ZA200409549B - Methods and dosage forms for controlled delivery of oxycodone - Google Patents
Methods and dosage forms for controlled delivery of oxycodone Download PDFInfo
- Publication number
- ZA200409549B ZA200409549B ZA200409549A ZA200409549A ZA200409549B ZA 200409549 B ZA200409549 B ZA 200409549B ZA 200409549 A ZA200409549 A ZA 200409549A ZA 200409549 A ZA200409549 A ZA 200409549A ZA 200409549 B ZA200409549 B ZA 200409549B
- Authority
- ZA
- South Africa
- Prior art keywords
- dosage form
- oxycodone
- administration
- core
- release
- Prior art date
Links
- 239000002552 dosage form Substances 0.000 title claims description 141
- BRUQQQPBMZOVGD-XFKAJCMBSA-N Oxycodone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(OC)C2=C5[C@@]13CCN4C BRUQQQPBMZOVGD-XFKAJCMBSA-N 0.000 title claims description 127
- 229960002085 oxycodone Drugs 0.000 title claims description 115
- 238000000034 method Methods 0.000 title claims description 25
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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ZA200409549A ZA200409549B (en) | 2002-04-29 | 2004-11-25 | Methods and dosage forms for controlled delivery of oxycodone |
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US (1) | US20040010000A1 (xx) |
EP (1) | EP1499291B1 (xx) |
JP (1) | JP2005525405A (xx) |
CN (1) | CN1665482A (xx) |
AR (1) | AR039491A1 (xx) |
AT (1) | ATE419830T1 (xx) |
AU (1) | AU2003234216A1 (xx) |
BR (1) | BR0309620A (xx) |
CA (1) | CA2483655A1 (xx) |
DE (1) | DE60325715D1 (xx) |
EC (1) | ECSP045451A (xx) |
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HK (1) | HK1072558A1 (xx) |
IL (1) | IL164911A0 (xx) |
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NZ (1) | NZ536252A (xx) |
PE (1) | PE20031017A1 (xx) |
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UY (1) | UY27789A1 (xx) |
WO (1) | WO2003092648A1 (xx) |
ZA (1) | ZA200409549B (xx) |
Families Citing this family (67)
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UA81224C2 (uk) * | 2001-05-02 | 2007-12-25 | Euro Celtic S A | Дозована форма оксикодону та її застосування |
US20110104214A1 (en) | 2004-04-15 | 2011-05-05 | Purdue Pharma L.P. | Once-a-day oxycodone formulations |
EP2957281A1 (en) | 2001-09-21 | 2015-12-23 | Egalet Ltd. | Polymer release system |
US20040253310A1 (en) | 2001-09-21 | 2004-12-16 | Gina Fischer | Morphine polymer release system |
US20050106249A1 (en) * | 2002-04-29 | 2005-05-19 | Stephen Hwang | Once-a-day, oral, controlled-release, oxycodone dosage forms |
BR0304960A (pt) * | 2002-05-31 | 2005-01-04 | Alza Corp | Formas de dosagem e composições para liberação osmótica de dosagens variáveis de oxicodona |
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
WO2004084868A1 (en) | 2003-03-26 | 2004-10-07 | Egalet A/S | Morphine controlled release system |
DE102005005446A1 (de) * | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
DE10336400A1 (de) * | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
DE102004032051A1 (de) * | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
DE102004020220A1 (de) * | 2004-04-22 | 2005-11-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
US8075872B2 (en) * | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
EP1677798A2 (en) * | 2003-10-29 | 2006-07-12 | Alza Corporation | Once-a-day, oral, controlled-release, oxycodone dosage forms |
TWI365880B (en) | 2004-03-30 | 2012-06-11 | Euro Celtique Sa | Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone and oxycodone hydrochloride composition,pharmaceutical dosage form,sustained release oeal dosage form and pharmaceutically acceptable package having less than 25 pp |
DK1765292T3 (en) | 2004-06-12 | 2018-01-02 | Collegium Pharmaceutical Inc | ABUSE PREVENTIONAL PHARMACEUTICAL FORMULATIONS |
