ZA200608572B - Assay for antibodies - Google Patents

Assay for antibodies Download PDF

Info

Publication number
ZA200608572B
ZA200608572B ZA200608572A ZA200608572A ZA200608572B ZA 200608572 B ZA200608572 B ZA 200608572B ZA 200608572 A ZA200608572 A ZA 200608572A ZA 200608572 A ZA200608572 A ZA 200608572A ZA 200608572 B ZA200608572 B ZA 200608572B
Authority
ZA
South Africa
Prior art keywords
antibody
interest
detectable
antibodies
capture reagent
Prior art date
Application number
ZA200608572A
Other languages
English (en)
Inventor
Anan Chuntharapai
Yu-Ju G Meng
Kyu Hee Hong
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of ZA200608572B publication Critical patent/ZA200608572B/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/686Anti-idiotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70532B7 molecules, e.g. CD80, CD86
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70578NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30 CD40 or CD95
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/715Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA200608572A 2004-04-16 2005-04-15 Assay for antibodies ZA200608572B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56319304P 2004-04-16 2004-04-16

Publications (1)

Publication Number Publication Date
ZA200608572B true ZA200608572B (en) 2008-06-25

Family

ID=35320844

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200608572A ZA200608572B (en) 2004-04-16 2005-04-15 Assay for antibodies

Country Status (12)

Country Link
US (2) US20060099662A1 (zh)
EP (1) EP1745288A2 (zh)
KR (1) KR20070012826A (zh)
CN (1) CN1997893A (zh)
AU (1) AU2005241431A1 (zh)
BR (1) BRPI0509419A (zh)
CA (1) CA2563334A1 (zh)
IL (1) IL178509A0 (zh)
MX (1) MXPA06011824A (zh)
RU (1) RU2006145450A (zh)
WO (1) WO2005108989A2 (zh)
ZA (1) ZA200608572B (zh)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002544174A (ja) * 1999-05-07 2002-12-24 ジェネンテック・インコーポレーテッド B細胞表面マーカーに結合するアンタゴニストを用いた自己免疫疾患の治療
CA2422076A1 (en) * 2000-09-18 2002-03-21 Idec Pharmaceutical Corporation Combination therapy for treatment of autoimmune diseases using b cell depleting/immunoregulatory antibody combination
LT2348051T (lt) 2003-11-05 2019-02-25 Roche Glycart Ag Cd20 antikūnai su padidintu fc receptoriaus prisijungimo giminingumu ir efektorine funkcija
KR20070057839A (ko) * 2004-08-19 2007-06-07 제넨테크, 인크. 변경된 이펙터 기능을 갖는 폴리펩티드 변이체
US20060172357A1 (en) * 2004-12-31 2006-08-03 Genentech Detecting human antibodies in non-human serum
DOP2006000029A (es) * 2005-02-07 2006-08-15 Genentech Inc Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas)
EP1870456A4 (en) * 2005-03-31 2008-08-27 Univ Osaka PROCESS FOR PREPARING AN ANTIBODY TESTED AGAINST A CELL MEMBRANE SURFACE ANTIGENEPITOPE AND TEST METHODS
KR20070122497A (ko) * 2005-04-22 2007-12-31 제넨테크, 인크. Cd20 항체로 치매 또는 알츠하이머병을 치료하는 방법
US20070161089A1 (en) * 2005-11-08 2007-07-12 Genentech, Inc. Method of Producing Pan-Specific Antibodies
WO2009032128A1 (en) * 2007-08-28 2009-03-12 Abbott Biotechnology Ltd. Compositions and methods comprising binding proteins for adalimumab
TW201014605A (en) 2008-09-16 2010-04-16 Genentech Inc Methods for treating progressive multiple sclerosis
JP5634405B2 (ja) * 2008-10-07 2014-12-03 ユィロス・パテント・アクチボラグGyros Patent AB 試料中のアナライトの検出のための半逐次アッセイ
WO2010075249A2 (en) 2008-12-22 2010-07-01 Genentech, Inc. A method for treating rheumatoid arthritis with b-cell antagonists
RU2568831C2 (ru) * 2009-07-28 2015-11-20 Шайр Хьюман Дженетик Терапиз Композиции и способы для лечения болезни гоше
AR078161A1 (es) 2009-09-11 2011-10-19 Hoffmann La Roche Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento.
WO2011100403A1 (en) 2010-02-10 2011-08-18 Immunogen, Inc Cd20 antibodies and uses thereof
CN101936991B (zh) * 2010-08-03 2013-01-09 河北科技大学 微孔板洗板机双排吸液头
CN101912854B (zh) * 2010-08-03 2013-01-09 河北科技大学 微孔板洗板机双排加液头
RU2603284C2 (ru) 2010-08-17 2016-11-27 Ф.Хоффманн-Ля Рош Аг АНТИТЕЛА ПРОТИВ IgG1 ЧЕЛОВЕКА
MX2013012284A (es) 2011-04-29 2013-11-21 Bristol Myers Squibb Co Regimenes de elevacion de dosis del anticuerpo de proteina 10 inducible por interferon gamma (ip-10).
EP2920210B1 (en) * 2012-11-19 2017-08-30 Baliopharm AG Recombinant bispecific antibody binding to cd20 and cd95
CN105683755B (zh) * 2013-11-05 2019-08-13 豪夫迈·罗氏有限公司 陷阱分子和检测分子的用途及其相关试剂盒和组合物
KR20210138588A (ko) * 2019-03-08 2021-11-19 제넨테크, 인크. 세포외 소포 상에서 막 관련 단백질을 검출하고 정량하기 위한 방법
CN114935654B (zh) * 2022-05-26 2023-09-01 四川大学华西医院 检测样本cd72蛋白的试剂或诊断装置在制备检测脓毒症的试剂或试剂盒中的应用

