ZA200703624B - Glucuronide metabolites and epimers thereof of tigecycline - Google Patents

Glucuronide metabolites and epimers thereof of tigecycline

Info

Publication number
ZA200703624B
ZA200703624B ZA200703624A ZA200703624A ZA200703624B ZA 200703624 B ZA200703624 B ZA 200703624B ZA 200703624 A ZA200703624 A ZA 200703624A ZA 200703624 A ZA200703624 A ZA 200703624A ZA 200703624 B ZA200703624 B ZA 200703624B
Authority
ZA
South Africa
Prior art keywords
tigecycline
epimers
glucuronide metabolites
glucuronide
metabolites
Prior art date
Application number
ZA200703624A
Other languages
English (en)
Inventor
Ronald A Jordon
Demaio William
Hoffman Matthew
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of ZA200703624B publication Critical patent/ZA200703624B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200703624A 2004-11-05 2007-05-04 Glucuronide metabolites and epimers thereof of tigecycline ZA200703624B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62512104P 2004-11-05 2004-11-05

Publications (1)

Publication Number Publication Date
ZA200703624B true ZA200703624B (en) 2009-10-28

Family

ID=36337018

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200703624A ZA200703624B (en) 2004-11-05 2007-05-04 Glucuronide metabolites and epimers thereof of tigecycline

Country Status (22)

Country Link
US (1) US7534766B2 (zh)
EP (1) EP1807441A2 (zh)
JP (1) JP2008519038A (zh)
KR (1) KR20070085761A (zh)
CN (1) CN101132799A (zh)
AR (1) AR051236A1 (zh)
AU (1) AU2005304957A1 (zh)
BR (1) BRPI0517715A (zh)
CA (1) CA2586245A1 (zh)
CR (1) CR9111A (zh)
GT (1) GT200500320A (zh)
HN (1) HN2005030775A (zh)
IL (1) IL182640A0 (zh)
MX (1) MX2007005105A (zh)
NO (1) NO20072226L (zh)
PA (1) PA8652001A1 (zh)
PE (1) PE20061048A1 (zh)
RU (1) RU2007116800A (zh)
SV (1) SV2006002294A (zh)
TW (1) TW200628485A (zh)
WO (1) WO2006052717A2 (zh)
ZA (1) ZA200703624B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8217155B2 (en) * 2007-07-31 2012-07-10 Gilead Colorado, Inc. Metabolites and derivatives of ambrisentan
US8766177B2 (en) 2010-10-11 2014-07-01 University Of North Texas Nanomanipulation coupled nanospray mass spectrometry (NMS)
JP6134191B2 (ja) 2013-04-07 2017-05-24 村川 惠美 回転型セミバッチａｌｄ装置

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494903A (en) 1991-10-04 1996-02-27 American Cyanamid Company 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
EP0536515B1 (en) 1991-10-04 2001-12-19 American Cyanamid Company Novel 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
SG47520A1 (en) 1992-08-13 1998-04-17 American Cyanamid Co New method for the production of 9-amino-6-demethyl-6-deoxytetracycline
US5284963A (en) 1992-08-13 1994-02-08 American Cyanamid Company Method of producing 7-(substituted)-9-[(substituted glycyl)-amidol]-6-demethyl-6-deoxytetra-cyclines
US5328902A (en) 1992-08-13 1994-07-12 American Cyanamid Co. 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
US5420272A (en) 1992-08-13 1995-05-30 American Cyanamid Company 7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
WO2005009944A1 (en) 2003-07-09 2005-02-03 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
CN101863841A (zh) 2003-07-09 2010-10-20 帕拉特克药品公司 取代的四环素化合物
US20050148553A1 (en) 2003-09-05 2005-07-07 Testa Raymond T. Use of tigecycline, alone, or in combination with rifampin to treat osteomyelitis and/or septic arthritis

Also Published As

Publication number Publication date
US7534766B2 (en) 2009-05-19
WO2006052717A2 (en) 2006-05-18
MX2007005105A (es) 2007-06-26
EP1807441A2 (en) 2007-07-18
PE20061048A1 (es) 2006-11-15
HN2005030775A (es) 2006-12-18
TW200628485A (en) 2006-08-16
US20060128950A1 (en) 2006-06-15
AU2005304957A1 (en) 2006-05-18
IL182640A0 (en) 2007-07-24
GT200500320A (es) 2006-06-02
SV2006002294A (es) 2006-10-13
AR051236A1 (es) 2006-12-27
CR9111A (es) 2008-01-21
RU2007116800A (ru) 2008-12-10
CA2586245A1 (en) 2006-05-18
PA8652001A1 (es) 2006-10-13
WO2006052717A3 (en) 2007-11-15
NO20072226L (no) 2007-06-04
JP2008519038A (ja) 2008-06-05
BRPI0517715A (pt) 2008-10-21
KR20070085761A (ko) 2007-08-27
CN101132799A (zh) 2008-02-27

Similar Documents

Publication Publication Date Title
IL187303A0 (en) Methods of prepering 3 - cyano - quinolines and intermediates made thereby
IL187360A0 (en) Tigecycline and methods of preparation
IL187539A0 (en) Tigecycline and methods of preparing 9-nitrominocycline
IL187532A0 (en) Methods of synthesizing substituted 3- cyanoquinolines and intermediates thereof
ZA200710154B (en) Tigecycline and methods of preparing 9-aminominocycline
ZA200710174B (en) Methods of purifying tigecycline
ZA200710151B (en) Crystalline solid forms of tigecycline and methods of preparing same
HK1083341A1 (en) Stable crystal of 4-oxoquinoline compound
WO2007070538A9 (en) Anti-mn antibodies and methods of using same
EP1909961A4 (en) FASTENING CROSS AND FASTENING PROCESS
PT2380573E (pt) Acetato de eslicarbazepina e métodos de utilização
ZA200703624B (en) Glucuronide metabolites and epimers thereof of tigecycline
TW586639U (en) Expanding structure of display
ZA200802775B (en) 9-aminocarbonylsubstituted derivatives of glycylcyclines
IL182277A0 (en) Method and intermediates for the preparation of derivatives of n-(1-benzhydryl-azetidin-3-yl)-n-phenyl-methylsulphonamide
GB0520365D0 (en) Crystal structure of CD44 and its use
EP1802560A4 (en) HALOCOMB STATINE AND METHOD FOR THE PRODUCTION THEREOF
GB0414120D0 (en) Novel processes and intermediates
GB0510501D0 (en) Display of operational instructions
GB0413527D0 (en) Isolation and purification of biochemicals
PL369353A1 (pl) Zestaw elementów budowlanych
AU2004903329A0 (en) Construction elements and methods of construction
AU2004903886A0 (en) Construction elements and methods of construction
AU2004903205A0 (en) Construction elements and methods of construction
IL181795A0 (en) Liposomal compositions of glucocorticoid and glucocorticoid derivatives