trägers |
| US20050048112A1 (en) | 2003-08-28 | 2005-03-03 | Jorg Breitenbach | Solid pharmaceutical dosage form |
| US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
| WO2008067164A2 (en) | 2006-11-15 | 2008-06-05 | Abbott Laboratories | Solid pharmaceutical dosage formulations |
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2003
- 2003-08-28 US US10/650,178 patent/US20050048112A1/en not_active Abandoned
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2004
- 2004-08-23 EA EA201301045A patent/EA033224B1/ru not_active IP Right Cessation
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- 2004-08-23 DK DK10181250.1T patent/DK2258344T3/da active
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- 2004-08-23 EP EP15169378.5A patent/EP2942051B1/en active Active
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- 2004-08-23 CN CN200480024748XA patent/CN1901884B/zh not_active Ceased
- 2004-08-23 KR KR1020147007592A patent/KR101563222B1/ko active IP Right Grant
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- 2004-08-23 EP EP10181268.3A patent/EP2258346B1/en not_active Revoked
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- 2004-08-23 MX MXPA06002346A patent/MXPA06002346A/es active IP Right Grant
- 2004-08-23 EP EP17210362.4A patent/EP3354261A1/en not_active Withdrawn
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- 2004-08-23 AU AU2004283087A patent/AU2004283087C1/en not_active Revoked
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- 2004-08-23 CN CN2012102597395A patent/CN102764244A/zh active Pending
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- 2004-08-23 DK DK04816820.7T patent/DK1663183T3/da active
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- 2004-08-23 SI SI200432412T patent/SI2258346T1/sl unknown
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- 2004-08-23 DK DK10181264.2T patent/DK2258345T3/en active
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- 2004-08-23 EA EA200900292A patent/EA020992B1/ru not_active IP Right Cessation
- 2004-08-23 PL PL10181268T patent/PL2258346T3/pl unknown
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- 2004-08-23 DK DK15169378.5T patent/DK2942051T3/en active
- 2004-08-23 PL PL15169378T patent/PL2942051T3/pl unknown
- 2004-08-23 KR KR1020067004057A patent/KR101132602B1/ko active IP Right Grant
- 2004-08-23 KR KR1020127011945A patent/KR101457967B1/ko active IP Right Grant
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- 2004-08-23 SI SI200432367A patent/SI2258345T1/sl unknown
- 2004-08-23 SG SG10201507902UA patent/SG10201507902UA/en unknown
- 2004-08-23 KR KR1020117025014A patent/KR101281994B1/ko active IP Right Grant
- 2004-08-23 EP EP04816820A patent/EP1663183B9/en not_active Revoked
- 2004-08-27 TW TW093125927A patent/TWI342221B/zh active
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2006
- 2006-02-23 CR CR8256A patent/CR8256A/es unknown
- 2006-02-24 EC EC2006006397A patent/ECSP066397A/es unknown
- 2006-02-26 IL IL173939A patent/IL173939A/en active IP Right Grant
- 2006-02-27 ZA ZA200601718A patent/ZA200601718B/xx unknown
- 2006-03-24 NO NO20061342A patent/NO330282B1/no not_active Application Discontinuation
- 2006-12-06 HK HK06113444.9A patent/HK1094766A1/xx not_active IP Right Cessation
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2007
- 2007-12-19 AU AU2007249115A patent/AU2007249115B2/en not_active Revoked
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2008
- 2008-02-08 ZA ZA2008/01361A patent/ZA200801361B/en unknown
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2010
- 2010-03-15 NO NO20100367A patent/NO334418B1/no not_active Application Discontinuation
- 2010-07-27 IL IL207260A patent/IL207260A/en active IP Right Grant
- 2010-11-01 AU AU2010238573A patent/AU2010238573B2/en not_active Revoked
- 2010-12-30 HK HK10112283.9A patent/HK1145969A1/xx not_active IP Right Cessation
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2011
- 2011-02-18 JP JP2011032972A patent/JP5498411B2/ja active Active
- 2011-07-06 JP JP2011149721A patent/JP5395125B2/ja active Active
- 2011-07-25 HR HR20110555T patent/HRP20110555T1/hr unknown
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2012
- 2012-12-21 CR CR20120661A patent/CR20120661A/es unknown
- 2012-12-21 CR CR20120662A patent/CR20120662A/es unknown
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2013
- 2013-02-01 CY CY20131100093T patent/CY1113596T1/el unknown
- 2013-08-13 JP JP2013168001A patent/JP5903413B2/ja active Active
- 2013-12-27 NO NO20131743A patent/NO335326B1/no not_active Application Discontinuation
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2015
- 2015-12-04 JP JP2015237449A patent/JP2016094433A/ja not_active Withdrawn
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2016
- 2016-05-10 HK HK16105307.9A patent/HK1217298A1/zh not_active IP Right Cessation
- 2016-12-19 CY CY20161101315T patent/CY1118505T1/el unknown
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2017
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- 2017-09-18 IL IL254581A patent/IL254581A0/en unknown
- 2017-11-03 CY CY20171101155T patent/CY1119651T1/el unknown
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2018
- 2018-04-17 CY CY20181100407T patent/CY1120138T1/el unknown
- 2018-12-19 HK HK18116294.9A patent/HK1257502A1/zh unknown
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