ZA200508579B - DNA vaccines against tumor growth and methods of use thereof - Google Patents
DNA vaccines against tumor growth and methods of use thereof Download PDFInfo
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- ZA200508579B ZA200508579B ZA200508579A ZA200508579A ZA200508579B ZA 200508579 B ZA200508579 B ZA 200508579B ZA 200508579 A ZA200508579 A ZA 200508579A ZA 200508579 A ZA200508579 A ZA 200508579A ZA 200508579 B ZA200508579 B ZA 200508579B
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- A61K39/00—Medicinal preparations containing antigens or antibodies
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- A61K39/0011—Cancer antigens
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- A61K39/001136—Cytokines
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- A61K39/0011—Cancer antigens
- A61K39/001148—Regulators of development
- A61K39/00115—Apoptosis related proteins, e.g. survivin or livin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Mycology (AREA)
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- Oncology (AREA)
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- Biochemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
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| US45700903P | 2003-03-24 | 2003-03-24 |
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| US (2) | US8716254B2 (de) |
| EP (1) | EP1622648B1 (de) |
| JP (1) | JP4616827B2 (de) |
| KR (1) | KR101199789B1 (de) |
| CN (1) | CN1791433B (de) |
| AT (1) | ATE472339T1 (de) |
| AU (1) | AU2004236636B2 (de) |
| BR (1) | BRPI0408774A (de) |
| CA (1) | CA2519953C (de) |
| DE (1) | DE602004027902D1 (de) |
| DK (1) | DK1622648T3 (de) |
| ES (1) | ES2345200T3 (de) |
| MX (1) | MXPA05010255A (de) |
| PL (1) | PL1622648T3 (de) |
| PT (1) | PT1622648E (de) |
| RU (1) | RU2343195C2 (de) |
| WO (1) | WO2004099389A2 (de) |
| ZA (1) | ZA200508579B (de) |
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| ES2560449T3 (es) | 2004-05-28 | 2016-02-19 | Oryxe | Una mezcla para administración transdérmica de compuestos de peso molecular bajo y alto |
| US20060276423A1 (en) * | 2005-04-18 | 2006-12-07 | Rachel Altura | Survivin-directed RNA interference-compositions and methods |
| US20070104689A1 (en) * | 2005-09-27 | 2007-05-10 | Merck Patent Gmbh | Compositions and methods for treating tumors presenting survivin antigens |
| KR100790377B1 (ko) * | 2006-02-15 | 2008-01-02 | 고려대학교 산학협력단 | 인터페론감마를 발현하는 살모넬라 균주를 함유하는항바이러스용 조성물 |
| CA2657217A1 (en) * | 2006-06-21 | 2007-12-27 | The Scripps Research Institute | Dna composition against tumor stromal antigen fap and methods of use thereof |
| AU2007271398B2 (en) * | 2006-07-06 | 2013-06-20 | Merck Patent Gmbh | Compositions and methods for enhancing the efficacy of IL-2 mediated immune responses |
| FR2903605A1 (fr) * | 2006-07-12 | 2008-01-18 | Sanofi Pasteur Sa | Methode d'immunisation contre les quatres serotypes de la dengue |
| FR2906724B1 (fr) * | 2006-10-04 | 2009-03-20 | Sanofi Pasteur Sa | Methode d'immunisation contre les 4 serotypes de la dengue. |
| CA2670790A1 (en) * | 2006-11-28 | 2008-06-05 | Ghc Research Development Corporation | Polypeptides comprising fas activation and nkg2d-ligand domains |
| FR2909286B1 (fr) * | 2006-12-01 | 2012-06-08 | Sanofi Pasteur | Methode d'immunisation contre les 4 serotypes de la dengue |
| US20110027303A1 (en) | 2008-03-31 | 2011-02-03 | Bioimmulance Co., Ltd. | Partial peptide of survivin presented on mhc class ii molecule and use therof |
| US9309493B2 (en) * | 2009-03-27 | 2016-04-12 | Eidgenoessische Technische Hochschule Zurich | Salmonella enterica presenting C. jejuni N-glycan or derivatives thereof |
