ZA200800889B - Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof - Google Patents
Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereofInfo
- Publication number
- ZA200800889B ZA200800889B ZA200800889A ZA200800889A ZA200800889B ZA 200800889 B ZA200800889 B ZA 200800889B ZA 200800889 A ZA200800889 A ZA 200800889A ZA 200800889 A ZA200800889 A ZA 200800889A ZA 200800889 B ZA200800889 B ZA 200800889B
- Authority
- ZA
- South Africa
- Prior art keywords
- methods
- polynucleotides encoding
- modifying enzymes
- isoprenoid modifying
- encoding isoprenoid
- Prior art date
Links
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 102000040430 polynucleotide Human genes 0.000 title 1
- 108091033319 polynucleotide Proteins 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 title 1
- 150000003505 terpenes Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
- C12N9/0038—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
- C12N9/0042—NADPH-cytochrome P450 reductase (1.6.2.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y106/00—Oxidoreductases acting on NADH or NADPH (1.6)
- C12Y106/02—Oxidoreductases acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
- C12Y106/02004—NADPH-hemoprotein reductase (1.6.2.4), i.e. NADP-cytochrome P450-reductase
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Nutrition Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69706705P | 2005-07-05 | 2005-07-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200800889B true ZA200800889B (en) | 2009-09-30 |
Family
ID=37605033
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200800889A ZA200800889B (en) | 2005-07-05 | 2006-06-29 | Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US8163980B2 (https=) |
| EP (2) | EP2489672B1 (https=) |
| JP (1) | JP2009504138A (https=) |
| KR (2) | KR101487304B1 (https=) |
| CN (4) | CN105950667A (https=) |
| AP (1) | AP3827A (https=) |
| BR (1) | BRPI0612411B8 (https=) |
| CA (1) | CA2613469C (https=) |
| DK (1) | DK1919514T3 (https=) |
| ES (2) | ES2386554T3 (https=) |
| IL (1) | IL188376A (https=) |
| MX (1) | MX2008000200A (https=) |
| PL (1) | PL1919514T3 (https=) |
| PT (1) | PT1919514E (https=) |
| SG (1) | SG176459A1 (https=) |
| SI (1) | SI1919514T1 (https=) |
| WO (1) | WO2007005604A2 (https=) |
| ZA (1) | ZA200800889B (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0513837B1 (pt) | 2004-07-27 | 2021-10-13 | The Regents Of The University Of California | Célula hospedeira saccharomyces cerevisiae geneticamente modificada; composição compreendendo a mesma e método para aumentar a produção de isoprenoides |
| WO2007005604A2 (en) * | 2005-07-05 | 2007-01-11 | The Regents Of The University Of California | Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof |
| SG172646A1 (en) | 2006-05-26 | 2011-07-28 | Amyris Biotechnologies Inc | Production of isoprenoids |
| DK2066778T3 (en) * | 2006-09-26 | 2016-04-18 | Amyris Biotechnologies Inc | PREPARATION OF ISOPRENOIDS AND ISOPRENOID PRECURSORS |
| EP2171085A4 (en) | 2007-06-01 | 2010-07-14 | Sapphire Energy | SCREENING OF GENETICALLY MODIFIED PHOTOSYNTHETIC ORGANISMS WITH HIGH THROUGHPUT |
| CA2698289A1 (en) | 2007-09-11 | 2009-03-19 | Sapphire Energy, Inc. | Methods of producing organic products with photosynthetic organisms and products and compositions thereof |
| EP2444415A1 (en) * | 2010-10-20 | 2012-04-25 | Genoplante-Valor | 1-Deoxy-D-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis |
| PL2773751T3 (pl) | 2011-11-01 | 2017-08-31 | Firmenich Sa | Cytochrom 450 i jego zastosowanie w enzymatycznym utlenianiu terpenów |
| JP5827601B2 (ja) * | 2012-07-04 | 2015-12-02 | 住友ゴム工業株式会社 | 特定の蛋白質の発現を光応答転写因子により調整する方法、光応答転写因子をコードする遺伝子が導入されたイソプレノイド産生植物、及び該イソプレノイド産生植物を用いたポリイソプレノイドの製造方法 |
| JP2015533483A (ja) * | 2012-09-07 | 2015-11-26 | サノフイ | メタボリックシンドロームを治療するための融合タンパク質 |
