ZA200606465B - A fluid dispenser - Google Patents
A fluid dispenser Download PDFInfo
- Publication number
- ZA200606465B ZA200606465B ZA200606465A ZA200606465A ZA200606465B ZA 200606465 B ZA200606465 B ZA 200606465B ZA 200606465 A ZA200606465 A ZA 200606465A ZA 200606465 A ZA200606465 A ZA 200606465A ZA 200606465 B ZA200606465 B ZA 200606465B
- Authority
- ZA
- South Africa
- Prior art keywords
- dispenser
- metering chamber
- appended
- section
- boundary wall
- Prior art date
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- 229960005181 morphine Drugs 0.000 description 1
- DUWWHGPELOTTOE-UHFFFAOYSA-N n-(5-chloro-2,4-dimethoxyphenyl)-3-oxobutanamide Chemical compound COC1=CC(OC)=C(NC(=O)CC(C)=O)C=C1Cl DUWWHGPELOTTOE-UHFFFAOYSA-N 0.000 description 1
- PLPRGLOFPNJOTN-UHFFFAOYSA-N narcotine Natural products COc1ccc2C(OC(=O)c2c1OC)C3Cc4c(CN3C)cc5OCOc5c4OC PLPRGLOFPNJOTN-UHFFFAOYSA-N 0.000 description 1
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- 210000001331 nose Anatomy 0.000 description 1
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- NVOYVOBDTVTBDX-PMEUIYRNSA-N oxitropium Chemical compound CC[N+]1(C)[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)C1=CC=CC=C1 NVOYVOBDTVTBDX-PMEUIYRNSA-N 0.000 description 1
- 229960000797 oxitropium Drugs 0.000 description 1
- RLANKEDHRWMNRO-UHFFFAOYSA-M oxtriphylline Chemical compound C[N+](C)(C)CCO.O=C1N(C)C(=O)N(C)C2=C1[N-]C=N2 RLANKEDHRWMNRO-UHFFFAOYSA-M 0.000 description 1
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- 150000002960 penicillins Chemical class 0.000 description 1
- XDRYMKDFEDOLFX-UHFFFAOYSA-N pentamidine Chemical compound C1=CC(C(=N)N)=CC=C1OCCCCCOC1=CC=C(C(N)=N)C=C1 XDRYMKDFEDOLFX-UHFFFAOYSA-N 0.000 description 1
- 229960004448 pentamidine Drugs 0.000 description 1
- 229960001802 phenylephrine Drugs 0.000 description 1
- SONNWYBIRXJNDC-VIFPVBQESA-N phenylephrine Chemical compound CNC[C@H](O)C1=CC=CC(O)=C1 SONNWYBIRXJNDC-VIFPVBQESA-N 0.000 description 1
- 229960000395 phenylpropanolamine Drugs 0.000 description 1
- DLNKOYKMWOXYQA-APPZFPTMSA-N phenylpropanolamine Chemical compound C[C@@H](N)[C@H](O)C1=CC=CC=C1 DLNKOYKMWOXYQA-APPZFPTMSA-N 0.000 description 1
- 229960005414 pirbuterol Drugs 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 229960004583 pranlukast Drugs 0.000 description 1
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- 229960005205 prednisolone Drugs 0.000 description 1
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
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- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- MIXMJCQRHVAJIO-TZHJZOAOSA-N qk4dys664x Chemical compound O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O MIXMJCQRHVAJIO-TZHJZOAOSA-N 0.000 description 1
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- IXTCZMJQGGONPY-XJAYAHQCSA-N rofleponide Chemical compound C1([C@@H](F)C2)=CC(=O)CC[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3O[C@@H](CCC)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O IXTCZMJQGGONPY-XJAYAHQCSA-N 0.000 description 1
- 229960002586 roflumilast Drugs 0.000 description 1
- MNDBXUUTURYVHR-UHFFFAOYSA-N roflumilast Chemical compound FC(F)OC1=CC=C(C(=O)NC=2C(=CN=CC=2Cl)Cl)C=C1OCC1CC1 MNDBXUUTURYVHR-UHFFFAOYSA-N 0.000 description 1
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- 229960005322 streptomycin Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
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- 229960000195 terbutaline Drugs 0.000 description 1
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- 150000003522 tetracyclines Chemical class 0.000 description 1
- 229940040944 tetracyclines Drugs 0.000 description 1
