ZA200409237B - Immediate release pharmaceutical formulation. - Google Patents
Immediate release pharmaceutical formulation. Download PDFInfo
- Publication number
- ZA200409237B ZA200409237B ZA200409237A ZA200409237A ZA200409237B ZA 200409237 B ZA200409237 B ZA 200409237B ZA 200409237 A ZA200409237 A ZA 200409237A ZA 200409237 A ZA200409237 A ZA 200409237A ZA 200409237 B ZA200409237 B ZA 200409237B
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- ZA
- South Africa
- Prior art keywords
- formulation
- aze
- pab
- acid
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- 239000012729 immediate-release (IR) formulation Substances 0.000 title claims description 31
- 239000008194 pharmaceutical composition Substances 0.000 title claims description 12
- 239000000203 mixture Substances 0.000 claims description 102
- 238000009472 formulation Methods 0.000 claims description 86
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- 229940045902 sodium stearyl fumarate Drugs 0.000 description 1
- 239000007909 solid dosage form Substances 0.000 description 1
- 238000000371 solid-state nuclear magnetic resonance spectroscopy Methods 0.000 description 1
- 229940075554 sorbate Drugs 0.000 description 1
- 229960002920 sorbitol Drugs 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 229940071138 stearyl fumarate Drugs 0.000 description 1
- 238000011146 sterile filtration Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000003460 sulfonic acids Chemical class 0.000 description 1
- 239000001117 sulphuric acid Substances 0.000 description 1
- 235000011149 sulphuric acid Nutrition 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000001839 systemic circulation Effects 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 229960001367 tartaric acid Drugs 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000002537 thrombolytic effect Effects 0.000 description 1
- 229960005001 ticlopidine Drugs 0.000 description 1
- PHWBOXQYWZNQIN-UHFFFAOYSA-N ticlopidine Chemical compound ClC1=CC=CC=C1CN1CC(C=CS2)=C2CC1 PHWBOXQYWZNQIN-UHFFFAOYSA-N 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 238000007631 vascular surgery Methods 0.000 description 1
- 238000005550 wet granulation Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0201658A SE0201658D0 (sv) | 2002-05-31 | 2002-05-31 | Immediate release pharmaceutical formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200409237B true ZA200409237B (en) | 2005-07-14 |
Family
ID=20288036
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200409237A ZA200409237B (en) | 2002-05-31 | 2004-11-17 | Immediate release pharmaceutical formulation. |
Country Status (24)
Country | Link |
---|---|
US (1) | US20060014734A1 (uk) |
EP (1) | EP1513496A1 (uk) |
JP (2) | JP4537197B2 (uk) |
KR (1) | KR20050010016A (uk) |
CN (1) | CN1655760A (uk) |
AR (1) | AR039935A1 (uk) |
AU (2) | AU2003241239B2 (uk) |
BR (1) | BR0311363A (uk) |
CA (1) | CA2485533A1 (uk) |
CL (1) | CL2008003324A1 (uk) |
IL (1) | IL165069A0 (uk) |
IS (1) | IS7582A (uk) |
MX (1) | MXPA04011943A (uk) |
NO (1) | NO20044810L (uk) |
NZ (1) | NZ536739A (uk) |
PL (1) | PL373908A1 (uk) |
RU (2) | RU2351314C2 (uk) |
SA (1) | SA03240403B1 (uk) |
SE (1) | SE0201658D0 (uk) |
SG (1) | SG172473A1 (uk) |
TW (2) | TWI311555B (uk) |
