ZA200505077B - Atropisomers of 3-substituted-4-arylquinolin-2-onederivatives - Google Patents
Atropisomers of 3-substituted-4-arylquinolin-2-onederivatives Download PDFInfo
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- ZA200505077B ZA200505077B ZA200505077A ZA200505077A ZA200505077B ZA 200505077 B ZA200505077 B ZA 200505077B ZA 200505077 A ZA200505077 A ZA 200505077A ZA 200505077 A ZA200505077 A ZA 200505077A ZA 200505077 B ZA200505077 B ZA 200505077B
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- South Africa
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- compound
- atropisomer
- composition
- chloro
- trifluoromethyl
- Prior art date
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Classifications
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- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Anti-Oxidant Or Stabilizer Compositions (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43616002P | 2002-12-23 | 2002-12-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200505077B true ZA200505077B (en) | 2006-09-27 |
Family
ID=32682352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200505077A ZA200505077B (en) | 2002-12-23 | 2005-06-22 | Atropisomers of 3-substituted-4-arylquinolin-2-onederivatives |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6939968B2 (pl) |
| EP (1) | EP1575589B1 (pl) |
| JP (1) | JP2006512378A (pl) |
| KR (1) | KR20050102081A (pl) |
| CN (1) | CN1750821A (pl) |
| AT (1) | ATE472328T1 (pl) |
| AU (1) | AU2003300425A1 (pl) |
| BR (1) | BR0317679A (pl) |
| CZ (1) | CZ2005407A3 (pl) |
| DE (1) | DE60333226D1 (pl) |
| IL (1) | IL169294A (pl) |
| MX (1) | MXPA05006814A (pl) |
| NO (1) | NO20053078L (pl) |
| NZ (1) | NZ541237A (pl) |
| PL (1) | PL377492A1 (pl) |
| RU (1) | RU2352563C2 (pl) |
| TR (1) | TR200502440T2 (pl) |
| WO (1) | WO2004058260A1 (pl) |
| ZA (1) | ZA200505077B (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101679243B (zh) * | 2007-04-09 | 2012-09-26 | 第一三共株式会社 | 吡咯衍生物的阻转异构体 |
| EP2456440B1 (en) * | 2009-07-22 | 2015-08-19 | Merck Sharp & Dohme Corp. | Quinolinone pde2 inhibitors |
| HUE041725T2 (hu) | 2013-04-10 | 2019-05-28 | Daiichi Sankyo Co Ltd | (S)-1-(2-hidroxietil)-4-metil-N-[4-(metilszulfonil)fenil]-5-[2-(trifluormetil)fenil]-1H-pirrol-3-karboxamid kristálya |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW504504B (en) | 1996-11-26 | 2002-10-01 | Bristol Myers Squibb Co | 4-aryl-3-hydroxyquinolin-2-one derivatives as ion channel modulators |
| NZ336628A (en) * | 1997-02-28 | 2001-03-30 | Pfizer Prod Inc | Atropisomers of 3-aryl-4(3H)-quinazolinones and their use as AMPA-receptor antagonists |
| RU2240998C2 (ru) * | 1998-12-04 | 2004-11-27 | Бристол-Маерс Сквибб Компани | Производные 3-замещенного 4-арилхинолин-2-она в качестве модуляторов калиевых каналов |
| TW562799B (en) * | 1999-12-01 | 2003-11-21 | Bristol Myers Squibb Co | Preparation of 3-substituted-4-arylquinolin-2-one derivatives |
| AU2002246677B2 (en) * | 2000-12-20 | 2006-11-16 | Merck Sharp & Dohme Corp. | (Halo-Benzo Carbonyl)Heterocyclo Fused Phenyl p38 Kinase Inhibiting Agents |
-
2003
- 2003-12-17 US US10/739,449 patent/US6939968B2/en not_active Expired - Fee Related
- 2003-12-18 CZ CZ2005407A patent/CZ2005407A3/cs unknown
- 2003-12-18 AT AT03814399T patent/ATE472328T1/de not_active IP Right Cessation
- 2003-12-18 WO PCT/US2003/041548 patent/WO2004058260A1/en active Application Filing
- 2003-12-18 PL PL377492A patent/PL377492A1/pl not_active Application Discontinuation
- 2003-12-18 BR BR0317679-7A patent/BR0317679A/pt not_active IP Right Cessation
- 2003-12-18 KR KR1020057011916A patent/KR20050102081A/ko not_active Application Discontinuation
- 2003-12-18 MX MXPA05006814A patent/MXPA05006814A/es active IP Right Grant
- 2003-12-18 DE DE60333226T patent/DE60333226D1/de not_active Expired - Lifetime
- 2003-12-18 RU RU2005123046/04A patent/RU2352563C2/ru not_active IP Right Cessation
- 2003-12-18 EP EP03814399A patent/EP1575589B1/en not_active Expired - Lifetime
- 2003-12-18 TR TR2005/02440T patent/TR200502440T2/xx unknown
- 2003-12-18 CN CNA2003801098331A patent/CN1750821A/zh active Pending
- 2003-12-18 JP JP2004562595A patent/JP2006512378A/ja active Pending
- 2003-12-18 AU AU2003300425A patent/AU2003300425A1/en not_active Abandoned
- 2003-12-18 NZ NZ541237A patent/NZ541237A/en unknown
-
2005
- 2005-06-20 IL IL169294A patent/IL169294A/en not_active IP Right Cessation
- 2005-06-22 ZA ZA200505077A patent/ZA200505077B/en unknown
- 2005-06-23 NO NO20053078A patent/NO20053078L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE60333226D1 (de) | 2010-08-12 |
| US20040147749A1 (en) | 2004-07-29 |
| CZ2005407A3 (cs) | 2005-10-12 |
| AU2003300425A1 (en) | 2004-07-22 |
| MXPA05006814A (es) | 2005-09-08 |
| TR200502440T2 (tr) | 2005-10-21 |
| NO20053078D0 (no) | 2005-06-23 |
| IL169294A (en) | 2010-11-30 |
| BR0317679A (pt) | 2005-11-29 |
| EP1575589A4 (en) | 2008-05-21 |
| NO20053078L (no) | 2005-08-29 |
| US6939968B2 (en) | 2005-09-06 |
| JP2006512378A (ja) | 2006-04-13 |
| RU2352563C2 (ru) | 2009-04-20 |
| KR20050102081A (ko) | 2005-10-25 |
| NZ541237A (en) | 2008-09-26 |
| ATE472328T1 (de) | 2010-07-15 |
| RU2005123046A (ru) | 2006-01-20 |
| WO2004058260A1 (en) | 2004-07-15 |
| EP1575589A1 (en) | 2005-09-21 |
| EP1575589B1 (en) | 2010-06-30 |
| CN1750821A (zh) | 2006-03-22 |
| PL377492A1 (pl) | 2006-02-06 |
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