SG10201507902UA - Solid pharmaceutical dosage form - Google Patents

Solid pharmaceutical dosage form

Info

Publication number
SG10201507902UA
SG10201507902UA SG10201507902UA SG10201507902UA SG10201507902UA SG 10201507902U A SG10201507902U A SG 10201507902UA SG 10201507902U A SG10201507902U A SG 10201507902UA SG 10201507902U A SG10201507902U A SG 10201507902UA SG 10201507902U A SG10201507902U A SG 10201507902UA
Authority
SG
Singapore
Prior art keywords
dosage form
pharmaceutical dosage
solid pharmaceutical
pharmaceutically acceptable
hiv protease
Prior art date
Application number
SG10201507902UA
Inventor
Jöerg ROSENBERG
Ulrich Reinhold
Bernd Liepold
Gunther Derndl
Jörg Breitenbach
Laman Alani
Soumojeet Ghosh
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34217089&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201507902U(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of SG10201507902UA publication Critical patent/SG10201507902UA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A solid pharmaceutical dosage form providing improved oral bioavailability is disclosed for inhibitors of HIV protease. In particular, the dosage form comprises a solid dispersion of at least one HIV protease inhibitor in at least one pharmaceutically acceptable water-soluble polymer and at least one pharmaceutically acceptable surfactant.
SG10201507902UA 2003-08-28 2004-08-23 Solid pharmaceutical dosage form SG10201507902UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/650,178 US20050048112A1 (en) 2003-08-28 2003-08-28 Solid pharmaceutical dosage form
SG2006010474 2004-08-23

Publications (1)

Publication Number Publication Date
SG10201507902UA true SG10201507902UA (en) 2015-10-29

Family

ID=34217089

Family Applications (3)

Application Number Title Priority Date Filing Date
SG2012008959A SG179401A1 (en) 2003-08-28 2004-08-23 Solid pharmaceutical dosage form comprising an hiv protease inhibitor solid dispersion
SG10201507902UA SG10201507902UA (en) 2003-08-28 2004-08-23 Solid pharmaceutical dosage form
SG200805563-4A SG145690A1 (en) 2003-08-28 2004-08-23 Solid pharmaceutical dosage form comprising an hiv protease inhibitor solid dispersion

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2012008959A SG179401A1 (en) 2003-08-28 2004-08-23 Solid pharmaceutical dosage form comprising an hiv protease inhibitor solid dispersion

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG200805563-4A SG145690A1 (en) 2003-08-28 2004-08-23 Solid pharmaceutical dosage form comprising an hiv protease inhibitor solid dispersion

Country Status (31)

Country Link
US (1) US20050048112A1 (en)
EP (6) EP2258345B1 (en)
JP (6) JP4815348B2 (en)
KR (5) KR20150044031A (en)
CN (5) CN105106104A (en)
AT (1) ATE516017T1 (en)
AU (3) AU2004283087C1 (en)
CA (2) CA2536638C (en)
CR (3) CR8256A (en)
CY (5) CY1111981T1 (en)
DK (5) DK2942051T3 (en)
EA (4) EA201890737A3 (en)
EC (1) ECSP066397A (en)
ES (5) ES2653762T3 (en)
HK (4) HK1094766A1 (en)
HR (1) HRP20110555T1 (en)
HU (3) HUE031153T2 (en)
IL (3) IL173939A (en)
ME (2) MEP17608A (en)
MX (2) MXPA06002346A (en)
NO (3) NO330282B1 (en)
NZ (2) NZ545499A (en)
PL (5) PL1663183T3 (en)
PT (5) PT2942051T (en)
RS (2) RS59969B1 (en)
SG (3) SG179401A1 (en)
SI (5) SI2942051T1 (en)
TW (1) TWI342221B (en)
UA (1) UA85564C2 (en)
WO (1) WO2005039551A2 (en)
ZA (3) ZA200801362B (en)

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CN103655571B (en) * 2012-09-11 2016-04-20 上海星泰医药科技有限公司 A kind of Lopinavir and ritonavir compound recipe high evenness nanometer are divided into prose style free from parallelism and preparation method thereof
EP2911651B1 (en) 2012-09-27 2016-06-22 Basf Se A storage-stable dust-free homogeneous particulate formulation comprising at least one water-soluble vitamin e-derivative and at least one hydrophilic polymer
US9789063B2 (en) 2012-09-27 2017-10-17 Basf Se Storage-stable dust-free homogeneous particulate formulation
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Also Published As