UA (1) | UA82191C2 (uk) |
WO (1) | WO2003101423A1 (uk) |
ZA (1) | ZA200409237B (uk) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR035216A1 (es) | 2000-12-01 | 2004-05-05 | Astrazeneca Ab | Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios |
AR034517A1 (es) | 2001-06-21 | 2004-02-25 | Astrazeneca Ab | Formulacion farmaceutica |
SE0201659D0 (sv) | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | Modified release pharmaceutical formulation |
SE0201661D0 (sv) * | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | New salts |
US7781424B2 (en) * | 2003-05-27 | 2010-08-24 | Astrazeneca Ab | Modified release pharmaceutical formulation |
EA200900571A1 (ru) * | 2006-10-20 | 2009-12-30 | Айкос Корпорейшн | Композиции chk1 ингибиторов |
TW200827336A (en) | 2006-12-06 | 2008-07-01 | Astrazeneca Ab | New crystalline forms |
TW200900033A (en) * | 2007-06-21 | 2009-01-01 | Wen-Qing Li | Automatic brewing machine |
US20090061000A1 (en) * | 2007-08-31 | 2009-03-05 | Astrazeneca Ab | Pharmaceutical formulation use 030 |
US8977382B2 (en) * | 2012-05-11 | 2015-03-10 | D.P. Technology Corp. | Automatic method for milling complex channel-shaped cavities |
US9927801B2 (en) | 2012-05-11 | 2018-03-27 | D.P. Technology Corp. | Automatic method for milling complex channel-shaped cavities via coupling flank-milling positions |
CN102827053A (zh) * | 2012-09-20 | 2012-12-19 | 天津嘉宏科技有限公司 | 芳族脒衍生物,其制备方法及作为药物的用途 |
MA40281B1 (fr) | 2014-06-03 | 2018-11-30 | Idorsia Pharmaceuticals Ltd | Composés de pyrazole et leur utilisation en tant qu' agents de blocage des canaux calciques de type t |
JP6500092B2 (ja) | 2014-09-15 | 2019-04-10 | イドーシア ファーマシューティカルズ リミテッドIdorsia Pharmaceuticals Ltd | T型カルシウムチャンネルブロッカーとしてのトリアゾール化合物 |
HRP20220463T1 (hr) | 2016-12-16 | 2022-05-27 | Idorsia Pharmaceuticals Ltd | Farmaceutska kombinacija koja sadrži blokator kalcijevih kanala t-tipa |
MA47409A (fr) | 2017-02-06 | 2019-12-11 | Idorsia Pharmaceuticals Ltd | Nouveau procédé de synthèse de 1-aryl-1-trifluorométhylcyclopropanes |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5252566A (en) * | 1991-11-12 | 1993-10-12 | Eli Lilly And Company | Antithrombotic agents |
SA96170106A (ar) * | 1995-07-06 | 2005-12-03 | أسترا أكتيبولاج | مشتقات حامض أميني جديدة |
SE9601556D0 (sv) * | 1996-04-24 | 1996-04-24 | Astra Ab | New pharmaceutical formulation of a thrombin inhibitor for parenteral use |
AU3496297A (en) * | 1996-06-25 | 1998-01-14 | Eli Lilly And Company | Anticoagulant agents |
SE9704401D0 (sv) * | 1997-11-28 | 1997-11-28 | Astra Ab | Matrix pellets for greasy, oily or sticky drug substances |
SE9802973D0 (sv) * | 1998-09-03 | 1998-09-03 | Astra Ab | Immediate release tablet |
WO2000018352A2 (en) * | 1998-09-28 | 2000-04-06 | Merck & Co., Inc. | A method for treating inflammatory diseases by administering a thrombin inhibitor |
BR0007453A (pt) * | 1999-01-13 | 2001-10-30 | Astrazeneca Ab | Composto, formulação farmacêutica, uso de umcomposto, método de tratamento de uma condiçãoonde a inibição da trombina é requerida e,processo de preparação de um composto |
WO2002014270A1 (en) * | 2000-08-16 | 2002-02-21 | Astrazeneca Ab | New amidino derivatives and their use as thrombin inhibitors |
AR035216A1 (es) * | 2000-12-01 | 2004-05-05 | Astrazeneca Ab | Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios |
