KR101487304B1 - 이소프레노이드 변형 효소를 코드화하는 폴리뉴클레오티드 및 그것의 사용방법 - Google Patents

이소프레노이드 변형 효소를 코드화하는 폴리뉴클레오티드 및 그것의 사용방법 Download PDF

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KR101487304B1
KR101487304B1 KR1020137011897A KR20137011897A KR101487304B1 KR 101487304 B1 KR101487304 B1 KR 101487304B1 KR 1020137011897 A KR1020137011897 A KR 1020137011897A KR 20137011897 A KR20137011897 A KR 20137011897A KR 101487304 B1 KR101487304 B1 KR 101487304B1
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host cell
nucleic acid
isoprenoid
nucleotide sequence
leu
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KR20130054468A (ko
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대균 노
카린 뉴만
에릭 엠. 파라다이스
제이 디. 키슬링
마리오 웰레
레이첼 이추스
킴벌리 호
티모디 햄
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더 리젠츠 오브 더 유니버시티 오브 캘리포니아
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C12N9/0038—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12N9/0042—NADPH-cytochrome P450 reductase (1.6.2.4)
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    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y106/00—Oxidoreductases acting on NADH or NADPH (1.6)
    • C12Y106/02—Oxidoreductases acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12Y106/02004—NADPH-hemoprotein reductase (1.6.2.4), i.e. NADP-cytochrome P450-reductase

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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
KR1020137011897A 2005-07-05 2006-06-29 이소프레노이드 변형 효소를 코드화하는 폴리뉴클레오티드 및 그것의 사용방법 Active KR101487304B1 (ko)

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US69706705P 2005-07-05 2005-07-05
US60/697,067 2005-07-05
PCT/US2006/025572 WO2007005604A2 (en) 2005-07-05 2006-06-29 Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof

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KR1020087002992A Division KR101444090B1 (ko) 2005-07-05 2006-06-29 이소프레노이드 변형 효소를 코드화하는 폴리뉴클레오티드및 그것의 사용방법

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KR20130054468A KR20130054468A (ko) 2013-05-24
KR101487304B1 true KR101487304B1 (ko) 2015-01-28

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KR1020137011897A Active KR101487304B1 (ko) 2005-07-05 2006-06-29 이소프레노이드 변형 효소를 코드화하는 폴리뉴클레오티드 및 그것의 사용방법
KR1020087002992A Active KR101444090B1 (ko) 2005-07-05 2006-06-29 이소프레노이드 변형 효소를 코드화하는 폴리뉴클레오티드및 그것의 사용방법

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US (2) US8163980B2 (https=)
EP (2) EP2489672B1 (https=)
JP (1) JP2009504138A (https=)
KR (2) KR101487304B1 (https=)
CN (4) CN105950667A (https=)
AP (1) AP3827A (https=)
BR (1) BRPI0612411B8 (https=)
CA (1) CA2613469C (https=)
DK (1) DK1919514T3 (https=)
ES (2) ES2386554T3 (https=)
IL (1) IL188376A (https=)
MX (1) MX2008000200A (https=)
PL (1) PL1919514T3 (https=)
PT (1) PT1919514E (https=)
SG (1) SG176459A1 (https=)
SI (1) SI1919514T1 (https=)
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WO2007005604A2 (en) * 2005-07-05 2007-01-11 The Regents Of The University Of California Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof
SG172646A1 (en) 2006-05-26 2011-07-28 Amyris Biotechnologies Inc Production of isoprenoids
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EP2171085A4 (en) 2007-06-01 2010-07-14 Sapphire Energy SCREENING OF GENETICALLY MODIFIED PHOTOSYNTHETIC ORGANISMS WITH HIGH THROUGHPUT
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EP2444415A1 (en) * 2010-10-20 2012-04-25 Genoplante-Valor 1-Deoxy-D-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis
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JP5827601B2 (ja) * 2012-07-04 2015-12-02 住友ゴム工業株式会社 特定の蛋白質の発現を光応答転写因子により調整する方法、光応答転写因子をコードする遺伝子が導入されたイソプレノイド産生植物、及び該イソプレノイド産生植物を用いたポリイソプレノイドの製造方法
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CN105274109B (zh) * 2015-10-30 2017-12-29 上海交通大学 一种调控基因在非分泌型腺毛中表达的启动子及其应用
CN105177007B (zh) * 2015-10-30 2017-11-10 上海交通大学 一种调控基因在非分泌型腺毛中表达的启动子及其应用
CN105483236A (zh) * 2015-12-26 2016-04-13 吉林省农业科学院 转基因植物中cry1C基因的LAMP检测引物组、试剂盒及检测方法
CN105567685B (zh) * 2016-01-18 2018-07-13 上海交通大学 AaPDR3基因启动子及其应用
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WO2018111194A1 (en) * 2016-12-16 2018-06-21 Temasek Life Sciences Laboratory Limited Targets for improving terpene production in rhodosporidium toruloides
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US8163980B2 (en) 2012-04-24
CN106939323B (zh) 2021-07-13
CN106939323A (zh) 2017-07-11
JP2009504138A (ja) 2009-02-05
EP1919514B1 (en) 2012-05-16
US20120288905A1 (en) 2012-11-15
CA2613469C (en) 2014-08-12
AP2013006962A0 (en) 2013-07-31
EP2489672A3 (en) 2013-01-09
CN105950667A (zh) 2016-09-21
ES2621657T3 (es) 2017-07-04
MX2008000200A (es) 2008-04-07
EP1919514A4 (en) 2009-12-02
HK1134495A1 (en) 2010-04-30
CN101495499A (zh) 2009-07-29
BRPI0612411A8 (pt) 2017-12-26
ZA200800889B (en) 2009-09-30
IL188376A0 (en) 2008-04-13
SG176459A1 (en) 2011-12-29
SI1919514T1 (sl) 2012-08-31
IL188376A (en) 2012-12-31
KR20080031054A (ko) 2008-04-07
CN103667370A (zh) 2014-03-26
DK1919514T3 (da) 2012-08-20
KR101444090B1 (ko) 2014-09-26
WO2007005604A3 (en) 2008-12-31
CN101495499B (zh) 2013-09-04
KR20130054468A (ko) 2013-05-24
EP2489672A2 (en) 2012-08-22
WO2007005604A2 (en) 2007-01-11
EP2489672B1 (en) 2017-01-18
ES2386554T3 (es) 2012-08-22
EP1919514A2 (en) 2008-05-14
BRPI0612411A2 (pt) 2010-11-09
CN103667370B (zh) 2016-08-10
US20100218283A1 (en) 2010-08-26
BRPI0612411B1 (pt) 2020-05-05
PT1919514E (pt) 2012-08-16
US8759632B2 (en) 2014-06-24
PL1919514T3 (pl) 2012-10-31
AP3827A (en) 2016-09-30
CA2613469A1 (en) 2007-01-11
BRPI0612411B8 (pt) 2021-05-25

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