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE337223B (zh) * 1967-05-23 1971-08-02 Pharmacia Ab
US3720760A (en) * 1968-09-06 1973-03-13 Pharmacia Ab Method for determining the presence of reagin-immunoglobulins(reagin-ig)directed against certain allergens,in aqueous samples
FR2046920B1 (zh) * 1969-06-19 1974-05-03 Citizen Watch Co Ltd
US3691016A (en) * 1970-04-17 1972-09-12 Monsanto Co Process for the preparation of insoluble enzymes
US3940475A (en) * 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
CA1023287A (en) * 1972-12-08 1977-12-27 Boehringer Mannheim G.M.B.H. Process for the preparation of carrier-bound proteins
US4195128A (en) * 1976-05-03 1980-03-25 Bayer Aktiengesellschaft Polymeric carrier bound ligands
US4330440A (en) * 1977-02-08 1982-05-18 Development Finance Corporation Of New Zealand Activated matrix and method of activation
CA1093991A (en) * 1977-02-17 1981-01-20 Hideo Hirohara Enzyme immobilization with pullulan gel
US4229537A (en) * 1978-02-09 1980-10-21 New York University Preparation of trichloro-s-triazine activated supports for coupling ligands
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4699880A (en) * 1984-09-25 1987-10-13 Immunomedics, Inc. Method of producing monoclonal anti-idiotype antibody
US4737456A (en) * 1985-05-09 1988-04-12 Syntex (U.S.A.) Inc. Reducing interference in ligand-receptor binding assays
IL85035A0 (en) * 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
JPH04507285A (ja) * 1988-12-09 1992-12-17 セントコー・インコーポレーテッド 抗イディオトープ免疫検定法
IE922437A1 (en) * 1991-07-25 1993-01-27 Idec Pharma Corp Recombinant antibodies for human therapy
US5736137A (en) * 1992-11-13 1998-04-07 Idec Pharmaceuticals Corporation Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
US5595721A (en) * 1993-09-16 1997-01-21 Coulter Pharmaceutical, Inc. Radioimmunotherapy of lymphoma using anti-CD20
CU22615A1 (es) * 1994-06-30 2000-02-10 Centro Inmunologia Molecular Procedimiento de obtención de anticuerpos monoclonales murinos menos inmunogénicos. anticuerpos monoclonales obtenidos
US6528625B1 (en) * 1996-10-28 2003-03-04 Millennium Pharmaceuticals, Inc. Anti-CCR5 antibodies and kits comprising same
US6528624B1 (en) * 1998-04-02 2003-03-04 Genentech, Inc. Polypeptide variants
US6696550B2 (en) * 1998-07-23 2004-02-24 Millennium Pharmaceuticals, Inc. Humanized anti-CCR2 antibodies and methods of use therefor
US6610834B1 (en) * 1998-11-18 2003-08-26 Peter I. Lobo Human IgM antibodies to chemokine receptors
US6329159B1 (en) * 1999-03-11 2001-12-11 Millennium Pharmaceuticals, Inc. Anti-GPR-9-6 antibodies and methods of identifying agents which modulate GPR-9-6 function
US6692922B2 (en) * 2000-08-15 2004-02-17 The Board Of Trustees Of The Leland Stanford Junior University Method for identifying agents which modulate chemokine “MEC”-induced functions of CCR3
US7413866B2 (en) * 2001-11-30 2008-08-19 Chemocentryx, Inc. Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
AU2003210802B2 (en) * 2002-02-05 2009-09-10 Genentech Inc. Protein purification
AU2003220384B2 (en) * 2002-03-18 2007-05-10 Merck Sharp & Dohme Corp. Combination treatments for chemokine-mediated diseases
US6938142B2 (en) * 2002-08-28 2005-08-30 Micron Technology, Inc. Multi-bank memory accesses using posted writes
PL218660B1 (pl) * 2002-10-17 2015-01-30 Genmab As Izolowane ludzkie przeciwciało monoklonalne wiążące ludzki CD20, związane z tym przeciwciałem transfektoma, komórka gospodarza, transgeniczne zwierzę lub roślina, kompozycja, immunokoniugat, cząsteczka bispecyficzna, wektor ekspresyjny, kompozycja farmaceutyczna, zastosowanie medyczne, zestaw oraz przeciwciało antyidiotypowe i jego zastosowanie