SE0201659D0 (sv) * | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | Modified release pharmaceutical formulation |
-
2002
- 2002-05-31 SE SE0201658A patent/SE0201658D0/xx unknown
-
2003
- 2003-05-27 IL IL16506903A patent/IL165069A0/xx unknown
- 2003-05-27 NZ NZ536739A patent/NZ536739A/en not_active IP Right Cessation
- 2003-05-27 AU AU2003241239A patent/AU2003241239B2/en not_active Ceased
- 2003-05-27 JP JP2004508781A patent/JP4537197B2/ja not_active Expired - Fee Related
- 2003-05-27 WO PCT/SE2003/000857 patent/WO2003101423A1/en active Application Filing
- 2003-05-27 BR BR0311363-9A patent/BR0311363A/pt not_active IP Right Cessation
- 2003-05-27 UA UA20041109446A patent/UA82191C2/uk unknown
- 2003-05-27 US US10/516,423 patent/US20060014734A1/en not_active Abandoned
- 2003-05-27 PL PL03373908A patent/PL373908A1/xx unknown
- 2003-05-27 CN CNA038124904A patent/CN1655760A/zh active Pending
- 2003-05-27 CA CA002485533A patent/CA2485533A1/en not_active Abandoned
- 2003-05-27 SG SG2006083430A patent/SG172473A1/en unknown
- 2003-05-27 MX MXPA04011943A patent/MXPA04011943A/es active IP Right Grant
- 2003-05-27 KR KR10-2004-7019465A patent/KR20050010016A/ko not_active Application Discontinuation
- 2003-05-27 RU RU2004133387/15A patent/RU2351314C2/ru not_active IP Right Cessation
- 2003-05-27 EP EP03730964A patent/EP1513496A1/en not_active Withdrawn
- 2003-05-30 AR ARP030101933A patent/AR039935A1/es not_active Application Discontinuation
- 2003-05-30 TW TW092114804A patent/TWI311555B/zh active
- 2003-05-30 TW TW096117054A patent/TW200735864A/zh unknown
- 2003-11-30 SA SA03240403A patent/SA03240403B1/ar unknown
-
2004
- 2004-11-04 NO NO20044810A patent/NO20044810L/no not_active Application Discontinuation
- 2004-11-17 ZA ZA200409237A patent/ZA200409237B/en unknown
- 2004-12-03 IS IS7582A patent/IS7582A/is unknown
-
2008
- 2008-10-23 RU RU2008141850/15A patent/RU2008141850A/ru unknown
- 2008-11-07 CL CL2008003324A patent/CL2008003324A1/es unknown
-
2010
- 2010-03-03 AU AU2010200821A patent/AU2010200821A1/en not_active Abandoned
- 2010-04-26 JP JP2010100905A patent/JP2010209090A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2003241239A1 (en) | 2003-12-19 |
IL165069A0 (en) | 2005-12-18 |
TWI311555B (en) | 2009-07-01 |
CA2485533A1 (en) | 2003-12-11 |
TW200735864A (en) | 2007-10-01 |
NO20044810L (no) | 2005-02-24 |
NZ536739A (en) | 2006-10-27 |
RU2004133387A (ru) | 2005-07-10 |
AU2003241239B2 (en) | 2010-03-18 |
BR0311363A (pt) | 2005-03-01 |
CN1655760A (zh) | 2005-08-17 |
PL373908A1 (en) | 2005-09-19 |
KR20050010016A (ko) | 2005-01-26 |
CL2008003324A1 (es) | 2009-03-06 |
SE0201658D0 (sv) | 2002-05-31 |
JP4537197B2 (ja) | 2010-09-01 |
TW200400940A (en) | 2004-01-16 |
SG172473A1 (en) | 2011-07-28 |
UA82191C2 (uk) | 2008-03-25 |
US20060014734A1 (en) | 2006-01-19 |
AU2010200821A1 (en) | 2010-03-25 |
IS7582A (is) | 2004-12-03 |
SA03240403B1 (ar) | 2008-12-23 |
JP2005536471A (ja) | 2005-12-02 |
WO2003101423A1 (en) | 2003-12-11 |
RU2351314C2 (ru) | 2009-04-10 |
AR039935A1 (es) | 2005-03-09 |
JP2010209090A (ja) | 2010-09-24 |
EP1513496A1 (en) | 2005-03-16 |
MXPA04011943A (es) | 2005-03-31 |
RU2008141850A (ru) | 2010-04-27 |
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