| MX2012001999A (es) * | 2009-08-17 | 2012-02-29 | Univ California | Uso de inhibidores nkg2d para tratar enfermedades cardiovasculares y metabolicas, tal como diabetes tipo 2. |
| KR101815322B1 (ko) * | 2010-01-12 | 2018-01-05 | 서울대학교산학협력단 | 항암 펩타이드 서열 |
| WO2011161244A1 (en) * | 2010-06-25 | 2011-12-29 | Vaccibody As | Homodimeric protein constructs |
| CN102210862B (zh) * | 2011-06-01 | 2013-06-12 | 中国人民解放军南京军区福州总医院 | 基于Livin的免疫刺激复合物及其制备方法和应用 |
| CN113684185A (zh) * | 2013-02-26 | 2021-11-23 | 纪念斯隆-凯特琳癌症中心 | 用于免疫疗法的组合物和方法 |
| KR20230062674A (ko) * | 2013-03-15 | 2023-05-09 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | 암 백신 및 이를 이용한 치료 방법 |
| EP2981284A1 (de) * | 2013-04-05 | 2016-02-10 | Kyushu University National University Corporation | Dna-impfstoff gegen tumore |
| WO2015001082A1 (en) * | 2013-07-05 | 2015-01-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Novel alternative splice transcripts for mhc class i related chain alpha (mica) and uses thereof |
| AU2015229009B2 (en) * | 2014-03-14 | 2019-08-22 | Dana-Farber Cancer Institute, Inc. | Vaccine compositions and methods for restoring NKG2D pathway function against cancers |
| WO2016033532A1 (en) * | 2014-08-29 | 2016-03-03 | The Regents Of The University Of California | Vaccine for livestock production systems |
| US10414810B2 (en) | 2015-05-07 | 2019-09-17 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Double mutant survivin vaccine |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11260018B2 (en) | 2015-09-17 | 2022-03-01 | Jrx Biotechnology, Inc. | Approaches for improving skin hydration and moisturization |
| RU2020124191A (ru) | 2015-10-01 | 2020-08-27 | Потенза Терапевтикс, Инк. | Анти-tigit антиген-связывающие белки и способы их применения |
| CN110691844B (zh) * | 2017-02-07 | 2023-09-08 | 新加坡科技研究局 | 从多能干细胞产生模拟的先天免疫细胞的方法和试剂盒 |
| JOP20190203A1 (ar) | 2017-03-30 | 2019-09-03 | Potenza Therapeutics Inc | بروتينات رابطة لمولد ضد مضادة لـ tigit وطرق استخدامها |
| CN110448689A (zh) * | 2019-08-06 | 2019-11-15 | 太仓美诺恒康生物技术有限公司 | mRNA疫苗及其试剂盒、应用 |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| AU2022208435A1 (en) | 2021-01-18 | 2023-08-10 | Conserv Bioscience Limited | Coronavirus immunogenic compositions, methods and uses thereof |
| RU2770490C1 (ru) * | 2021-07-14 | 2022-04-18 | Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр "Красноярский научный центр Сибирского отделения Российской академии наук" | Рекомбинантная плазмидная ДНК pET19b-Surv-OL, обеспечивающая синтез гибридного белка сурвивин-обелин (Surv-OL) и гибридный белок, связываемый анти-сурвивин антителами и обладающий биолюминесцентной активностью |
| CN116077534A (zh) * | 2023-01-31 | 2023-05-09 | 大连工业大学 | 一种凝结芽孢杆菌的应用 |
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| US3993223A (en) * | 1974-07-25 | 1976-11-23 | American Home Products Corporation | Dispensing container |
| US5733760A (en) * | 1994-08-05 | 1998-03-31 | Virus Research Institute | Salmonella vectors encoding truncated pag fusion protein, method of making, and uses thereof |
| US6190657B1 (en) * | 1995-06-07 | 2001-02-20 | Yale University | Vectors for the diagnosis and treatment of solid tumors including melanoma |
| ATE414149T1 (de) * | 1996-11-20 | 2008-11-15 | Univ Yale | Survivin, ein protein das zelluläre apoptosis hemmt, und dessen modulation |
| AU737717B2 (en) * | 1997-08-13 | 2001-08-30 | Uab Research Foundation, The | Vaccination by topical application of genetic vectors |
| WO1999031241A1 (en) * | 1997-12-17 | 1999-06-24 | Immunex Corporation | Cell surface glycoproteins associated with human b cell lymphomas - ulbp, dna and polypeptides |
| US20030215803A1 (en) * | 2000-12-07 | 2003-11-20 | Garcia Pablo Dominguez | Human genes and gene expression products isolated from human prostate |