- 229960000278 theophylline Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000003813 thumb Anatomy 0.000 description 1
- LERNTVKEWCAPOY-DZZGSBJMSA-N tiotropium Chemical compound O([C@H]1C[C@@H]2[N+]([C@H](C1)[C@@H]1[C@H]2O1)(C)C)C(=O)C(O)(C=1SC=CC=1)C1=CC=CS1 LERNTVKEWCAPOY-DZZGSBJMSA-N 0.000 description 1
- 229940110309 tiotropium Drugs 0.000 description 1
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- 230000000699 topical effect Effects 0.000 description 1
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- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 description 1
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1042—Components or details
- B05B11/1066—Pump inlet valves
- B05B11/1067—Pump inlet valves actuated by pressure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1042—Components or details
- B05B11/1052—Actuation means
- B05B11/1056—Actuation means comprising rotatable or articulated levers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1042—Components or details
- B05B11/1066—Pump inlet valves
- B05B11/107—Gate valves; Sliding valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/109—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1095—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle with movable suction side
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/0005—Components or details
- B05B11/0037—Containers
- B05B11/0038—Inner container disposed in an outer shell or outer casing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1001—Piston pumps
Landscapes
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Devices For Dispensing Beverages (AREA)
- Loading And Unloading Of Fuel Tanks Or Ships (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0402694.4A GB0402694D0 (en) | 2004-02-06 | 2004-02-06 | A fluid dispenser |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200606465B true ZA200606465B (en) | 2008-01-30 |
Family
ID=31985820
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200606465A ZA200606465B (en) | 2004-02-06 | 2006-08-03 | A fluid dispenser |
Country Status (10)
Country | Link |
---|---|
US (1) | US20070137643A1 (de) |
EP (1) | EP1725339A1 (de) |
JP (1) | JP2007520348A (de) |
CN (1) | CN1933918A (de) |
AU (1) | AU2005210212A1 (de) |
BR (1) | BRPI0507393A (de) |
CA (1) | CA2554658A1 (de) |
GB (1) | GB0402694D0 (de) |
WO (1) | WO2005075102A1 (de) |
ZA (1) | ZA200606465B (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8132695B2 (en) * | 2006-11-11 | 2012-03-13 | Medical Instill Technologies, Inc. | Multiple dose delivery device with manually depressible actuator and one-way valve for storing and dispensing substances, and related method |
EP2077132A1 (de) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Abgabevorrichtung, Aufbewahrungsvorrichtung und Verfahren zur Abgabe einer Formulierung |
CA2732826C (en) * | 2008-09-26 | 2017-08-22 | Oriel Therapeutics, Inc. | Inhaler mechanisms with radially biased piercers and related methods |
MX2011003244A (es) | 2008-09-26 | 2011-04-28 | Oriel Therapeutics Inc | Inhaladores con discos de vias aereas con canales de vias aereas discretas y discos y metodos relacionados. |
MX2011003233A (es) | 2008-09-26 | 2011-04-28 | Oriel Therapeutics Inc | Inhaladores de polvo seco con miembros de perforacion doble y dispositivos y metodos relacionados. |
WO2010039201A2 (en) * | 2008-09-30 | 2010-04-08 | Oriel Therapeutics, Inc. | Dry powder inhalers with multi-facet surface deagglomeration chambers and related devices and methods |
WO2010039202A2 (en) * | 2008-10-01 | 2010-04-08 | Oriel Therapeutics, Inc. | Dry powder inhalers with rotating piercing mechanisms and related devices and methods |