DE102004032103A1 (de) * | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
US8541026B2 (en) | 2004-09-24 | 2013-09-24 | Abbvie Inc. | Sustained release formulations of opioid and nonopioid analgesics |
DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
PL116330U1 (en) * | 2005-10-31 | 2007-04-02 | Alza Corp | Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation |
EP1954514B1 (en) * | 2005-11-23 | 2013-07-17 | Valmet Automotive Oy | Convertible top having overcenter linkage |
SA07280459B1 (ar) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
DE102007011485A1 (de) * | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
CA2687192C (en) | 2007-06-04 | 2015-11-24 | Egalet A/S | Controlled release pharmaceutical compositions for prolonged effect |
US20090030072A1 (en) | 2007-07-03 | 2009-01-29 | Sucampo Ag | Pharmaceutical combination of opioid and prostaglandin compound |
WO2009092601A1 (en) | 2008-01-25 | 2009-07-30 | Grünenthal GmbH | Pharmaceutical dosage form |
JP2011511782A (ja) | 2008-02-12 | 2011-04-14 | アボット・ラボラトリーズ | 長期放出性ヒドロコドンアセトアミノフェンならびにその関連方法および用途 |
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- 2003-04-25 JP JP2004500833A patent/JP2005525405A/ja not_active Withdrawn
- 2003-04-25 PL PL03373031A patent/PL373031A1/xx not_active Application Discontinuation
- 2003-04-25 US US10/423,454 patent/US20040010000A1/en not_active Abandoned
- 2003-04-25 CA CA002483655A patent/CA2483655A1/en not_active Abandoned
- 2003-04-25 RU RU2004134594/15A patent/RU2004134594A/ru not_active Application Discontinuation
- 2003-04-25 NZ NZ536252A patent/NZ536252A/en unknown
- 2003-04-25 CN CN038154773A patent/CN1665482A/zh active Pending
- 2003-04-25 AU AU2003234216A patent/AU2003234216A1/en not_active Abandoned
- 2003-04-25 EP EP03728526A patent/EP1499291B1/en not_active Expired - Lifetime
- 2003-04-25 BR BR0309620-3A patent/BR0309620A/pt not_active IP Right Cessation
- 2003-04-25 DE DE60325715T patent/DE60325715D1/de not_active Expired - Lifetime
- 2003-04-25 AT AT03728526T patent/ATE419830T1/de not_active IP Right Cessation
- 2003-04-25 WO PCT/US2003/012781 patent/WO2003092648A1/en active Application Filing
- 2003-04-25 MX MXPA04010769A patent/MXPA04010769A/es unknown
- 2003-04-25 ES ES03728526T patent/ES2320435T3/es not_active Expired - Lifetime
- 2003-04-28 TW TW092109908A patent/TW200404010A/zh unknown
- 2003-04-29 UY UY27789A patent/UY27789A1/es not_active Application Discontinuation
- 2003-04-29 PE PE2003000425A patent/PE20031017A1/es not_active Application Discontinuation
- 2003-04-29 AR ARP030101492A patent/AR039491A1/es not_active Application Discontinuation
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2004
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- 2004-11-25 ZA ZA200409549A patent/ZA200409549B/en unknown
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2005
- 2005-06-28 HK HK05105361.5A patent/HK1072558A1/xx not_active IP Right Cessation
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AU2003234216A1 (en) | 2003-11-17 |
EP1499291A1 (en) | 2005-01-26 |
CA2483655A1 (en) | 2003-11-13 |
TW200404010A (en) | 2004-03-16 |
NZ536252A (en) | 2007-06-29 |
NO20045117L (no) | 2005-01-14 |
DE60325715D1 (de) | 2009-02-26 |
BR0309620A (pt) | 2005-03-15 |
PE20031017A1 (es) | 2003-11-29 |
AR039491A1 (es) | 2005-02-23 |
HK1072558A1 (en) | 2005-09-02 |
WO2003092648A1 (en) | 2003-11-13 |
IL164911A0 (en) | 2005-12-18 |
PL373031A1 (en) | 2005-08-08 |
ECSP045451A (es) | 2005-01-28 |
RU2004134594A (ru) | 2005-06-27 |
ATE419830T1 (de) | 2009-01-15 |
MXPA04010769A (es) | 2005-07-05 |
UY27789A1 (es) | 2003-08-29 |
JP2005525405A (ja) | 2005-08-25 |
US20040010000A1 (en) | 2004-01-15 |
CN1665482A (zh) | 2005-09-07 |
ES2320435T3 (es) | 2009-05-22 |
EP1499291B1 (en) | 2009-01-07 |
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