Publication number Publication date
ES2653762T3 (en) 2018-02-08
HUE035985T2 (en) 2018-06-28
PT2258345T (en) 2017-01-20
KR101457967B1 (en) 2014-11-07
SG145690A1 (en) 2008-09-29
RS20181262A1 (en) 2019-02-28
CR20120662A (en) 2013-03-13
PL1663183T3 (en) 2011-10-31
SI2258345T1 (en) 2017-01-31
AU2010238573A1 (en) 2010-11-18
JP5395125B2 (en) 2014-01-22
DK1663183T3 (en) 2011-08-29
CN102772380B (en) 2015-08-19
AU2007249115A1 (en) 2008-01-10
WO2005039551A2 (en) 2005-05-06
CR20120661A (en) 2013-03-13
TWI342221B (en) 2011-05-21
CN101919858A (en) 2010-12-22
RS59969B1 (en) 2020-03-31
EP2258345A3 (en) 2011-01-19
IL173939A0 (en) 2006-07-05
PT2258344E (en) 2013-02-18
ES2399810T3 (en) 2013-04-03
JP2011236232A (en) 2011-11-24
KR20060121837A (en) 2006-11-29
EA201301045A1 (en) 2014-05-30
PT2258346T (en) 2017-10-24
ZA200801361B (en) 2011-11-30
EA200900292A1 (en) 2009-06-30
NO20061342L (en) 2006-05-29
PL2258345T3 (en) 2017-03-31
AU2010238573B2 (en) 2012-12-13
NO20131743L (en) 2006-05-29
CY1119651T1 (en) 2018-04-04
DK2258345T3 (en) 2017-01-16
ZA200601718B (en) 2009-11-25
EP2258345B1 (en) 2016-09-21
CA2689639C (en) 2014-06-10
CN102764244A (en) 2012-11-07
MX358033B (en) 2018-08-02
KR101132602B1 (en) 2012-04-06
HUE031153T2 (en) 2017-07-28
NO335326B1 (en) 2014-11-10
KR101563222B1 (en) 2015-10-26
SI2258344T1 (en) 2013-03-29
IL254581A0 (en) 2017-11-30
EP1663183B1 (en) 2011-07-13
SI2942051T1 (en) 2018-06-29
KR20150044031A (en) 2015-04-23
ES2608720T3 (en) 2017-04-12
JP5498411B2 (en) 2014-05-21
NO334418B1 (en) 2014-03-03
CY1118505T1 (en) 2017-07-12
CY1113596T1 (en) 2016-06-22
DK2942051T3 (en) 2018-05-07
JP2018035163A (en) 2018-03-08
EA201890737A2 (en) 2018-08-31
EA011924B1 (en) 2009-06-30
RS20060140A (en) 2008-09-29
CN102772380A (en) 2012-11-14
KR20140046078A (en) 2014-04-17
KR20120054666A (en) 2012-05-30
NZ545499A (en) 2009-11-27
MXPA06002346A (en) 2006-05-19
CA2536638C (en) 2010-04-06
EP2258344B1 (en) 2012-11-14
CY1111981T1 (en) 2015-11-04
ES2367173T3 (en) 2011-10-31
JP2011126898A (en) 2011-06-30
ES2666390T3 (en) 2018-05-04
RS57663B1 (en) 2018-11-30
SI2258346T1 (en) 2017-12-29
SI1663183T1 (en) 2011-09-30
TW200522979A (en) 2005-07-16
PL2942051T3 (en) 2018-07-31
ATE516017T1 (en) 2011-07-15
IL207260A (en) 2017-10-31
PL2258346T3 (en) 2018-01-31
EP2942051A1 (en) 2015-11-11
UA85564C2 (en) 2009-02-10
DK2258344T3 (en) 2013-01-02
DK2258346T3 (en) 2017-11-13
EP2258344A3 (en) 2011-01-19
IL173939A (en) 2017-03-30
AU2004283087B2 (en) 2007-09-20
NZ579622A (en) 2011-01-28
JP2016094433A (en) 2016-05-26
ME00130B (en) 2010-10-10
CA2689639A1 (en) 2005-05-06
JP2007504142A (en) 2007-03-01
NO20100367L (en) 2006-05-29
CY1120138T1 (en) 2018-12-12
ECSP066397A (en) 2006-08-30
US20050048112A1 (en) 2005-03-03
JP5903413B2 (en) 2016-04-13
SG179401A1 (en) 2012-04-27
EP2258344A2 (en) 2010-12-08
MEP17608A (en) 2010-06-10
EP2258346A2 (en) 2010-12-08
EA033224B1 (en) 2019-09-30
KR101281994B1 (en) 2013-07-04
HK1217298A1 (en) 2017-01-06
AU2004283087A1 (en) 2005-05-06
EP2258346B1 (en) 2017-09-27
EP2942051B1 (en) 2018-01-17
EP1663183B9 (en) 2012-06-13
HK1257502A1 (en) 2019-10-25
PT2942051T (en) 2018-04-23
HK1094766A1 (en) 2007-04-13
EP1663183A2 (en) 2006-06-07
EP2258346A3 (en) 2011-01-19
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