EP2398595B1 (de) * | 2009-02-18 | 2017-11-22 | Boehringer Ingelheim International GmbH | Vorrichtung, kartusche und verfahren zum ausgeben von flüssigkeit |
US8387832B2 (en) * | 2009-03-06 | 2013-03-05 | Gojo Industries, Inc. | Dispenser housing |
EP2414560B1 (de) | 2009-03-31 | 2013-10-23 | Boehringer Ingelheim International GmbH | Verfahren zur beschichtung einer oberfläche eines bauteils |
JP5763053B2 (ja) | 2009-05-18 | 2015-08-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | アダプタ、吸入器具及びアトマイザ |
WO2011064164A1 (en) | 2009-11-25 | 2011-06-03 | Boehringer Ingelheim International Gmbh | Nebulizer |
JP5658268B2 (ja) | 2009-11-25 | 2015-01-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
USD641076S1 (en) | 2010-03-26 | 2011-07-05 | Oriel Therapeutics, Inc. | Dry powder inhaler |
USD635246S1 (en) | 2010-03-26 | 2011-03-29 | Oriel Therapeutics, Inc. | Dose disk for dry powder inhalers |
WO2011160932A1 (en) | 2010-06-24 | 2011-12-29 | Boehringer Ingelheim International Gmbh | Nebulizer |
WO2012130757A1 (de) | 2011-04-01 | 2012-10-04 | Boehringer Ingelheim International Gmbh | Medizinisches gerät mit behälter |
US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
WO2013152894A1 (de) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Zerstäuber mit kodiermitteln |
EP2835146B1 (de) | 2013-08-09 | 2020-09-30 | Boehringer Ingelheim International GmbH | Zerstäuber |
JP6643231B2 (ja) | 2013-08-09 | 2020-02-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
JP6580070B2 (ja) | 2014-05-07 | 2019-09-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 容器、ネブライザ、及び使用 |
PL3139984T3 (pl) | 2014-05-07 | 2021-11-08 | Boehringer Ingelheim International Gmbh | Nebulizator |
LT3928818T (lt) | 2014-05-07 | 2023-03-27 | Boehringer Ingelheim International Gmbh | Purkštuvas ir talpa |
WO2016090235A1 (en) | 2014-12-05 | 2016-06-09 | LifeFuels, Inc. | A system and apparatus for optimizing hydration and for the contextual dispensing of additives |
US10913647B2 (en) | 2015-06-11 | 2021-02-09 | LifeFuels, Inc. | Portable system for dispensing controlled quantities of additives into a beverage |
US10889424B1 (en) | 2019-09-14 | 2021-01-12 | LifeFuels, Inc. | Portable beverage container systems and methods for adjusting the composition of a beverage |
US10231567B2 (en) | 2015-06-11 | 2019-03-19 | LifeFuels, Inc. | System, method, and apparatus for dispensing variable quantities of additives and controlling characteristics thereof in a beverage |
EP3378569A1 (de) | 2017-03-21 | 2018-09-26 | The Procter & Gamble Company | Spendervorrichtung |
EP3450351A1 (de) * | 2017-09-01 | 2019-03-06 | The Procter & Gamble Company | Vorrichtung und verfahren zur abgabe einer abgemessenen dosis eines produktes |
DE102017124742A1 (de) * | 2017-10-23 | 2019-04-25 | Nebu-Tec Med. Produkte Eike Kern Gmbh | Automatische Medikamentendosierung bei Verneblern |
EP3489171A1 (de) | 2017-11-23 | 2019-05-29 | The Procter & Gamble Company | Kolben mit flexiblem verschluss für aerosolbehälter |
EP3513880B1 (de) | 2018-01-23 | 2021-08-25 | The Procter & Gamble Company | Abgabevorrichtung, die für schäumende produkte geeignet ist |
US11337533B1 (en) | 2018-06-08 | 2022-05-24 | Infuze, L.L.C. | Portable system for dispensing controlled quantities of additives into a beverage |
US10850914B2 (en) | 2018-11-08 | 2020-12-01 | The Procter And Gamble Company | Dip tube aerosol dispenser with upright actuator |
US11267644B2 (en) | 2018-11-08 | 2022-03-08 | The Procter And Gamble Company | Aerosol foam dispenser and methods for delivering a textured foam product |
