ZA200607634B - Caspase inhibitors and uses thereof - Google Patents

Caspase inhibitors and uses thereof Download PDF

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Publication number
ZA200607634B
ZA200607634B ZA2006/07634A ZA200607634A ZA200607634B ZA 200607634 B ZA200607634 B ZA 200607634B ZA 2006/07634 A ZA2006/07634 A ZA 2006/07634A ZA 200607634 A ZA200607634 A ZA 200607634A ZA 200607634 B ZA200607634 B ZA 200607634B
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ZA
South Africa
Prior art keywords
disease
compound
formula
protecting group
carboxylic acid
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ZA2006/07634A
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English (en)
Inventor
Adam Looker
Martin Trudeau
Sharn Ramaya
Alistair Rutherford
Michael Odonnell
John R Studley
Michael Mortimore
Steven Durrant
Jean Damien Charrier
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Vertex Pharma
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Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of ZA200607634B publication Critical patent/ZA200607634B/en

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ZA2006/07634A 2004-02-27 2006-09-12 Caspase inhibitors and uses thereof ZA200607634B (en)

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CN102362867A (zh) * 2004-05-15 2012-02-29 沃泰克斯药物股份有限公司 使用ice抑制剂治疗癫痫发作
EP1778221A2 (en) * 2004-05-27 2007-05-02 Vertex Pharmaceuticals Incorporated Ice inhibitors for the treatment of autoinflammatory diseases
WO2011094426A1 (en) * 2010-01-29 2011-08-04 The United State Of America, As Represented By The Secretary, Department Of Health & Human Services Caspase inhibitors
US9956260B1 (en) 2011-07-22 2018-05-01 The J. David Gladstone Institutes Treatment of HIV-1 infection and AIDS
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WO2017079566A1 (en) 2015-11-05 2017-05-11 Conatus Pharmaceuticals, Inc. Caspase inhibitors for use in the treatment of liver cancer
JP2019500397A (ja) 2015-12-31 2019-01-10 クオナトウス ファーマシューティカルズ，インコーポレイテッド カスパーゼ阻害剤を肝疾患の治療に使用する方法
CN105853408B (zh) * 2016-04-15 2018-12-04 浙江大学 苯酰胺衍生物在制备Caspase-1抑制剂中的应用
RU2019113150A (ru) 2016-10-05 2020-11-06 Новартис Аг Комбинация композиций, содержащих агонисты fxr, предназначенная для лечения или предупреждения фиброзирующего, цирротического заболевания или нарушения
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IL177709A0 (en) 2006-12-31
NO20064344L (no) 2006-10-19
AU2005219861B2 (en) 2011-08-11
TW200540152A (en) 2005-12-16
WO2005085236A2 (en) 2005-09-15
RU2006134258A (ru) 2008-04-10
TW201217332A (en) 2012-05-01
TWI362381B (en) 2012-04-21
EP2270004A1 (en) 2011-01-05
BRPI0508102A (pt) 2007-07-17
RU2382780C2 (ru) 2010-02-27
JP2014140385A (ja) 2014-08-07
US7652153B2 (en) 2010-01-26
KR20060129069A (ko) 2006-12-14
JP2007525503A (ja) 2007-09-06
HK1099757A1 (en) 2007-08-24
AU2005219861A1 (en) 2005-09-15
NZ549665A (en) 2010-09-30
CN102161656A (zh) 2011-08-24
CN102161656B (zh) 2013-02-20
CA2557645C (en) 2013-09-24
CA2557645A1 (en) 2005-09-15
US20050233979A1 (en) 2005-10-20
WO2005085236A3 (en) 2005-10-20
NO20064351L (no) 2006-11-20
JP2011144203A (ja) 2011-07-28
HK1159614A1 (en) 2012-08-03
US20100105914A1 (en) 2010-04-29
AR047981A1 (es) 2006-03-15

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