| PL224377B1 (pl) * | 2012-11-02 | 2016-12-30 | Inst Biochemii I Biofizyki Polskiej Akademii Nauk | Szczep Trichoderma atroviride, sposób otrzymywania i zastosowanie szczepu Trichoderma atroviride jako środka biobójczego |
| US9909145B2 (en) * | 2013-09-19 | 2018-03-06 | Firmenich Sa | Method for producing fragrant alcohols |
| EP3184639B1 (en) * | 2014-08-21 | 2019-06-12 | Chung-Ang University Industry-Academy Cooperation Foundation | Rdna nts based gene multiple insertion cassette set and gras-grade recombinant yeast strain |
| US11697830B2 (en) * | 2015-04-15 | 2023-07-11 | Ramon Gonzalez | Iterative platform for the synthesis of alpha functionalized products |
| US20180142273A1 (en) * | 2015-04-15 | 2018-05-24 | William Marsh Rice University | Iterative platform for the synthesis of alpha functionalized products |
| CN105274109B (zh) * | 2015-10-30 | 2017-12-29 | 上海交通大学 | 一种调控基因在非分泌型腺毛中表达的启动子及其应用 |
| CN105177007B (zh) * | 2015-10-30 | 2017-11-10 | 上海交通大学 | 一种调控基因在非分泌型腺毛中表达的启动子及其应用 |
| CN105483236A (zh) * | 2015-12-26 | 2016-04-13 | 吉林省农业科学院 | 转基因植物中cry1C基因的LAMP检测引物组、试剂盒及检测方法 |
| CN105567685B (zh) * | 2016-01-18 | 2018-07-13 | 上海交通大学 | AaPDR3基因启动子及其应用 |
| EP3516048B1 (en) | 2016-09-20 | 2023-01-11 | 22nd Century Limited, LLC | Trichome specific promoters for the manipulation of cannabinoids and other compounds in glandular trichomes |
| WO2018111194A1 (en) * | 2016-12-16 | 2018-06-21 | Temasek Life Sciences Laboratory Limited | Targets for improving terpene production in rhodosporidium toruloides |
| BR112019019966A2 (pt) | 2017-03-24 | 2020-04-28 | Trait Biosciences Inc | biossíntese in vivo de alto nível e isolamento de canabinoides solúveis em água em sistemas de plantas |
| CN111465700A (zh) | 2017-07-11 | 2020-07-28 | 特征生物科学公司 | 在酵母和植物细胞悬浮培养物中产生水溶性大麻素化合物和材料组合物 |
| US11905543B2 (en) | 2017-07-11 | 2024-02-20 | Trait Biosceinces, Inc. | In vivo generation of water-soluble acetylated cannabinoid glycoside compounds in plant cell suspension cultures |
| US11946059B2 (en) | 2017-07-11 | 2024-04-02 | Trait Biosciences, Inc. | In vivo generation of water-soluble cannabinoids in plant cell suspension cultures |
| CN113302298B (zh) | 2018-11-09 | 2025-02-25 | 银杏生物制品公司 | 罗汉果甙的生物合成 |
| CA3165502A1 (en) * | 2020-01-23 | 2021-07-29 | Christopher J. Paddon | Amorpha-4,11-diene 12-monooxygenase variants and uses thereof |
| CN111621508B (zh) * | 2020-06-11 | 2022-07-01 | 云南中烟工业有限责任公司 | 烟草萜类合成酶NtTPS7基因及其载体与应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5451513A (en) | 1990-05-01 | 1995-09-19 | The State University of New Jersey Rutgers | Method for stably transforming plastids of multicellular plants |
| WO1993020206A1 (en) * | 1992-03-27 | 1993-10-14 | International Flower Developments Pty. Ltd. | Genetic sequences encoding flavonoid pathway enzymes and uses therefor |
| FR2689905B1 (fr) * | 1992-04-13 | 1995-07-13 | Orsan | Procede de clonage d'une sequence d'adn codant pour une nadph cytochrome p450 reductase et sequences d'adn codant pour une nadph-cytochrome p450 reductase, notamment de plantes. |
| US5576198A (en) | 1993-12-14 | 1996-11-19 | Calgene, Inc. | Controlled expression of transgenic constructs in plant plastids |
| US5545817A (en) | 1994-03-11 | 1996-08-13 | Calgene, Inc. | Enhanced expression in a plant plastid |
| US5545818A (en) | 1994-03-11 | 1996-08-13 | Calgene Inc. | Expression of Bacillus thuringiensis cry proteins in plant plastids |
| KR100551104B1 (ko) | 1994-12-09 | 2006-02-09 | 임페리얼 컬리지 이노베이션스 리미티드 | 유전자의 동정 |
| TR199902183T2 (xx) * | 1997-03-07 | 1999-12-21 | Novartis Ag | Sitokrom P450 monoksigenazlar |
| US6900012B1 (en) | 1997-06-03 | 2005-05-31 | The University Of Chicago | Plant artificial chromosome compositions and methods |
| US6083731A (en) * | 1997-06-24 | 2000-07-04 | Washington State University Research Foundation | Recombinant materials and methods for the production of limonene hydroxylases |