US10981772B1 (en) | 2019-09-14 | 2021-04-20 | LifeFuels, Inc. | Portable beverage container systems and methods for adjusting the composition of a beverage |
US11903516B1 (en) | 2020-04-25 | 2024-02-20 | Cirkul, Inc. | Systems and methods for bottle apparatuses, container assemblies, and dispensing apparatuses |
WO2022016012A1 (en) | 2020-07-15 | 2022-01-20 | Cirkul, Inc. | Portable carbonating dispensers |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE68902989T2 (de) * | 1988-12-20 | 1993-04-15 | Step Soc Tech Pulverisation | Vorrichtung zum spenden einer fluessigkeit oder einer creme in tropfen kleinen volumens. |
US5085351A (en) * | 1990-11-05 | 1992-02-04 | Martin James H | Adjustable dose dispenser |
FR2674747B1 (fr) * | 1991-04-05 | 1993-07-30 | Step Soc Tech Pulverisation | Dispositif distributeur de gouttes de petit volume, notamment pour soins ophtalmologiques. |
WO1993000172A1 (fr) * | 1991-06-26 | 1993-01-07 | Valois (Societe Anonyme) | Dispositif pour projeter une dose predeterminee d'un produit fluide, et son procede de remplissage |
DE19610456B4 (de) * | 1996-03-16 | 2006-10-19 | Ing. Erich Pfeiffer Gmbh | Austragvorrichtung für Medien |
DE19622124A1 (de) * | 1996-06-01 | 1997-12-04 | Alfred Von Schuckmann | Gerät zum Aufbringen von Flüssigkeiten |
FR2781772B1 (fr) * | 1998-07-31 | 2000-10-13 | Sofab | Distributeur de produits liquides destines a etre delivres par pulverisation |
ATE325633T1 (de) * | 1999-11-08 | 2006-06-15 | Capnia Inc | Vorrichtung zur gleichzeitigen verabreichung von gasen und medikamenten |
FR2809088B1 (fr) * | 2000-05-19 | 2002-07-26 | Oreal | Embout doseur et ensemble de distribution equipe d'un tel embout |
GB0016123D0 (en) * | 2000-07-01 | 2000-08-23 | Glaxo Group Ltd | Valve for aerosol container |
JP3403702B2 (ja) * | 2000-07-03 | 2003-05-06 | 株式会社トップ | 吐出容器 |
DE10032976A1 (de) * | 2000-07-06 | 2002-01-17 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung für Medien |
US6745760B2 (en) * | 2001-05-15 | 2004-06-08 | Trudell Medical International | Medicament applicator |
WO2002094708A1 (en) * | 2001-05-23 | 2002-11-28 | Cohen, Ben, Z. | Accurate dosing pump |
DE10146960A1 (de) * | 2001-09-24 | 2003-04-17 | Schuckmann Alfred Von | Handbetätigbare Munddusche |
EP1471960B1 (de) * | 2002-01-07 | 2019-03-13 | Novartis AG | Vorrichtungen zur vernebelung von flüssigkeiten zur inhalation |
FR2834920B1 (fr) * | 2002-01-22 | 2004-04-09 | Valois Sa | Dispositif de pulverisation a actionnement lateral |
WO2004014567A1 (en) | 2002-08-06 | 2004-02-19 | Glaxo Group Limited | A dispenser |
-
2004
- 2004-02-06 GB GBGB0402694.4A patent/GB0402694D0/en not_active Ceased
-
2005
- 2005-02-04 EP EP05708243A patent/EP1725339A1/de not_active Withdrawn
- 2005-02-04 WO PCT/GB2005/000407 patent/WO2005075102A1/en active Application Filing
- 2005-02-04 CA CA002554658A patent/CA2554658A1/en not_active Abandoned
- 2005-02-04 AU AU2005210212A patent/AU2005210212A1/en not_active Abandoned
- 2005-02-04 BR BRPI0507393-6A patent/BRPI0507393A/pt not_active IP Right Cessation
- 2005-02-04 US US10/597,689 patent/US20070137643A1/en not_active Abandoned
- 2005-02-04 CN CNA2005800095068A patent/CN1933918A/zh active Pending
- 2005-02-04 JP JP2006551925A patent/JP2007520348A/ja active Pending
-
2006
- 2006-08-03 ZA ZA200606465A patent/ZA200606465B/en unknown
Also Published As
Publication number | Publication date |
---|---|
BRPI0507393A (pt) | 2007-07-10 |
US20070137643A1 (en) | 2007-06-21 |
WO2005075102A1 (en) | 2005-08-18 |
GB0402694D0 (en) | 2004-03-10 |
AU2005210212A1 (en) | 2005-08-18 |
CA2554658A1 (en) | 2005-08-18 |
EP1725339A1 (de) | 2006-11-29 |
JP2007520348A (ja) | 2007-07-26 |
CN1933918A (zh) | 2007-03-21 |
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