| AU4990999A (en) * | 1998-07-14 | 2000-02-07 | Jenner Biotherapies, Inc. | Survivin, and peptides thereof, as an anti-cancer vaccine |
| US6472172B1 (en) * | 1998-07-31 | 2002-10-29 | Schering Aktiengesellschaft | DNA encoding a novel human inhibitor-of-apoptosis protein |
| US6838283B2 (en) * | 1998-09-29 | 2005-01-04 | Isis Pharmaceuticals Inc. | Antisense modulation of survivin expression |
| US6335194B1 (en) * | 1998-09-29 | 2002-01-01 | Isis Pharmaceuticals, Inc. | Antisense modulation of survivin expression |
| IT1303683B1 (it) * | 1998-10-30 | 2001-02-23 | Menarini Ricerche Spa | Composizione farmaceutiche ad azione antitumorale contenente dnacodificante per frammenti di una proteina antigenica. |
| US6413768B1 (en) * | 1998-12-02 | 2002-07-02 | University Of Maryland | Expression plasmids |
| AU765160B2 (en) * | 1998-12-18 | 2003-09-11 | Symrise Gmbh & Co. Kg | Encapsulated flavour and/or fragrance preparations |
| WO2002002622A2 (en) * | 2000-06-29 | 2002-01-10 | The Salk Institute For Biological Studies | Crystal structure of survivin |
| EP1256354A1 (de) * | 2001-05-11 | 2002-11-13 | Schering Corporation | Verfahren zur Behandlung von Krebs |
| EP1507540A4 (de) * | 2001-10-10 | 2006-12-06 | Centocor Inc | Nukleinsäureimpfstoffe unter verwendung von tumorantigen-kodierenden nukleinsäuren mit einer cytokinadjuvans-kodierenden nukleinsäure |
| EP2301573A1 (de) * | 2002-10-01 | 2011-03-30 | Novartis Vaccines and Diagnostics, Inc. | Zusammensetzungen gegen Krebs und Infektionskrankheiten und Anwendungsverfahren dafür |
| AU2003300680A1 (en) * | 2002-12-10 | 2004-07-09 | Centre National De La Recherche Scientifique Cnrs | Thap proteins as nuclear receptors for chemokines and roles in transcriptional regulation, cell proliferation and cell differentiation |
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- 2004-03-24 PL PL04749425T patent/PL1622648T3/pl unknown
- 2004-03-24 AT AT04749425T patent/ATE472339T1/de active
- 2004-03-24 BR BRPI0408774-7A patent/BRPI0408774A/pt not_active Application Discontinuation
- 2004-03-24 EP EP04749425A patent/EP1622648B1/de not_active Expired - Lifetime
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- 2004-03-24 JP JP2006507511A patent/JP4616827B2/ja not_active Expired - Fee Related
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- 2004-03-24 DE DE602004027902T patent/DE602004027902D1/de not_active Expired - Lifetime
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Also Published As
| Publication number | Publication date |
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| RU2005132578A (ru) | 2006-05-10 |
| AU2004236636B2 (en) | 2010-02-04 |
| WO2004099389A2 (en) | 2004-11-18 |
| US8716254B2 (en) | 2014-05-06 |
| KR20050121694A (ko) | 2005-12-27 |
| EP1622648A4 (de) | 2007-02-14 |
| AU2004236636A1 (en) | 2004-11-18 |
| BRPI0408774A (pt) | 2006-03-28 |
| US20140322249A1 (en) | 2014-10-30 |
| KR101199789B1 (ko) | 2012-11-09 |
| CA2519953A1 (en) | 2004-11-18 |
| CN1791433A (zh) | 2006-06-21 |
| EP1622648B1 (de) | 2010-06-30 |
| JP4616827B2 (ja) | 2011-01-19 |
| PT1622648E (pt) | 2010-08-31 |
| EP1622648A2 (de) | 2006-02-08 |
| JP2006523217A (ja) | 2006-10-12 |
| DE602004027902D1 (de) | 2010-08-12 |
| ATE472339T1 (de) | 2010-07-15 |
| ES2345200T3 (es) | 2010-09-17 |
| CA2519953C (en) | 2016-01-05 |
| DK1622648T3 (da) | 2010-09-06 |
| US9655815B2 (en) | 2017-05-23 |
| US20040192631A1 (en) | 2004-09-30 |
| RU2343195C2 (ru) | 2009-01-10 |
| PL1622648T3 (pl) | 2010-11-30 |
| WO2004099389A3 (en) | 2005-09-29 |
| CN1791433B (zh) | 2010-05-26 |
| MXPA05010255A (es) | 2005-12-14 |
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