| US6080849A (en) | 1997-09-10 | 2000-06-27 | Vion Pharmaceuticals, Inc. | Genetically modified tumor-targeted bacteria with reduced virulence |
| EP0982404A1 (en) * | 1998-08-27 | 2000-03-01 | Wallaart, Thorvald Eelco | DNA encoding amorpha-4,11-diene synthase |
| US6645747B1 (en) | 1999-09-21 | 2003-11-11 | E. I. Du Pont De Nemours And Company | Cis-prenyltransferases from plants |
| US6369212B1 (en) | 2000-02-07 | 2002-04-09 | Korea Kumbo Petrochemical Co., Ltd. | Cytochrome P450 gene highly expressed in the incompatible interaction |
| EP1354955A4 (en) * | 2000-12-28 | 2005-01-05 | Toyota Motor Co Ltd | PROCESS FOR PREPARING PRENYL ALCOHOL |
| GB0105924D0 (en) | 2001-03-09 | 2001-04-25 | Microscience Ltd | Promoter |
| US7405057B2 (en) * | 2001-03-09 | 2008-07-29 | Board Of Trustees Of The University Of Kentucky | Cytochrome P450s and uses thereof |
| AUPR446701A0 (en) * | 2001-04-18 | 2001-05-17 | Gene Stream Pty Ltd | Transgenic mammals for pharmacological and toxicological studies |
| WO2003025193A1 (en) | 2001-09-17 | 2003-03-27 | Plant Research International B.V. | Plant enzymes for bioconversion |
| US20040162420A1 (en) * | 2002-10-16 | 2004-08-19 | U.S. Smokeless Tobacco Company | Cloning of cytochrome p450 genes from nicotiana |
| US7192751B2 (en) | 2001-12-06 | 2007-03-20 | The Regents Of The University Of California | Biosynthesis of amorpha-4,11-diene |
| US7172886B2 (en) * | 2001-12-06 | 2007-02-06 | The Regents Of The University Of California | Biosynthesis of isopentenyl pyrophosphate |
| US6733996B2 (en) | 2002-08-26 | 2004-05-11 | Trustees Of Dartmouth College | Methods for regulating gene expression using light |
| WO2007005604A2 (en) * | 2005-07-05 | 2007-01-11 | The Regents Of The University Of California | Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof |
| CA2630305A1 (en) * | 2005-10-24 | 2007-05-03 | National Research Council Of Canada | A novel gene encoding amorphadiene hydroxylase and a process to produce artemisinic alcohol therewith |
-
2006
- 2006-06-29 WO PCT/US2006/025572 patent/WO2007005604A2/en not_active Ceased
- 2006-06-29 CN CN201610412819.8A patent/CN105950667A/zh active Pending
- 2006-06-29 CN CN2006800246664A patent/CN101495499B/zh active Active
- 2006-06-29 ZA ZA200800889A patent/ZA200800889B/xx unknown
- 2006-06-29 BR BRPI0612411A patent/BRPI0612411B8/pt active IP Right Grant
- 2006-06-29 PL PL06785959T patent/PL1919514T3/pl unknown
- 2006-06-29 CN CN201710271576.5A patent/CN106939323B/zh active Active
- 2006-06-29 JP JP2008519611A patent/JP2009504138A/ja not_active Withdrawn
- 2006-06-29 AP AP2013006962A patent/AP3827A/en active
- 2006-06-29 PT PT06785959T patent/PT1919514E/pt unknown
- 2006-06-29 ES ES06785959T patent/ES2386554T3/es active Active
- 2006-06-29 KR KR1020137011897A patent/KR101487304B1/ko active Active
- 2006-06-29 CA CA2613469A patent/CA2613469C/en active Active
- 2006-06-29 SI SI200631367T patent/SI1919514T1/sl unknown
- 2006-06-29 MX MX2008000200A patent/MX2008000200A/es active IP Right Grant
- 2006-06-29 ES ES12158465.0T patent/ES2621657T3/es active Active
- 2006-06-29 DK DK06785959.5T patent/DK1919514T3/da active
- 2006-06-29 CN CN201310335874.8A patent/CN103667370B/zh active Active
- 2006-06-29 EP EP12158465.0A patent/EP2489672B1/en active Active
- 2006-06-29 SG SG2011081403A patent/SG176459A1/en unknown
- 2006-06-29 EP EP06785959A patent/EP1919514B1/en active Active
- 2006-06-29 US US11/917,875 patent/US8163980B2/en active Active
- 2006-06-29 KR KR1020087002992A patent/KR101444090B1/ko active Active
-
2007
- 2007-12-24 IL IL188376A patent/IL188376A/en active IP Right Grant
-
2012
- 2012-03-21 US US13/426,387 patent/US8759632B2/en active Active
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