ZA200800412B - Substituted cyclic compound, its preparation process and its medical use - Google Patents

Substituted cyclic compound, its preparation process and its medical use

Info

Publication number
ZA200800412B
ZA200800412B ZA200800412A ZA200800412A ZA200800412B ZA 200800412 B ZA200800412 B ZA 200800412B ZA 200800412 A ZA200800412 A ZA 200800412A ZA 200800412 A ZA200800412 A ZA 200800412A ZA 200800412 B ZA200800412 B ZA 200800412B
Authority
ZA
South Africa
Prior art keywords
preparation process
medical use
cyclic compound
substituted cyclic
substituted
Prior art date
Application number
ZA200800412A
Other languages
English (en)
Inventor
Wang Mingwei
Wang Guangxing
Liu Qing
Nan Fajun
Li Na
Xie Xin
Zhou Caihong
Original Assignee
Shanghai Inst Materia Medica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Inst Materia Medica filed Critical Shanghai Inst Materia Medica
Publication of ZA200800412B publication Critical patent/ZA200800412B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C233/06—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C233/07—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Peptides Or Proteins (AREA)
  • Detergent Compositions (AREA)
ZA200800412A 2005-06-24 2008-01-14 Substituted cyclic compound, its preparation process and its medical use ZA200800412B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNA200510027131XA CN1884278A (zh) 2005-06-24 2005-06-24 一类胰高血糖样肽－1受体调节剂、制备方法和用途

Publications (1)

Publication Number Publication Date
ZA200800412B true ZA200800412B (en) 2008-10-29

Family

ID=37570110

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200800412A ZA200800412B (en) 2005-06-24 2008-01-14 Substituted cyclic compound, its preparation process and its medical use

Country Status (14)

Country Link
US (1) US8039492B2 (ru)
EP (1) EP1900721B1 (ru)
JP (1) JP4825266B2 (ru)
KR (1) KR100928475B1 (ru)
CN (1) CN1884278A (ru)
AU (1) AU2006261472B8 (ru)
BR (1) BRPI0613310A2 (ru)
CA (1) CA2613155C (ru)
IL (1) IL188199A (ru)
MX (1) MX2007016125A (ru)
RU (1) RU2378254C2 (ru)
UA (1) UA101297C2 (ru)
WO (1) WO2006136101A1 (ru)
ZA (1) ZA200800412B (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1884278A (zh) 2005-06-24 2006-12-27 中国科学院上海药物研究所 一类胰高血糖样肽－1受体调节剂、制备方法和用途
CN101195613B (zh) * 2006-12-05 2012-08-08 中国科学院上海药物研究所 一类具有取代四元环结构的化合物及其医学用途
CN101195585A (zh) * 2006-12-05 2008-06-11 中国科学院上海药物研究所 一类具有取代环己烷结构的化合物、及其制备方法和医学用途
CN101195612B (zh) * 2006-12-05 2012-08-08 中国科学院上海药物研究所 一类具有取代环丁烷结构的化合物、及其制备方法和医学用途
CN101195584A (zh) * 2006-12-05 2008-06-11 中国科学院上海药物研究所 一类具有取代环丙烷结构的化合物、制备方法及其医学用途
CN101195586A (zh) * 2006-12-05 2008-06-11 中国科学院上海药物研究所 一类具有取代环戊烷结构的化合物、制备方法及其医学用途
CN101274927B (zh) * 2007-03-29 2011-04-27 中国科学院上海药物研究所 一类四元环状化合物的光化学反应制备方法及其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100453533C (zh) * 2003-12-12 2009-01-21 中国科学院上海药物研究所 一类胰高血糖样肽－1受体激动剂及其制备方法和用途
CN1884278A (zh) 2005-06-24 2006-12-27 中国科学院上海药物研究所 一类胰高血糖样肽－1受体调节剂、制备方法和用途

Also Published As

Publication number Publication date
EP1900721A1 (en) 2008-03-19
CA2613155C (en) 2011-06-07
IL188199A (en) 2011-12-29
BRPI0613310A2 (pt) 2010-12-28
KR20080021811A (ko) 2008-03-07
AU2006261472B8 (en) 2010-05-13
UA101297C2 (ru) 2013-03-25
WO2006136101A1 (fr) 2006-12-28
US8039492B2 (en) 2011-10-18
IL188199A0 (en) 2008-03-20
CA2613155A1 (en) 2006-12-28
AU2006261472B2 (en) 2010-04-22
JP4825266B2 (ja) 2011-11-30
EP1900721A4 (en) 2010-04-07
US20100168183A1 (en) 2010-07-01
RU2378254C2 (ru) 2010-01-10
MX2007016125A (es) 2008-03-06
AU2006261472A1 (en) 2006-12-28
EP1900721B1 (en) 2013-05-08
RU2008101661A (ru) 2009-07-27
KR100928475B1 (ko) 2009-11-25
CN1884278A (zh) 2006-12-27
JP2008543889A (ja) 2008-12-04

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