Also Published As

Publication number Publication date
WO2005108989A3 (en) 2006-06-01
US20070015228A1 (en) 2007-01-18
WO2005108989A2 (en) 2005-11-17
CN1997893A (zh) 2007-07-11
CA2563334A1 (en) 2005-11-17
AU2005241431A1 (en) 2005-11-17
IL178509A0 (en) 2007-02-11
US20080176257A9 (en) 2008-07-24
EP1745288A2 (en) 2007-01-24
US20060099662A1 (en) 2006-05-11
KR20070012826A (ko) 2007-01-29
RU2006145450A (ru) 2008-06-27
BRPI0509419A (pt) 2007-09-04
MXPA06011824A (es) 2006-12-15

Similar Documents

Publication Publication Date Title
US20060099662A1 (en) Assay for antibodies
KR101832510B1 (ko) 치료 항-ige 항체에 대해 특이적인 항체를 검출하기 위한 검정 및 아나필락시스에서의 이의 용도
KR100890873B1 (ko) 유전자 재조합 항체 및 이의 항체 단편
KR20190097094A (ko) 인간 il-15에 특이적으로 결합하는 항체 및 이의 용도
US20140127229A1 (en) Ip-10 antibody dosage escalation regimens
CN103079644A (zh) 抗tim-3抗体
KR20040044492A (ko) 사람형 cdr-이식 항체 및 이의 항체 단편
KR20230092978A (ko) 개 및 고양이 온코스타틴 m 수용체 베타에 대한 항체 및 이의 용도
US20240228649A9 (en) Crtam antibodies and methods of treating cancer
WO2022093640A1 (en) Anti-nkg2c agents and compositions and methods for making and using the same
WO2022241034A1 (en) Anti-ccr8 antibodies, antigen-binding fragments thereof, and agents and compositions and methods for making and using the same
US10100120B2 (en) Antibody which specifically binds to human CRTH2
US12006363B2 (en) Anti-tetraspanin 33 agents and compositions and methods for making and using the same
WO2017126587A1 (ja) 抗ヒトccr1モノクローナル抗体
US20240309086A1 (en) Notch4 antibodies, compositions, and methods for treating airway inflammation
US20240360228A1 (en) Anti-ccr8 antibodies, antigen-binding fragments thereof, and agents and compositions and methods for making and using the same
US20230054169A1 (en) Anti-tlr7 agents and compositions and methods for making and using the same
RU2795411C2 (ru) Моноклональные антитела к интерлейкину-31 для ветеринарного применения
WO2024020051A1 (en) Anti-cd157 antibodies, antigen-binding fragments thereof and compositions and methods for making and using the same
Foltz et al. Strategies for Screening of Biologic Therapeutics